Influence of plasma exposure on physical characteristics of thin films of SnO2 obtained from SnCl4 solutions with additives of NH4F and NH4OH

The electrical conductivity of tin dioxide is extremely sensitive to the state of the surface in the temperature range 300-800 K, at which oxidation-reduction reactions take place on its surface. Nanocrystalline films of tin dioxide are selectively sensitive to the presence of toxic gases, organic and certain biological molecules in the surrounding atmosphere [1]. SnO2-based films are also used as transparent conductive coatings [2]. To modify the properties of the films, alloying, heat treatment, plasma treatment is used

LARGE AREA HODOSCOPES FOR MUON DIAGNOSTICS OF HELIOSPHERE AND EARTH'S MAGNETOSPHERE

Muon diagnostics is a technique for remote monitoring of active processes in the heliosphere and the magnetosphere of the Earth based on the analysis of angular variations of muon flux simultaneously detected from all directions of the upper hemisphere. To carry out muon diagnostics, special detectors – muon hodoscopes – which can detect muons from any direction with good angular resolution in real-time mode are required. We discuss approaches to data analysis and the results of studies of various extra-terrestrial processes detected by means of the wide aperture URAGAN muon hodoscope

ИНВАЗИВНАЯ СТРЕПТОКОККОВАЯ ИНФЕКЦИЯ (ГРУППЫ А) МЯГКИХ ТКАНЕЙ В ХИРУРГИЧЕСКОМ СТАЦИОНАРЕ Г. МОСКВЫ

Aim. To study features and risk factors  of soft tissue's invasive streptococcal infection in surgical unit's patients: a) emm-types of the most often recovered streptococcus; b) human immune response for streptococcal antigens (streptolysin-O and the group A carbohydrate antigen); c) main patient's conditions that complicate the course of soft tissue's streptococcal infection. Patients and methods. 101 surgical unit's patients with soft tissue's infection, which group A streptococcal (GAS) nature, were examined. Emm-types were determined by comparison of emm gene sequenced part with data of CDC Streptococcus Laboratory. ASO and specific anti-group-carbohydrate IgM were measured with photometry and ELISA accordingly.  Patient’s personal data were analyzed by standard statistical programs. Results. Among 34 emm-types of all streptococcal isolates emm28 and emm64 were registered only in invasive infection.  Emm-types 1, 49, 60, 66, 77, 84, 88 were most often. Among 23 sera from invasive GAS-infection's patients, 15 (65%) were ASO-negative, 6 (26%) were ASO-low-positive, and 2 (8%) were positive, but negative for the anti-group-A-carbohydrate IgM. Conclusion. Lower levels of the humoral immune response as well as risk factors such as trauma, alcoholism, diabetes, chronic venous insufficiency contributed to development of severe forms of GAS-infection. The main streptococcal emm-types for soft tissue's invasive GAS infection in one of Moscow surgical unit's patients in 2008-2011 were registered. Цель. Изучить особенности и факторы риска развития инвазивной стрептококковой инфекции мягких тканей у пациентов хирургического стационара, определив: а)emm-типы наиболее часто высеваемых стрептококков; б)уровень иммунного ответа макроорганизма  на антигены стрептококка (стрептолизин-О, полисахарид); в)состояния, осложняющие течение стрептококковой инфекции мягких тканей. Пациенты и методы. В исследование включали пациентов хирургического стационара (101чел.), у которых выделяли стрептококки группы А. Emm-типы стрептококков устанавливали сравнением секвенированной части гена emm с данными Международного банка данных emm-типов CDC. В сыворотках определяли антитела (IgM) к полисахариду (методом ИФА) и к стрептолизину-О (спектрофотометрически). Персональные данные о больных обработаны с помощью стандартных статистических программ. Результаты. Среди идентифицированных 34-х emm-типов стрептококков 28-ой и 64-ый встречались только при инвазивной инфекции.  Кроме того, наиболее часто определяли emm-типы 1, 49, 60, 66, 77, 84, 88. Из 23 сывороток больных инвазивной формой в 15-ти (65%) отмечали низкий уровень гуморального иммунного ответа на стрептолизин-О, в 6-ти (26%)  наблюдали незначительное превышение нормального уровня, в двух случаях (8%) показатели были высокие, но при низком уровне гуморального иммунного ответа  на полисахарид.  Заключение. К факторам риска отнесены травмы, алкоголизм, диабет, хроническая венозная недостаточность нижних конечностей и низкий уровень гуморального иммунного ответа на антигены стрептококка. Определен набор emm-типов стрептококка, вызывающих  развитие инвазивных форм стрептококковой (группы А) инфекции мягких тканей у пациентов хирургического стационара г.Москвы (2008-2011годы).

Multiplicity dependence of inclusive J/psi production at midrapidity in pp collisions at root s=13 TeV

Measurements of the inclusive J/psi yield as a function of charged-particle pseudorapidity density dN(ch)/d eta in pp collisions at root s = 13 TeV with ALICE at the LHC are reported. The J/psi meson yield is measured at midrapidity (vertical bar y vertical bar <0.9) in the dielectron channel, for events selected based on the charged-particle multiplicity at midrapidity (vertical bar eta vertical bar <1) and at forward rapidity (-3.7 <eta <-1.7 and 2.8 <eta <5.1); both observables are normalized to their corresponding averages in minimum bias events. The increase of the normalized J/psi yield with normalized dN(ch)/d eta is significantly stronger than linear and dependent on the transverse momentum. The data are compared to theoretical predictions, which describe the observed trends well, albeit not always quantitatively. (C) 2020 European Organization for Nuclear Research. Published by Elsevier B.V.Peer reviewe

IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes.

GWAS have identified >200 risk loci for Inflammatory Bowel Disease (IBD). The majority of disease associations are known to be driven by regulatory variants. To identify the putative causative genes that are perturbed by these variants, we generate a large transcriptome data set (nine disease-relevant cell types) and identify 23,650 cis-eQTL. We show that these are determined by ∼9720 regulatory modules, of which ∼3000 operate in multiple tissues and ∼970 on multiple genes. We identify regulatory modules that drive the disease association for 63 of the 200 risk loci, and show that these are enriched in multigenic modules. Based on these analyses, we resequence 45 of the corresponding 100 candidate genes in 6600 Crohn disease (CD) cases and 5500 controls, and show with burden tests that they include likely causative genes. Our analyses indicate that ≥10-fold larger sample sizes will be required to demonstrate the causality of individual genes using this approach

Elliptic flow of charged particles at midrapidity relative to the spectator plane in Pb–Pb and Xe–Xe collisions

Measurements of the elliptic flow coefficient relative to the collision plane defined by the spectator neutrons v2{ SP} in collisions of Pb ions at center-of-mass energy per nucleon–nucleon pair √ 2.76 TeV and Xe ions at √ sNN = sNN =5.44 TeV are reported. The results are presented for charged particles produced at midrapidity as a function of centrality and transverse momentum for the 5–70% and 0.2–6 GeV/c ranges, respectively. The ratio between v2{ SP} and the elliptic flow coefficient relative to the participant plane v2{4}, estimated using four-particle correlations, deviates by up to 20% from unity depending on centrality. This observation differs strongly from the magnitude of the corresponding eccentricity ratios predicted by the TRENTo and the elliptic power models of initial state fluctuations that are tuned to describe the participant plane anisotropies. The differences can be interpreted as a decorrelation of the neutron spectator plane and the reaction plane because of fragmentation of the remnants from the colliding nuclei, which points to an incompleteness of current models describing the initial state fluctuations. A significant transverse momentum dependence of the ratio v2{ SP}/v2{4} is observed in all but the most central collisions, which may help to understand whether momentum anisotropies at low and intermediate transverse momentum have a common origin in initial state f luctuations. The ratios of v2{ SP} and v2{4} to the corresponding initial state eccentricities for Xe–Xe and Pb–Pb collisions at similar initial entropy density show a difference of (7.0 ±0.9)%with an additional variation of +1.8% when including RHIC data in the TRENTo parameter extraction. These observations provide new experimental constraints for viscous effects in the hydrodynamic modeling of the expanding quark–gluon plasma produced in heavy-ion collisions at the LHC

First measurement of Ωc0 production in pp collisions at s=13 TeV

The inclusive production of the charm–strange baryon 0 c is measured for the first time via its hadronic √ decay into −π+ at midrapidity (|y| &lt;0.5) in proton–proton (pp) collisions at the centre-of-mass energy s =13 TeV with the ALICE detector at the LHC. The transverse momentum (pT) differential cross section multiplied by the branching ratio is presented in the interval 2 &lt; pT &lt; 12 GeV/c. The pT dependence of the 0 c-baryon production relative to the prompt D0-meson and to the prompt 0 c-baryon production is compared to various models that take different hadronisation mechanisms into consideration. In the measured pT interval, the ratio of the pT-integrated cross sections of 0 c and prompt + c baryons multiplied by the −π+ branching ratio is found to be larger by a factor of about 20 with a significance of about 4σ when compared to e+e− collisions

Genderlect as a linguistic and cultural phenomenon: Issues of communication competence study [La perspectiva de género como fenómeno lingüístico y cultural: Cuestiones de estudio de la competencia comunicativa]

Issues related to the sociocultural phenomenon reflecting the features of male and female speech – gender dialect or genderlect – are discussed. It is shown that men and women often use different communicative styles, both in verbal communication and in network communications, which makes it possible to consider genderlect as a relevant linguistic cultural phenomenon. A comparative analysis of linguistic gender manifestations in network communications of Francophones from Quebec, Maghreb and French society is carried out. © 2018, Universidad del Zulia. All rights reserved

Intraovarian autoplasmotherapy in patients with diminished ovarian reserve

Objective. To evaluate the efficacy of Intraovarian autoplasmotherapy (platelet-rich plasma/PRP) in the activation of ovarian function in patients with diminished ovarian reserve and “poor” response in the in vitro fertilization (IVF) cycles, as well as its influence on the quality of life. Patients and methods. A total of 120 patients with diminished ovarian reserve and a history of IVF cycle failure who refused to use donor oocytes were included in the study. All patients underwent intraovarian PRP therapy based on the proprietary technology. The quality of life, the ovarian function, and the results of the embryo stage in the IVF cycle were monitored for 6 months. Results. The conducted study demonstrates a positive effect of intraovarian PRP therapy on the functional state of the ovaries and on the results of the embryo stage in IVF in the cohort of patients with diminished ovarian reserve and “poor” response in previous unsuccessful IVF cycles. The findings also indicate changes in the quality of life, an improvement in sexual function, and positive dynamics in the emotional state. Conclusion. Intraovarian PRP therapy allows patients with infertility and diminished ovarian reserve to avoid using donor oocytes and to obtain their own genetic material. This technology has a positive effect on the quality of life, having a certain anti-age effect in all groups of examined women, the duration of which has yet to be clarified. © 2021, Dynasty Publishing House. All rights reserved