11 research outputs found
Platelet-rich plasma for hip osteoarthritis: comparing the variables in production protocol and composition
Maxillary sinus lift response to platelet-rich plasma associated with autogenous bone, ceramic biphasic HA/β-TCP (70:30), or deproteinized bovine bone
Intra-articular platelet-rich plasma vs corticosteroids in the treatment of moderate knee osteoarthritis: a single-center prospective randomized controlled study with a 1-year follow up
Intra-articular platelet-rich plasma injection for knee osteoarthritis: a summary of meta-analyses
The Role of Biologic Agents in the Non-operative Management of Elbow Ulnar Collateral Ligament Injuries
Anthropogenic particle dispersions in topsoils of the Middle Nile Delta: a preliminary study on the contamination around industrial and commercial areas in Egypt
Improved outcomes after mesenchymal stem cells injections for knee osteoarthritis: results at 12-months follow-up: a systematic review of the literature
Intrauterine infusion of platelet-rich plasma for severe Asherman syndrome: a cutting-edge approach
Tendinopathy
Tendinopathy describes a complex multifaceted pathology of the tendon, characterized by pain, decline in function and reduced exercise tolerance. The most common overuse tendinopathies involve the rotator cuff tendon, medial and lateral elbow epicondyles, patellar tendon, gluteal tendons and the Achilles tendon. The prominent histological and molecular features of tendinopathy include disorganization of collagen fibres, an increase in the microvasculature and sensory nerve innervation, dysregulated extracellular matrix homeostasis, increased immune cells and inflammatory mediators, and enhanced cellular apoptosis. Although diagnosis is mostly achieved based on clinical symptoms, in some cases, additional pain-provoking tests and imaging might be necessary. Management consists of different exercise and loading programmes, therapeutic modalities and surgical interventions; however, their effectiveness remains ambiguous. Future research should focus on elucidating the key functional pathways implicated in clinical disease and on improved rehabilitation protocols