Buruli ulcer in an AIDS Patient

Buruli ulcer is a mycobacterial skin ulcer caused by Mycobacterium ulcerans, an acid-fast bacillus 3 - 6 μm long and 0.2 - 0.35 μm wide. It was first described in Australia. The name buruli ulcer derives from the Buruli district of Uganda where the disease was largely investigated. The lesions occur chiefly on the legs or arms. The diagnosis is made bacteriologically by finding the acid-fast mycobacteria in necrotic granulation tissue of the ulcer.1-4 The association between Buruli skin ulcers and HIV infection has not yet been documented although skin ulcers caused by M. chelonei have been reported in an immunocompromised child. The following case report describes a patient with HIV infection associated with a mycobacterial skin ulcer caused by M. ulcerans

Buruli ulcer : history and disease burden

A major objective of this open access book is to summarize the current status of Buruli Ulcer (BU) research for the first time. It will identify gaps in our knowledge, stimulate research and support control of the disease by providing insight into approaches for surveillance, diagnosis, and treatment of Buruli Ulcer. Book chapters will cover the history, epidemiology diagnosis, treatment and disease burden of BU and provide insight into the microbiology, genomics, transmission and virulence of Mycobacterium ulcerans. ; Supports further investigation by summarizing state of the art in the field of Buruli ulcer research Enriches understanding of epidemiology of Buruli ulcer in different geographic regions Reviews exhaustively the characteristics of Mycobacterium ulcerans diseas