Comparison of two jejunal anastomosis techniques in dogs treated preoperatively with dexamethasone

The aim of this study was to evaluate effects of steroidal antiinflammatory drugs that given before surgery on two intestinal anastomosis techniques in dogs. Thirty-two adult local breed dogs were equally and randomly divided into 2 groups: group 1: consist of 16 dogs underwent apposition End-To-End jejunal anastomosis using simple interrupted suture technique and divided this into 2 subgroups: subgroup A: consist of 8 dogs treated preoperatively for 15 days with dexamethasone at a dose of (0.1ml/kg) given I/M. Subgroup B: control group consists of 8 dogs not treated with dexamethasone. Group 2: consist of 16 dogs underwent inverted End-To-End jejunal anastomosis using continuous Lumbert suture pattern and divided this into 2 subgroups: subgroup A: consists of 8 dogs treated preoperatively for 15 days with dexamethasone at a dose of (0.1ml/kg) given I/M. Subgroup B: control group consist of 8 dogs not treated with dexamethasone. The result showed the adhesion at anastomosis site with omentum was more severe in the group one when compared with the group two. The degree of stenosis rate was lower in group one after 7 days of operation (22.7±8.2) while the degree of stenosis rate was higher in the group two after 15 days (54.9±4.1). The anastomotic bursting pressure was significantly lower in the all steroidal subgroups at 7 and 15 days compared with the control subgroups

Evaluation healing of jejunal anastomosis in preoperative dexamethasone treated dogs

The objective of this study is to evaluate the healing process of jejunal anastomosis by the aid of histopathology and measurement of bursting pressure of anastomosis site in thirty two adult preoperatively with dexamethasone. The animals were randomly divided into 2 equal groups: Group 1: consists of 16 dogs underwent apposition end-to-end jejunal anastomosis using simple interrupted suture technique which in turn divided into 2 subgroups: subgroup A: consists of 8 dogs treated preoperatively for 15 days with dexamethasone at a dose of (0.2mg/kg) given I/M. Subgroup B: control group consists of 8 dogs not treated with dexamethasone. Group 2: consists of 16 dogs underwent inverted end-to-end jejunal anastomosis using continuous Lembert suture pattern that also divided into 2 subgroups: subgroup A: consists of 8 dogs treated preoperatively for 15 days with dexamethasone at a dose of (0.2mg/kg) given I/M. subgroup B: control group consists of 8 dogs not treated with dexamethasone. The result of bursting pressure measurement showed higher tensile strength in the control groups (445±9.6) in comparison with the steroidal groups (255±25.3) for both techniques. The histopathological study showed that the healing was good in all groups but the rupture that occur due to shedding the pressure lead to non discrimination between which is better in terms of healing. Massonʼs trichrome showed that collagen content of subgroups taking dexamethasone was lower than that of subgroups not treated with dexamethasone