8 research outputs found
Culture in embryonic kidney serum and xeno-free media as renal cell carcinoma and renal cell carcinoma cancer stem cells research model
- Author
- A Buckler
- A Franovic
- A Pause
- AF Tracz
- AM Czarnecka
- Anna M. Czarnecka
- Camillo Porta
- Cezary Szczylik
- Damian Matak
- DG Maggs
- E Ulukaya
- F Stehle
- FL Graham
- G Bhave
- G Gstraunthaler
- G Shah
- H Kamei
- H Wang
- HD Patel
- J Marazzi
- J O’Brien
- J Valk van der
- JFB Paschoal
- K Smith
- KD Sarma
- Krzysztof M. Krawczyk
- L Cervera
- Lukasz Szymanski
- M Taub
- M Zeisberg
- MB Hansen
- MJ Evans
- MJ Farrell
- P Goegan
- PA Kenny
- PJ Curran
- PN Teng
- R Fike
- RJ Geraghty
- RJ Gonzalez
- S Prior
- SN Rampersad
- TL Riss
- W Solarek
- X Zheng
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Identification of miRNA signatures for kidney renal clear cell carcinoma using the tensor-decomposition method
- Author
- A Liberzon
- A Rouhi
- AF Tracz
- AP Feinberg
- C Doehn
- D Hanahan
- E Sarnowska
- H Zhou
- JM Major
- K Ishibashi
- K Kaminska
- LC Macleod
- M Lee
- M Xie
- ME Ritchie
- N Piazzon
- N Unver
- PK Jaiswal
- PP Medina
- R Braczkowski
- SD Lokeshwar
- T Inamoto
- VE Torres
- W Solarek
- W Zhang
- XH Shi
- Y Luo
- Y Yu
- Y Zang
- Y-H Taguchi
- Y-H Taguchi
- Y-H Taguchi
- Y-H Taguchi
- Y-H Taguchi
- Y-H Taguchi
- Y-H Taguchi
- Y-H Taguchi
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Cancer-associated fibroblasts promote cisplatin resistance in bladder cancer cells by increasing IGF-1/ERβ/Bcl-2 signalling
- Author
- AF Tracz
- B Han
- C Thomas
- C Tuygun
- CJ Cookman
- DJ Gallagher
- DJ Hsieh
- E Sanchez-Lopez
- E Scosyrev
- E Surmacz
- EC Kauffman
- G Dranoff
- H Miyake
- H Miyamoto
- H Shi
- H von der Maase
- H Yan
- HB Grossman
- HZ Sun
- I Hsu
- I Hsu
- J Budczies
- J Li
- J Zhuang
- JH Hong
- L Bjornstrom
- LA Torre
- LC Li
- M Koti
- M Pollack
- MB Cook
- MB Meads
- MI Mitchell
- O Trédan
- P Rizza
- PR Manna
- R Kalluri
- SA Hussain
- SC Ruddy
- SS Müerköster
- SS Shen
- T Tsujino
- UE Martinez-Outschoorn
- W Huang
- Y Kwak
- ZH Shen
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Targeting the insulin-like growth factor-1 receptor in MTAP-deficient renal cell carcinoma
- Author
- A Oza
- AA Hakimi
- AF Tracz
- AP Stevens
- B Tang
- CH Chen
- CH Chen
- CY Su
- DM Epstein
- EL Powell
- FC Henrich
- G Kirovski
- GV Kryukov
- HA Coller
- HG Williams-Ashman
- HI Wettersten
- HW Liao
- I Basu
- I Basu
- JM Hsu
- JR Bertino
- K Marjon
- KA Mowen
- KJ Mavrakis
- KK Biggar
- KM LaPak
- L Zhou
- M Braekeleer De
- M Chen
- M Santoni
- MA Avila
- MJ Mulvihill
- P Barata
- PA Boriack-Sjodin
- PB Illei
- RL Siegel
- RRJ Collins
- S Chattopadhyay
- S Marce
- SA Christopher
- SC Joosten
- SK Denduluri
- SR Hustinx
- T Gambichler
- T Nobori
- TE Ciuleanu
- WJ Woollard
- WT Iams
- X Wan
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Outcomes of androgen replacement therapy in adult male hypogonadism: recommendations from the Italian society of endocrinology
- Author
- A Aversa
- A Aversa
- A Ferlin
- AF Radicioni
- AG Cotter
- AM Isidori
- AM Isidori
- AM Isidori
- AM Isidori
- AM Isidori
- AM Kenny
- AM Matsumoto
- C Rolf
- C Steidle
- CJ Malkin
- D Francomano
- D Francomano
- D Kapoor
- EA Jannini
- ER Bolona
- FC Wu
- G Caminiti
- G Cavallini
- G Corona
- G Corona
- G Corona
- G Corona
- G Corona
- G Hackett
- G Huang
- G Tirabassi
- HR Amanatkar
- I Huhtaniemi
- J Buvat
- J Svartberg
- JE Morley
- JK Amory
- JM Johnson
- JP Ioannidis
- JS Tenover
- L Xu
- LS Marks
- MJ Tracz
- MM Fernandez-Balsells
- NT Shahidi
- OM Calof
- PJ Drinka
- PJ Snyder
- PJ Snyder
- PY Liu
- RA Condorelli
- RM Francis
- RM Haddad
- RR Hajjar
- S Bhasin
- ST Page
- SY Kalinchenko
- TH Jones
- U Srinivas-Shankar
- V Rochira
- WS Tan
- Z Merza
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Crosstalk between VEGFR and other receptor tyrosine kinases for TKI therapy of metastatic renal cell carcinoma
- Author
- A Guo
- A Vazquez-Martin
- AC Rapraeger
- AF Tracz
- AJ Wekken van der
- B Escudier
- B Escudier
- B Shuch
- C Miao
- C Prior
- C Shen
- Cancer Genome Atlas Research Network
- CL Arteaga
- CR Maroun
- D Huang
- DD Hu-Lowe
- Dong Chen
- DW Wu
- E Ciamporcero
- E Juengel
- EM Wallace
- FM Yakes
- GD Stewart
- Guohua Zeng
- H Cho
- HJ Hammers
- HT Tran
- J Faria
- J Liefers-Visser
- J Schodel
- J Wang
- J Xu
- JE Maxson
- JJ Hsieh
- JJ Hsieh
- JJ Wallin
- JK Bruner
- K Azuma
- K Ishibashi
- K Matusan-Ilijas
- K Sharpe
- KG Liu
- KM Mahoney
- L Albiges
- L Gu
- L Gunaratnam
- L Qu
- L Zhang
- M Frodin
- M Ghidini
- M Gilabert
- M Kowanetz
- M Santoni
- M Schmidinger
- M Terme
- MA Cruz-Morcillo De la
- MC Boelens
- MH Voss
- MH Voss
- MJ Martin
- NM Tannir
- O Martinez-Saez
- P Traxler
- P Zhang
- RA Figlin
- RH Giles
- RJ Motzer
- RJ Roskoski
- RJ Roskoski
- S Lin
- SA Brown
- SJ Shin
- SJ Wells
- T Funakoshi
- T Mitsudomi
- T Pemovska
- T Powles
- Tao Zeng
- TE Behbahani
- TK Choueiri
- TK Choueiri
- TM Cardillo
- V Damiano
- V Mazza
- W Chen
- W Solarek
- Wenqi Wu
- X Sheng
- Xiaolu Duan
- Xiongfa Liang
- XM Lai
- Y Cao
- Y Shen
- Y Zhao
- Yongchang Lai
- Z Xu
- Zhijian Zhao
- ZT Al-Salama
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Oral microbiome and health
- Author
- Abeles SR Robles-Sikisaka R, Ly M, et al.
- Ahn J Chen CY, Hayes RB
- Anand PS Nandakumar K, Shenoy KT
- Antunes LCM Ferreira RB, Buckner MM, et al.
- Arcavi L Benowitz NL
- Armitage GC
- Arrais JP Rosa N, Melo J, et al.
- Atanasova KR Yilmaz O
- Ausec L Kraighera B, Mandic-Mulec I
- Avila M Ojcius DM, Yilmaz O
- Awano S Ansai T, Takata Y, et al.
- Bahrani-Mougeot FK Paster BJ, Coleman S, et al.
- Bankevich A Nurk S, Antipov D, et al.
- Barnes VM Ciancio SG, Shibly O, et al.
- Beck JD Offenbacher S
- Belda-Ferre P Alcaraz LD, Cabrera-Rubio R, et al.
- Bik EM Long CD, Armitage GC, et al.
- Blaser MJ Atherton JC
- Borgnakke WS Ostalo PV, Taylor GW, et al.
- Boschker HTS Nold SC, Wellsbury P
- Brook I Gober AE
- Brook I Gober AE
- Burne RA Marquis RE
- Castro HF Classen AT, Austin EE, et al.
- Charlson ES Chen J, Custers-Allen R, et al.
- Chitsaz H Yee-Greenbaum JL, Tesler G
- Ciric L Brouwer MS, Mullany P
- Connell SR Tracz DM, Nierhaus KH
- Contreras M Costello EK, Hidalgo G, et al.
- Corby PM Bretz WA, Hart TC
- Darveau RP
- Davey M Otoole GA
- Dean FB Hosono S, Fang L
- Dewhirst FE Chen T, Izard J
- Diaz PI Chalmers NI, Rickard AH, et al.
- Dominguez-Bello MG Costello EK, Contreras M, et al.
- Duran-Pinedo AE Chen T, Teles R, et al.
- Edlund A Santiago-Rodriguez TM, Boehm TK, et al.
- Edwards AM Grossman TJ, Rudney JD
- El Ahmer OR Essery SD, Saadi AT, et al.
- Fullmer SC Preshaw PM, Heasman PA
- Galiminas V Hall MW, Singh N, et al.
- Genco RJ Grossi SG, Ho A, et al.
- Gevers D Knight R, Petrosino JF, et al.
- Ghannoum MA Jurevic RJ, Mukherjee PK, et al.
- Giacaman RA Asrani AC, Gebhard KH, et al.
- Griffen AL Beall CJ, Campbell JH, et al.
- Grover HS Blaggana A, Jain Y, et al
- He XS Shi WY
- Herzberg MC Weinberg A, Wahl SM
- Hoceini A Khelil NK, Ben-Yelles I, et al.
- Holgerson PL Harnevik L, Hernell O, et al.
- Holgerson PL Vestman NR, Claesson R, et al.
- Horner-Devine MC Lage M, Hughes JB, et al.
- Human Microbiome Jumpstart Reference Strains Consortium
- Human Microbiome Project Consortium
- Huse SM Ye Y, Zhou Y, et al.
- Huson DH Auch AF, Qi J, et al.
- Ide M Papapanou PN
- Jakubovics NS Gill SR, Vickerman MM, et al.
- Jenkinson HF Lamont RJ
- Jorth P Trivedi U, Rumbaugh K, et al.
- Joshi HM Toleti RS
- Joshipura KJ Hung HC, Rimm EB, et al.
- Kamer AR Dasanayake AP, Craig RG, et al.
- Kampfer J Gohring TN, Attin T, et al.
- Kaur S White S, Bartold PM
- Kleinberg I
- Kolenbrander PE
- Kolenbrander PE Andersen RN, Blehert DS, et al.
- Kort R Caspers M, Graff A, et al.
- Kreft JU
- Kreth J Merritt J, Shi W, et al.
- Kreth J Merritt J, Shi W, et al.
- Kumar PS Griffen AL, Barton JA, et al.
- Kuramitsu HK He X, Lux R, et al.
- Lasken RS
- Lepp PW Brinig MM, Ouverney CC, et al.
- Li J Quinque D, Horz HP, et al.
- Li K Bihan M, Methé BA
- Li Y Ismail AI, Ge Y, et al.
- Liu B Faller LL, Klitgord N, et al.
- Loning T Ikenberg H, Becker J, et al.
- Lourenço TGB Heller D, Silva-Boghossian CM
- Madhi SA Adrian P, Kuwanda L, et al.
- Marik PE
- Maron PA Ranjard L, Mougel C, et al.
- Mashburn-Warren LM Whiteley M
- Matarazzo F Ribeiro AC, Feres M, et al.
- McNab R Ford SK, El-Sabaeny A, et al.
- Miller MB Bassler BL
- Moon JH Lee JH
- Munson MA Banerjee A, Watson TF, et al.
- Munson MA Pitt-Ford T, Chong B, et al.
- Nasidze I Li J, Quinque D, et al.
- Nyvad B Kilian M
- Peek RM Blaser MJ
- Peterson J Garges S, Giovanni M, et al.
- Pride DT Salzman J, Haynes M, et al.
- Pride DT Salzman J, Haynes M, et al.
- Pride DT Salzman J, Relman DA
- Pushalkar S Ji X, Li Y, et al.
- Qin J Li R, Raes J, et al.
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- Raghavendran K Mylotte JM, Scannapieco FA
- Raghunathan A Ferguson HR, Bornarth CJ, et al.
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- Regev-Yochay G Trzciński K, Thompson CM, et al.
- Reid NM Addison SL, Macdonald LJ, et al.
- Scannapieco FA
- Scannapieco FA
- Segata N Haake SK, Mannon P, et al.
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- Socransky SS Haffajee AD, Cugini MA, et al.
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- Takahashi N Nyvad B
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- Vincent JL
- Walter J Ley R
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- Zaura E Keijser BJ, Huse SM, et al.
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- Publication venue
- 'American Institute of Mathematical Sciences (AIMS)'
- Publication date
- 01/01/2018
- Field of study
Ezetimibe added to statin therapy after acute coronary syndromes
- Author
- Aagnes I
- Aambakk MB
- Aase O
- Aaser E
- Abdel-Latief A
- Abell T
- Aboufakher R
- Abramson B
- Abrantes J
- Achilli A
- Adams A
- Adams K
- Adamus J
- Addington J
- Adgey A
- Adjei A
- Agarwal J
- Aggarwal A
- Aggarwal K
- Aggarwal R
- Agocha A
- Agraou B
- Aguirre O
- Ahmed A
- Ahmed O
- Ahsan A
- Airaksinen J
- Airoldi F
- Aji J
- Akkad H
- Akubzanova E
- Al-Ani R
- Al-Jumaily J
- Alameda J
- Albirini A
- Albuquerque A
- Albuquerque D
- Alcasena S
- Alexander J
- Alfonso F
- Ali MI
- Alings MA
- Allall O
- Allen J
- Allen RP
- Allred S
- Almeira AS
- Alonso L
- Alsagheer S
- Alshaher M
- Altschuller A
- Alvarez J
- Alvarez J
- Alvarez Y
- Alves A
- Amidon T
- Amos M
- Anaszewicz M
- Andersen M
- Andersen O
- Andersson E
- Andersson G
- Andrade G
- Andrade M
- Andrea B
- Andreou C
- Antonangelo A
- Antorrena I
- Appel K
- Arana C
- Aranda M
- Araujo J
- Arce R
- Ardito RV
- Ardito W
- Arend C
- Arias V
- Armada E
- Armstrong P
- Arnold A
- Arnold M
- Arntsen BI
- Arora P
- Aros F
- Arriagada G
- Arriagada G
- Artaecheverria J
- Arvesen K
- Arvigo L
- Ash Y
- Aske R
- Ata N
- Atar D
- Atar S
- Atassi K
- Atieh M
- Atkinson C
- Atzenhofer-Baumgartner K
- Auer J
- Aug L
- Ausen K
- Aycock G
- Aylward P
- Aylward P
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- Azize G
- Azrin M
- Azzolini P
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- Badings EA
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- Darcel I
- Darius H
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- Davidovits S
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- De Belder M
- de Carvalho Moreira R
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- De Ferrari Gaetano M.
- De Ferrari GM
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- Ă…ngman K
- Édes I
- Ă–stberg S
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2015
- Field of study
BACKGROUND: Statin therapy reduces low-density lipoprotein (LDL) cholesterol levels and the risk of cardiovascular events, but whether the addition of ezetimibe, a nonstatin drug that reduces intestinal cholesterol absorption, can reduce the rate of cardiovascular events further is not known. METHODS: We conducted a double-blind, randomized trial involving 18,144 patients who had been hospitalized for an acute coronary syndrome within the preceding 10 days and had LDL cholesterol levels of 50 to 100 mg per deciliter (1.3 to 2.6 mmol per liter) if they were receiving lipid-lowering therapy or 50 to 125 mg per deciliter (1.3 to 3.2 mmol per liter) if they were not receiving lipid-lowering therapy. The combination of simvastatin (40 mg) and ezetimibe (10 mg) (simvastatin-ezetimibe) was compared with simvastatin (40 mg) and placebo (simvastatin monotherapy). The primary end point was a composite of cardiovascular death, nonfatal myocardial infarction, unstable angina requiring rehospitalization, coronary revascularization ( 6530 days after randomization), or nonfatal stroke. The median follow-up was 6 years. RESULTS: The median time-weighted average LDL cholesterol level during the study was 53.7 mg per deciliter (1.4 mmol per liter) in the simvastatin-ezetimibe group, as compared with 69.5 mg per deciliter (1.8 mmol per liter) in the simvastatin-monotherapy group (P<0.001). The Kaplan-Meier event rate for the primary end point at 7 years was 32.7% in the simvastatin-ezetimibe group, as compared with 34.7% in the simvastatin-monotherapy group (absolute risk difference, 2.0 percentage points; hazard ratio, 0.936; 95% confidence interval, 0.89 to 0.99; P = 0.016). Rates of pre-specified muscle, gallbladder, and hepatic adverse effects and cancer were similar in the two groups. CONCLUSIONS: When added to statin therapy, ezetimibe resulted in incremental lowering of LDL cholesterol levels and improved cardiovascular outcomes. Moreover, lowering LDL cholesterol to levels below previous targets provided additional benefit