COMPARATIVE ASSESSMENT OF REMOTE RESULTS OF NON-PHARMACOLOGICAL METHODS OF COMPLEX TREATMENT OF OBLITERATING ATHEROSCLEROSIS OF THE LOWER EXTREMITIES IN PATIENTS OF ELDERLY AND SENILE AGE

Aim - to estimate the remote results of treatment of obliterating atherosclerosis of arteries of the lower extremities of the II stage in patients of advanced and senile age after the combined use of ozone therapy and gravitational therapy. Materials and methods. A prospective randomized study in three parallel groups comprised 139 patients. The first group (n = 57) received standard medical therapy in combination with ozone therapy; the group was divided into two subgroups: the patients of subgroup 1a (n = 28) received intravenous ozonated physiological solution, in subgroup 1b (n = 29) - major ozonated autohemotherapy (MOA). Patients of the second group (n = 62) underwent comprehensive treatment, including gravitational therapy (GT) in addition to medical ozone. In this group we also identified two subgroups: subgroup 2a (n = 31), in which the patients received standard medical therapy in combination with ozonated physiological solution and gravitational therapy, and subgroup 2b (n = 31), in which the treatment was amplified by MOA and GT. The third group was the control group (n = 20) that included patients who received only standard medical therapy. Dynamics of changes of disease stages and the number of surgeries in the remote period was estimated (up to 7 years). Results. After 6 months of follow-up observation, the distribution of the disease stages among the patients did not differ significantly (p> 0.05) from the initial amount. Analysis of survival and probable risks after 7 years of follow-up by Cox regression method in relation to the applied method of treatment revealed maximum efficiency of combined treatment in subgroup 2a. Conclusion. As a result of complex conservative treatment, including ozonotherapy and gravitational therapy, the probability of surgical interventions as well as disease stage advancing were effectively reduced