76 research outputs found
An open-label, phase IV randomised controlled trial of two schedules of a four-component meningococcal B vaccine in UK preterm infants
Objective: To compare immunological responses of preterm infants to a four-component meningococcal B vaccine (4CMenB; Bexsero) following a 2+1 vs a 3+1 schedule, and to describe reactogenicity of routine vaccines. Design: An open-label, phase IV randomised study conducted across six UK sites. Setting: Neonatal units, postnatal wards, community recruitment following discharge. Participants: 129 preterm infants born at a gestation of 38.0°C than those in the 2+1 group who did not (group 2+1: 2% (n=1); 3+1: 14% (n=9); p=0.02). Conclusions: Both schedules were immunogenic in preterm infants, although a lower response against strain NZ98/254 was seen in the 2+1 schedule; ongoing disease surveillance is important in understanding the clinical significance of this difference. Trial registration number: NCT03125616
An open-label, phase IV randomised controlled trial of two schedules of a four-component meningococcal B vaccine in UK preterm infants
Objective: To compare immunological responses of preterm infants to a four-component meningococcal B vaccine (4CMenB; Bexsero) following a 2+1 vs a 3+1 schedule, and to describe reactogenicity of routine vaccines. Design: An open-label, phase IV randomised study conducted across six UK sites. Setting: Neonatal units, postnatal wards, community recruitment following discharge. Participants: 129 preterm infants born at a gestation of 38.0°C than those in the 2+1 group who did not (group 2+1: 2% (n=1); 3+1: 14% (n=9); p=0.02). Conclusions: Both schedules were immunogenic in preterm infants, although a lower response against strain NZ98/254 was seen in the 2+1 schedule; ongoing disease surveillance is important in understanding the clinical significance of this difference. Trial registration number NCT03125616
Pope Martin I and Maximos the Confessor in Their Struggle for Orthodoxy Against the Empire
(VLID)276569
Biblical Exegesis and the Formation of Christian Culture. By Frances M. Young. Cambridge: Cambridge University Press, 1997. Pp. xiv + 325 £37.50.
St Augustine, Confessions. Translated with an introduction and notes by Henry Chadwick. Oxford University Press, 1991. Pp. xxix + 311. £17.50.
The first thousand years. A global history of Christianity. By Robert Louis Wilken. Pp. x+388 incl. 6 maps+16 colour plates. New Haven–London: Yale University Press, 2012. £25. 978 0 300 11884 1
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