Improving interoperability among learning objects using FIPA agent communication framework

The reusability of learning material is based on three main features: modularity, discoverability and interoperability. Several researchers on Intelligent Learning Environments have proposed the use of architectures based on agent societies. Learning systems based on Multi-Agent architectures support the development of more interactive and adaptable systems and the Learning Objects approach gives reusability. We proposed an approach where learning objects are built based on agent architectures. This paper discusses how the Intelligent Learning Objects approach can be used to improve the interoperability between learning objects and pedagogical agents.Applications in Artificial Intelligence - AgentsRed de Universidades con Carreras en Informática (RedUNCI

Intelligent learning objects: an agent aproach to create interoperable learning objects

Reusing learning material is very important to design learning environments for real-life learning. The reusability of learning objects results from the product of three main features: modularity, discoverability and interoperability. We proposed learning objects built based on agent architectures, called Intelligent Learning Objects (ILO). This paper discusses how the ILO approach can be used to improve the interoperability among learning objects, learning menagement systems (LMS) and pedagogical agents.Education for the 21 st century - impact of ICT and Digital Resources ConferenceRed de Universidades con Carreras en Informática (RedUNCI

Institutionalising smart city research and innovation: from fuzzy definitions to real-life experiments

By exploring and defining characteristics of a smart city research and innovation centre, we contribute to the discussion on smart city development capacity. To do so, using a qualitative method, we review definitions of the concept and map international groups and institutes affiliated with this domain. Our main result is an overview of global research centres dealing with smart cities. One of the key implications of this paper is that instead of a strict definition, the important aspect appears in the framing provided by the complex real-life challenges that require and enable cross-disciplinary research, even though the concept keeps evolving

Neoadjuvant chemotherapy and trastuzumab versus neoadjuvant chemotherapy followed by post-operative trastuzumab for patients with HER2-positive breast cancer

Neoadjuvant chemotherapy plus trastuzumab (NCT) increases the rate of pathological complete response (pCR) and event-free survival (EFS) compared to neoadjuvant chemotherapy (NC) alone in women with HER2 positive breast cancer (BC). pCR in this setting is associated with improved EFS. Whether NCT preferentially improves EFS in comparison to NC followed by adjuvant trastuzumab initiated postoperatively (NCAT) has not been addressed. Using clinical data from women with HER2 positive BC treated at 7 European institutions between 2007 and 2010 we sought to investigate the impact on breast cancer outcomes of concomitant (NCT) versus sequential (NCAT) treatment in HER2 positive early BC. The unadjusted hazard ratio (HR) for event free survival with NCT compared with NCAT was 0.63 (95% CI 0.37–1.08; p = 0.091). Multivariable analysis revealed that treatment group, tumour size and ER status were significantly associated with EFS from diagnosis. In the whole group NCT was associated with a reduced risk of an event relative to NCAT, an effect that was confined to ER negative (HR: 0.25; 95% CI, 0.10–0.62; p = 0.003) as opposed to ER positive tumours (HR: 1.07; 95% CI, 0.46–2.52; p = 0.869). HER2 positive/ER negative BC treated with NC gain greatest survival benefit when trastuzumab is administered in both the neoadjuvant and adjuvant period rather than in the adjuvant period alone. These data support the early introduction of targeted combination therapy in HER2 positive/ER negative BC

Projeto Marca - avaliação da implantação do projeto na ETB, safra 2004/05.

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Avaliação dos impactos ambientais e econômicos da cultivar de arroz irrigado BRS Querência.

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