56 research outputs found
Mineralocorticoid receptor antagonists for heart failure: systematic review and meta-analysis
Nonequilibrium thermodynamics and energy efficiency in weight loss diets
Carbohydrate restriction as a strategy for control of obesity is based on two effects: a behavioral effect, spontaneous reduction in caloric intake and a metabolic effect, an apparent reduction in energy efficiency, greater weight loss per calorie consumed. Variable energy efficiency is established in many contexts (hormonal imbalance, weight regain and knock-out experiments in animal models), but in the area of the effect of macronutrient composition on weight loss, controversy remains. Resistance to the idea comes from a perception that variable weight loss on isocaloric diets would somehow violate the laws of thermodynamics, that is, only caloric intake is important ("a calorie is a calorie"). Previous explanations of how the phenomenon occurs, based on equilibrium thermodynamics, emphasized the inefficiencies introduced by substrate cycling and requirements for increased gluconeogenesis. Living systems, however, are maintained far from equilibrium, and metabolism is controlled by the regulation of the rates of enzymatic reactions. The principles of nonequilibrium thermodynamics which emphasize kinetic fluxes as well as thermodynamic forces should therefore also be considered
Association of household secondhand smoke exposure and mortality risk in patients with heart failure
Cultural repertoires and modern menaces : the media’s racialised coverage of child sexual exploitation
This chapter will discuss the mass media’s coverage of child sexual exploitation (CSE) cases in Rochdale (Greater Manchester) and Rotherham (South Yorkshire). These cases gained prominent media attention in the period between 2010 and 2015. The cases involved male abusers of black and minority ethnic (BME) background, in particular of Pakistani heritage and of Muslim faith, who had been abusing young female victims. Although some of the victims were also of the same ethnic background as the abusers, media attention selectively focused on those victims who were of white ethnic background. The chapter argues that the cases were narrated entirely through a cultural repertoire, and drew on older racialized panics about the brown menace and white victims. The problem here is that the crime of CSE in these locales (and others like it) became racialized – presented as a form of culturally-specific deviance, rather than one about gender and power, this process of ‘browning’ not only created a newer category of the black folk devil, and thus ignored white perpetrators, but also served to marginalise all victims of such abuse. A comment on the media’s racialized (re)presentation of these CSE cases takes into account their relative power in modern society, as well as their status, along with other elites, as joint-producers of information about race and racism (van Dijk, 2000: 36)
The major genetic risk factor for severe COVID-19 does not show any association among South Asian populations
2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society
A Critical Review of Hemodynamically Guided Therapy for Cardiogenic Shock: Old Habits Die Hard
- …