11,658 research outputs found
Single Jejunum Metastasis from Breast Cancer Arising Twelve Years after the Initial Treatment
Metastatic involvement of gastrointestinal tract from breast cancer is a rare event. We report the case of a 61-year-old woman presenting with bowel obstruction, related to metastasis of a primary breast cancer she had 12 years earlier (a triple-negative invasive ductal carcinoma treated with surgery and chemotherapy). Bowel obstruction was caused by a 20-centimeter tumor in the jejunum, involving also the transverse colon. The patient underwent en bloc resection of tumor with jejunum and transverse bowel segment and received adjuvant chemotherapy with carboplatin and paclitaxel. Twenty months later, she was alive without disease recurrence.info:eu-repo/semantics/publishedVersio
Enhanced propagation of motile bacteria on surfaces due to forward scattering
How motile bacteria move near a surface is a problem of fundamental
biophysical interest and is key to the emergence of several phenomena of
biological, ecological and medical relevance, including biofilm formation.
Solid boundaries can strongly influence a cell's propulsion mechanism, thus
leading many flagellated bacteria to describe long circular trajectories stably
entrapped by the surface. Experimental studies on near-surface bacterial
motility have, however, neglected the fact that real environments have typical
microstructures varying on the scale of the cells' motion. Here, we show that
micro-obstacles influence the propagation of peritrichously flagellated
bacteria on a flat surface in a non-monotonic way. Instead of hindering it, an
optimal, relatively low obstacle density can significantly enhance cells'
propagation on surfaces due to individual forward-scattering events. This
finding provides insight on the emerging dynamics of chiral active matter in
complex environments and inspires possible routes to control microbial ecology
in natural habitats
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