5 research outputs found
Fc receptor Îł-chain, a constitutive component of the IL-3 receptor, is required for IL-3-induced IL-4 production in basophils
ArticleNATURE IMMUNOLOGY. 10(2):214-222 (2009)journal articl
Immunoglobulin A: A next generation of therapeutic antibodies?
Although immunoglobulin (Ig) A is commonly recognized as the most prevalent antibody subclass at mucosal sites with an important role in mucosal defense, its potential as a therapeutic monoclonal antibody is less well known. However, IgA has multifaceted anti-, non- and pro-inflammatory functions that can be exploited for different immunotherapeutical strategies, which will be the focus of this review