L’interpretazione delle performance aziendali da una prospettiva imprenditoriale. Un contributo al dibattito

il lavoro intende contribuire alla comprensione del relativo ritardo di sviluppo del sistema economico meridionale adottando una “prospettiva imprenditoriale”; vale a dire valutando l’agire delle aziende locali alla luce delle caratteristiche soggettive dei relativi imprenditori. Allo scopo, si considerano alcuni risultati di un’indagine empirica interpretati con riferimento ad un modello virtuoso di generazione dell’imprenditorialità e dei connessi fattori di sostegno o inibizione. Si tratta di una questione che implica quantomeno la comprensione dei seguenti aspetti: • le specificità imprenditoriali del contesto territoriale analizzato; • i fattori influenzanti la promozione e la disseminazione dell’imprenditorialità locale; • il livello di diffusione della cultura imprenditoriale; • i profili imprenditoriali prevalenti; • gli elementi idonei a migliorare l’efficienza e l’efficacia delle politiche imprenditorial

Turning on a dimer New insights into MLL chimeras

AbstractIn this issue of Cancer Cell, So et al. (2003) demonstrate a novel mechanism for the oncogenic activity of MLL chimeric proteins. By providing coiled-coil or other dimerization domains, the cytoplasmic partners of MLL fusion proteins donate a platform for MLL homodimerization, allowing recruitment of accessory factors needed to activate the critical downstream targets, including selected subsets of the major HOX genes

DATStats: results from 85 studies using the Drug Abuse Treatment Cost Analysis Program (DATCAP)

The Drug Abuse Treatment Cost Analysis Program (DATCAP) was developed and launched in the early 1990s to help addiction researchers and administrators estimate the economic costs of substance abuse interventions. This paper presents summary results from 85 DATCAPs completed over the past 10 years. After first grouping the DATCAPs into 9 treatment modalities, cost measures (normalized to 2001 dollars) are reported along with client caseload information. Additionally, the distribution of costs across 6 resource categories is presented for each of the treatment modalities. The average weekly economic cost per client ranged from $82 per week for outpatient drug court interventions to$1,138 per week for adolescent residential treatment. As expected, labor was overwhelmingly the most utilized resource across all modalities, ranging from 48% to 88% of total economic cost. Addiction researchers, program administrators, and policymakers now have cost estimates and resource distribution information for various treatment modalities serving diverse populations