7 research outputs found
A nomeação seriada rápida em escolares com e sem queixas de problemas de aprendizagem em escola pública e particular
Reflexões sobre o Ensino de Bioética e Cuidados Paliativos nas Escolas Médicas do Estado de Minas Gerais, Brasil
Exposição a níveis de pressão sonora em sala de aula, imitanciometria e teste SSW em escolares de 3º e 4º ano do ensino fundamental
Bacharelado interdisciplinar: uma proposta inovadora na educação superior em saúde no Brasil
Avaliação da habilidade de resolução temporal, com uso do tom puro, em crianças com e sem desvio fonológico
Neuroactive compounds obtained from arthropod venoms as new therapeutic platforms for the treatment of neurological disorders
Plant products with antifungal activity. From field to biotechnology strategies
In this chapter, informations on the recent advances regarding antifungal activity of natural products obtained from plants collected directly from their natural habitat or from plant cell and organ, cultures have been reported. The biotechnological approaches could increase uniformity and predictability of the extracts and overcome problems associated with geographical, seasonal, and environmental variations. Human fungal pathogens are the cause of severe diseases associated with high morbidity and mortality. The major human fungal pathogens are Candida species, dermatophytes, Aspergillus species, and Cryptococcus neoformans. Side effects and resistance are frequently attributed to the current antifungal agents. Moreover, the treatments often require long-term therapy and are not resolving. Plants represent a source of antifungal agents, but up to date, the number of new phytochemicals reaching the market is very low. This review attempts to summarize the current status of botanical screening efforts, as well as in vitro and in vivo studies on antifungal activity of plant products. Despite the currently non-uniform regulatory framework in all the states, the plant-derived products are increasingly in demand for their effectiveness. The basic conclusion from these studies is that rigorous, well-designed clinical trials are needed to validate the effectiveness and safety of plant extracts for their use as antifungals