Fabrication Of An Electronic Nose And Its Application For The Verification Of Eurycoma Longifolia Extracts [TP159.C46 I82 2007 f rb].

Hidung elekronik yang berasaskan penderia penimbang mikro hablur kuarza menggunakan etil selulosa, lipid (dioktil fosfat (DOP), trioktil metil ammonium klorida (TOMA), olil amina (OAm)) dan bahan fasa pegun kromatografi gas (Apiezon L (APZL),polipropilin glikol 1200 (PPG 1200), polietilina glikol 1000 (PEG 1000), polietilina glikol 4000 (PEG 4000), poli(bissanopropil-siloksana) (OV-275) dan dietilina glikolsuksinat (DEGS) sebagai membran penderia untuk menganalisis ekstrak daripada Eurycoma longifolia (Tongkat Ali) telah dibina. An electronic nose based on a quartz crystal microbalance array sensor using ethylcellulose (EC), lipids ((dioctyl phosphate (DOP), trioctyl methyl ammonium chloride (TOMA), oleyl amine (OAm)) and gas chromatography (GC) stationary phase materials ((Apiezon-L (APZ-L), polypropylene glycol 1200 (PPG 1200), polyethylene glycol 1000 (PEG 1000), polyethylene glycol 4000 (PEG 4000), poly(biscyanopropyl-siloxane) (OV-275) and diethylene glycol succinate (DEGS)) as sensing membrane for the analysis ofextracts of Eurycoma longifolia (Tongkat Ali) was develope

Fabrication Of An Electronic Nose And Its Application For The Verification Of Eurycoma Longifolia Extracts

An electronic nose based on a quartz crystal microbalance array sensor using ethyl cellulose (EC), lipids «dioetyl phosphate (DOP). triaetyl methyl ammonium chloride (TOMA), oleyl amine (OAm» and gas chromatography (GC) stationary phase materials «Apiezo

VIRTUAL SEARCHING OF DUMMY TEMPLATE FOR SINENSETIN BASED ON 2D MOLECULAR SIMILARITY USING CHEMDB TOOL

Sinensetin-like molecules have been searched virtually to find a dummy template for Molecular Imprinted Polymer (MIP) synthesis. The aim of this study is to find a novel adsorbent for Solid Phase Extraction (SPE) of sinensetin based on tailored method using dummy template. Virtual searching was done using ChemDB online chemical database containing 5 million commercially available chemicals. Sinensetin as target was converted into SMILES code then it was run with threshold of molecular similarity score of 0.5. There were 90 chemical structures given as the output mainly flavone analogue, three flavonols and several non-flavonoid compounds. The suggested results are three dummy templates that derived from luteolin (flavon) or quercetin (flavonol) with slight alteration by methoxylation process

Development of Multichannel Artificial Lipid-Polymer Membrane Sensor for Phytomedicine Application

Quality control of herbal medicines remain a challenging issue towardsintegrating phytomedicine into the primary health care system. As medicinal plants is acomplicated system of mixtures, a rapid and cost-effective evaluation method tocharacterize the chemical fingerprint of the plant without performing laborious samplepreparation procedure is reported. A novel research methodology based on an in-housefabricated multichannel sensor incorporating an array of artificial lipid-polymer membraneas a fingerprinting device for quality evaluation of a highly sought after herbal medicine inthe Asean Region namely Eurycoma longifolia (Tongkat Ali). The sensor array is based onthe principle of the bioelectronic tongue that mimics the human gustatory system throughthe incorporation of artificial lipid material as sensing element. The eight non-specificsensors have partially overlapping selectivity and cross-sensitivity towards the targetedanalyte. Hence, electrical potential response represented by radar plot is used to characterizeextracts from different parts of plant, age, batch-to-batch variation and mode of extraction ofE. longifolia through the obtained potentiometric fingerprint profile. Classification modelwas also developed classifying various E. longifolia extracts with the aid of chemometricpattern recognition tools namely hierarchical cluster analysis (HCA) and principalcomponent analysis (PCA). The sensor seems to be a promising analytical device for qualitycontrol based on potentiometric fingerprint analysis of phytomedicine