17 research outputs found
Acquired complement C1 esterase inhibitor deficiency in a patient with a rare SERPING1 variant with unknown significance
Gene transcription profiles of paired mucoid and non-mucoid P. aeruginosa isolates from sinuses and lungs of patients with cystic fibrosis
The potential role of biological treatment of chronic rhinosinusitis with nasal polyps:A nationwide cohort study*
Sinus bacteriology in patients with cystic fibrosis or primary ciliary dyskinesia:A systematic review
CT of the paranasal sinuses is not a valid indicator for sinus surgery in CF patients
AbstractBackgroundNo guidelines comprise when or to what extent sinus surgery should be done in patients with cystic fibrosis (CF) or how a CT scan of the paranasal sinuses should influence the decision. Symptoms of rhinosinusitis and/or eradication of pathogenic bacteria from the sinuses are reasons for sinus surgery.MethodsIn this observational cross sectional study, 55 CF cases had their preoperative CT scans scored according to the Lund Mackay- and the Nair-system. Correlations between the CT scans, symptoms, surgical findings and cultures obtained during sinus surgery were made.ResultsThere was no significant correlation between the CT score and detection of pus, pathogenic bacteria or symptoms. Pus and pathogenic bacteria were found in several cases without sinus opacification on the CT scan. Non pathogenic and sterile cultures were also found in sinuses with opacification.ConclusionsA CT scan is not a valid criterion for sinus surgery in CF patients