27 research outputs found
The impact of licensed-knowledge attributes on the innovation performance of licensee firms: evidence from the Chinese electronic industry
The Growth of Patenting and Licensing by U.S. Universities: An assessment of the Effects of the Bayh-Dole Act of 1980
Using What You Know: Patented Knowledge in Incumbent Firms and Employee Entrepreneurship
Mindfulness Skills and Anxiety-Related Cognitive Processes Among Young Adult Daily Smokers: A Pilot Test
A self-medication hypothesis for increased vulnerability to drug abuse in prenatally restraint stressed rats
Stress-related events that occur in the perinatal period can permanently change brain and behavior of the developing individual and there is increasing evidence that early-life adversity is a contributing factor in the etiology of drug abuse and mood disorders. Neural adaptations resulting from early-life stress may mediate individual differences in novelty responsiveness and in turn contribute to drug abuse vulnerability. Prenatal restraint stress (PRS) in rats is a well-documented model of early stress known to induce long-lasting neurobiological and behavioral alterations including impaired feedback mechanisms of the HPA axis, enhanced novelty seeking, and increased sensitiveness to psychostimulants as well as anxiety/depression-like behavior. Together with the HPA axis, functional alterations of the mesolimbic dopamine system and of the metabotropic glutamate receptors system appear to be involved in the addiction-like profile of PRS rats