559 research outputs found
Hopf-algebra description of noncommutative-spacetime symmetries
In the study of certain noncommutative versions of Minkowski spacetime there
is still a large ambiguity concerning the characterization of their symmetries.
Adopting as our case study the kappaMinkowski noncommutative space-time, on
which a large literature is already available, we propose a line of analysis of
noncommutative-spacetime symmetries that relies on the introduction of a Weyl
map (connecting a given function in the noncommutative Minkowski with a
corresponding function in commutative Minkowski) and of a compatible notion of
integration in the noncommutative spacetime. We confirm (and we establish more
robustly) previous suggestions that the commutative-spacetime notion of
Lie-algebra symmetries must be replaced, in the noncommutative-spacetime
context, by the one of Hopf-algebra symmetries. We prove that in kappaMinkowski
it is possible to construct an action which is invariant under a Poincare-like
Hopf algebra of symmetries with 10 generators, in which the noncommutativity
length scale has the role of relativistic invariant. The approach here adopted
does leave one residual ambiguity, which pertains to the description of the
translation generators, but our results, independently of this ambiguity, are
sufficient to clarify that some recent studies (gr-qc/0212128 and
hep-th/0301061), which argued for an operational indistiguishability between
theories with and without a length-scale relativistic invariant, implicitly
assumed that the underlying spacetime would be classical.Comment: 20 pages, no figures, LaTex. This version has exactly the same
technical content as version 1, but the observation reported in Section VII
is discussed more pedagogicall
The maximum likelihood degree of Fermat hypersurfaces
We study the critical points of the likelihood function over the Fermat
hypersurface. This problem is related to one of the main problems in
statistical optimization: maximum likelihood estimation. The number of critical
points over a projective variety is a topological invariant of the variety and
is called maximum likelihood degree. We provide closed formulas for the maximum
likelihood degree of any Fermat curve in the projective plane and of Fermat
hypersurfaces of degree 2 in any projective space. Algorithmic methods to
compute the ML degree of a generic Fermat hypersurface are developed throughout
the paper. Such algorithms heavily exploit the symmetries of the varieties we
are considering. A computational comparison of the different methods and a list
of the maximum likelihood degrees of several Fermat hypersurfaces are available
in the last section.Comment: Final version. Accepted for publication on Journal of Algebraic
Statistic
Enabling RAN Slicing Through Carrier Aggregation in mmWave Cellular Networks
The ever increasing number of connected devices and of new and heterogeneous
mobile use cases implies that 5G cellular systems will face demanding technical
challenges. For example, Ultra-Reliable Low-Latency Communication (URLLC) and
enhanced Mobile Broadband (eMBB) scenarios present orthogonal Quality of
Service (QoS) requirements that 5G aims to satisfy with a unified Radio Access
Network (RAN) design. Network slicing and mmWave communications have been
identified as possible enablers for 5G. They provide, respectively, the
necessary scalability and flexibility to adapt the network to each specific use
case environment, and low latency and multi-gigabit-per-second wireless links,
which tap into a vast, currently unused portion of the spectrum. The
optimization and integration of these technologies is still an open research
challenge, which requires innovations at different layers of the protocol
stack. This paper proposes to combine them in a RAN slicing framework for
mmWaves, based on carrier aggregation. Notably, we introduce MilliSlice, a
cross-carrier scheduling policy that exploits the diversity of the carriers and
maximizes their utilization, thus simultaneously guaranteeing high throughput
for the eMBB slices and low latency and high reliability for the URLLC flows.Comment: 8 pages, 8 figures. Proc. of the 18th Mediterranean Communication and
Computer Networking Conference (MedComNet 2020), Arona, Italy, 202
Comment on âearly efficacy of intra-articular HYADDÂź 4 (HymovisÂź) injections for symptomatic knee osteoarthritisâ
We read with great interest the study by Priano titledâEarly
efficacy of intra-articular HYADDÂź 4 (HymovisÂź) injections
for symptomatic knee osteoarthritis.â
1
The author would like
to explore the efficacy of intra-articular HYADD 4 (Hymovis)
injections for symptomatic knee osteoarthritis. Results from
this study are very interesting and promising from a clinical
aspect; however, we believe that studying patientâsclinical
status with visual analog scale and Western Ontario and
McMaster Universities Arthritis Index scale should be supported by biomechanical information. From this point of
view, to have more data that could influence the clinical
practice, it is important to note the possible action that intraarticular injections of different kinds of hyaluronic acid could
have on walking biomechanics using an objective measurement tool as gait analysis. In our opinion, the work by Priano1
is promising because it investigates the efficacy of a new
formulation of hyaluronic acid. Nowadays, many hyaluronic
acid formulations are approved for clinical use in Europe and
the United States. Furthermore, hyaluronic acid injectionsâ
efficacy has been demonstrated also in hip osteoarthritis.
2
However, even if these formulations differ in their chemicalâ
physical properties, joint space half-life, rheological properties, and clinical efficacy, there are few studies that investigate hyaluronic acidâs possible action from a biomechanical
point of view.
3,4
From this point of view, we believe that
osteoarthritis management and rehabilitation should be
prescribed after an objective analysis of functional walking
alterations using gait analysis instrumentations. The use
of gait analysis should be desirable during diagnosis and
follow-up. In fact, it is capable to identify different walking
patterns in patient with osteoarthritis of the lower limbs,
whereas the radiology can evaluate the status of the jointâs
structures
A Multiscale Thermo-Fluid Computational Model for a Two-Phase Cooling System
In this paper, we describe a mathematical model and a numerical simulation
method for the condenser component of a novel two-phase thermosyphon cooling
system for power electronics applications. The condenser consists of a set of
roll-bonded vertically mounted fins among which air flows by either natural or
forced convection. In order to deepen the understanding of the mechanisms that
determine the performance of the condenser and to facilitate the further
optimization of its industrial design, a multiscale approach is developed to
reduce as much as possible the complexity of the simulation code while
maintaining reasonable predictive accuracy. To this end, heat diffusion in the
fins and its convective transport in air are modeled as 2D processes while the
flow of the two-phase coolant within the fins is modeled as a 1D network of
pipes. For the numerical solution of the resulting equations, a Dual
Mixed-Finite Volume scheme with Exponential Fitting stabilization is used for
2D heat diffusion and convection while a Primal Mixed Finite Element
discretization method with upwind stabilization is used for the 1D coolant
flow. The mathematical model and the numerical method are validated through
extensive simulations of realistic device structures which prove to be in
excellent agreement with available experimental data
Simulating the Impact on the Local Economy of Alternative Management Scenarios for Natural Areas
This working paper estimates the impact on the local economy of the High Garda Natural Park of alternative management scenarios for the West Garda Regional Forest. The local economy is specialized in tourist services and strongly linked to the tourist presence and their level of expenditure. We wish to investigate the effects of the participative management strategy, which takes into account users preferences and the non-participative strategy, using the SAM multiplier analysis. The local SAM has been constructed considering three sectors: agriculture, tourism and a third aggregate sector including all the other activities. The resident population has been divided into two categories: residents employed in the tourist sector and the remaining resident population. The SAM analysis shows that the accounting representation of the local economy is meaningful and that the participative program, if chosen by the central regional management, would be the most desirable program also at the local level.Tourism, SAM, Multiplier analysis
Linking ROS Levels to Autophagy: The Key Role of AMPK
Oxygen reactive species (ROS) are a group of molecules generated from the incomplete reduction of oxygen. Due to their high reactivity, ROS can interact with and influence the function of multiple targets, which include DNA, lipids, and proteins. Among the proteins affected by ROS, AMP-activated protein kinase (AMPK) is considered a major sensor of the intracellular energetic status and a crucial hub involved in the regulation of key cellular processes, like autophagy and lysosomal function. Thanks to these features, AMPK has been recently demonstrated to be able to perceive signals related to the variation of mitochondrial dynamics and to transduce them to the lysosomes, influencing the autophagic flux. Since ROS production is largely dependent on mitochondrial activity, through the modulation of AMPK these molecules may represent important signaling agents which participate in the crosstalk between mitochondria and lysosomes, allowing the coordination of these organelles' functions. In this review, we will describe the mechanisms through which ROS activate AMPK and the signaling pathways that allow this protein to affect the autophagic process. The picture that emerges from the literature is that AMPK regulation is highly tissue-specific and that different pools of AMPK can be localized at specific intracellular compartments, thus differentially responding to altered ROS levels. For this reason, future studies will be highly advisable to discriminate the specific contribution of the activation of different AMPK subpopulations to the autophagic pathway
Prvi zapis o novoj obojanosti kirnje zlatice, Epinephelus costae (Steindachner, 1878) (Actinopterygii: Serranidae) i prvi zapis o leucizmu ugora, Conger conger (Linnaeus, 1758) (Actinopterygii: Congridae): graÄanski doprinos znanosti
In many fish, color patterns are striking features and can play an important role in both natural and sexual selection. Furthermore, details of color patterns are in some cases valid tools for species identification. However, fish can also show some genetic abnormalities, such as albinism and leucism. In this research, we report for the first time a new color pattern for Epinephelus costae (Steindachner, 1878), for which it is known an ontogenetic shift in color pattern, and the first case of leucism in Conger conger (Linnaeus, 1758).Kod mnogih riba obojanost ima upeÄatljiva obiljeĆŸja i moĆŸe igrati vaĆŸnu ulogu kako u prirodnom tako i u spolnom odabiru. Detalji o uzorcima boja u nekim su sluÄajevima valjani alat za identifikaciju vrsta. MeÄutim, riba moĆŸe pokazati i neke genetske abnormalnosti, poput albinizma i leucizma. U ovom istraĆŸivanju prvi put izvjeĆĄÄujemo o novoj obojanosti Epinephelus costae (Steindachner, 1878.) i o prvom sluÄaju leucizma kod ugora, Conger conger (Linnaeus, 1758)
Boiling on a tube bundle:heat transfer, pressure drop and flow patterns
The complexity of the two-phase flow in a tube bundle presents important problems in the design and understanding of the physical phenomena taking place. The working conditions of an evaporator depend largely on the dynamics of the two-phase flow that in turn influence the heat exchange and the pressure drop of the system. A characterization of the flow dynamics, and possibly the identification of the flow pattern in the tube bundle, in thus expected to lead to a better understanding of the phenomena and to reveal on the mechanisms governing the tube bundle. Therefore, the present study aims at providing further insights into two-phase bundle flow through a new visualization system able to provide for the first time a view of the flow in the core of a tube bundle. In addition, the measurement of the light attenuation of a laser beam through the two-phase flow and measurement of the high frequency pressure fluctuations with a piezo-electric pressure transducer are used to characterize the flow. The design and the validation of this new instrumentation also provided a method for the detection of dry-out in tube bundles. This was achieved by a laser attenuation technique, flow visualization, and estimation of the power spectrum of the pressure fluctuation. The current investigation includes results for two different refrigerants, R134a and R236fa, three saturations temperatures Tsat = 5, 10 and 15 °C, mass velocities ranging from 4 to 40 kg/sm2 in adiabatic and diabatic conditions (several heat fluxes). Measurement of the local heat transfer coefficient and two-phase frictional pressure drop were obtained and utilized to improve the current prediction methods. The heat transfer and pressure drop data were supported by extensive characterization of the two-phase flow, which was to improve the understanding of the two-phase flow occurring in tube bundles
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