Chapter 5 : Deciduous Tooth Resorption after Overfilling of Root Canal Filler: Function and Nature of Multinucleated Giant Cells

There are numerous reports on physiological root resorption claiming that the root resorption process of primary teeth is regulated in a manner similar to bone remodeling [28]. However, complex histological changes occur under several pathological conditions. Abnormal tooth resorption could be found in primary teeth due to certain causes until the completion of the permanent dentition. In Japan and eastern Asia, calcium hydroxide paste with silicon oil added iodoform is widely used for endodontic treatment of deciduous teeth. This material is sometimes excessively filled within root canals, and pathological reactions have been already discussed in previous sections. In this part, the influences on deciduous tooth endodontic therapy will be described in detail. The most characteristic feature is abnormal tooth resorption via osteoclast-like multinucleated giant cells (MGCs) and foreign body giant cells (FBGCs). In the later part of this section, the characteristics of foreign body type giant cells will be discussed through in vivo experiments.Editor, Toshiyuki KawakamiLanguage Editor, David M Carlsonviii, 232 p. ill. (some col.

術後性上顎嚢壁にみられた石灰化物の観察

Light and scanning electron microscopic observations and electron probe microanalysis were carried out on granular calcified bodies that appeared in the wall of a postoperative maxillary cyst in a 59-year-old man. The granular bodies, stained slightly with hematoxylin, were scattered in the cyst wall. They reacted positively to von Kossa\u27s stain indicating calcification. Based on scanning electron microscopic observation, secondary electron images revealed them to be compact bodies, and they appeared as light spots in composition images. Electron probe microanalysis revealed that the bodies were ccomposed mainly of calcium and phosphorus. Some of the large bodies had a membranous calcification core, which was observed especially in von Kossa\u27s stained specimens. Therefore, we believe that these calcification core must be generated cell debris, cell membrane, nuclear membrane or subcellular organelles