10 research outputs found

    The research of the electric arc movement of direct current arc gas heater

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    © 2020 Published under licence by IOP Publishing Ltd. This article deals with experimental definition of the electric arc moving speed and develops relation of current strength change at interelectrode gap 2, 3 and 4 mm considering different consumption of orifice gas. Shadow photographs of the electric arc and traces on the electrodes have been also provided

    The study of electric arc travel velocity properties in circular plasmatron

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    This article presents the results of calculated electric arc travel velocity in a circular plasmatron. The calculation of the electric arc travel velocity should consider a set of parameters and factors from the current strength to running inductance of parallel electrodes

    Modeling of the rheological and thermophysical properties of food materials when frying in a deep fryer

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    © 2020 Trans Tech Publications Ltd, Switzerland. The deep-frying is one of the most widespread technologies for the production of culinary products and one of the foundations of the global food industry. In this connection, the researchers are faced with the continuous task of stable improve product quality, thermal efficiency and operating characteristics of equipment which, including, can be solved by increasing the precision of setting the thermal regime of heating the frying oil. In turn, the thermal mode of heating the frying oil directly affects its quality and the quality of the final product. It is known that for some media the macroscopic state at a given time depends on their state at earlier time (the phenomenon of memory). These work deals with the modeling of thermophysical processes in frying oil on the basis of the theory of materials with memory are considered. The influence of the oil degradation degree on the changes in its viscosity and convective heat transfer coefficient is shown. As a result of the analysis of the data, formulas for the corresponding corrections are derived. The conclusion is drawn that for the management of the quality of food requires data analysis when developing a mathematical model of the process

    Calculation of stresses in sleeved mandrels for tube rolling

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    Translated from Russian (Izv. Vyssh. Uchebn. Zaved., Chern. Metall. 1987 (1) p. 62-68)SIGLEAvailable from British Library Document Supply Centre- DSC:5828.4(M--37311)T / BLDSC - British Library Document Supply CentreGBUnited Kingdo

    Improvement of operating temperature conditions of Pilger mill mandrels

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    Translated from Russian (Izv. Vyssh. Uchebn. Zaved., Chern. Metall. 1985 (7) p. 78-80)Available from British Library Document Supply Centre- DSC:5828.4(M--36581)T / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo

    Structure impact on photodynamic therapy and cellular contrasting functions of colloids constructed from dimeric Au(I) complex and hexamolybdenum clusters

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    Electrostatically driven self-assembly of [Au2L2]2+ (L is cyclic PNNP ligand) with [{Mo6I8}(L')6]2− (L' = I−, CH3COO−) in aqueous solutions is introduced as facile route for combination of therapeutic and cellular contrasting functions within heterometallic colloids (Mo6-Au2). The nature of L' affects the size and aggregation behavior of crystalline Mo6-Au2 aggregates, which in turn affect the luminescence of the cluster units incorporated into Mo6-Au2 colloids. The spin trap facilitated electron spin resonance spectroscopy technique indicates that the level of ROS generated by Mo6-Au2 colloids is also affected by their size. Both (L' = I−, CH3COO−) Mo6-Au2 colloids undergo cell internalization, which is enhanced by their assembly with poly-DL-lysine (PL) for L' = CH3COO−, but remains unchanged for L' = I−. The colloids PL-Mo6-Au2 (L' = CH3COO−) are visualized as huge crystalline aggregates both outside and inside the cell cytoplasm by confocal microscopy imaging of the incubated cells, while the smaller sized (30–50 nm) PL-Mo6-Au2 (L' = I−) efficiently stain the cell nuclei. Quantitative colocalization analysis of PL-Mo6-Au2 (L' = CH3COO−) in lysosomal compartments points to the fast endo-lysosomal escape of the colloids followed by their intracellular aggregation. The cytotoxicity of PL-Mo6-Au2 differs from that of Mo6 and Au2 blocks, predominantly acting through apoptotic pathway. The photodynamic therapeutic effect of the PL-Mo6-Au2 colloids on the cancer cells correlates with their intracellular trafficking and aggregation

    Mitochondria-targeted mesoporous silica nanoparticles noncovalently modified with triphenylphosphonium cation: Physicochemical characteristics, cytotoxicity and intracellular uptake

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    Novel nanocomposite system based on mesoporous silica nanoparticles (MSNs) noncovalently modified with hexadecyltriphenylphosphonium bromide (HTPPB) has been prepared, thoroughly characterized and used for encapsulation of model cargo Rhodamine B (RhB). The high encapsulation efficacy of this dye by HTPPB-modified mesoporous particles was demonstrated by spectrophotometry and thermography techniques. The bioavailability of MSN@HTPPB was testified. Cytotoxicity assay revealed that a marked suppression of M−HeLa cancer cells (epithelioid carcinoma of the cervix) occurs at concentration of 0.06 μg/mL, while the higher viability of Chang liver normal cell line was preserved in the concentration range of 0.98–0.06 μg/mL. Hemolysis assay demonstrated that only 2% of red blood cells are destructed at ~ 30 μg/mL concentration. This allows us to select the most harmless compositions based on MSN@HTPPB with minimal side effects toward normal cells and recommend them for the development of antitumor formulations. Fluorescence microscopy technique testified satisfactory penetration of HTPPB-modified carriers into M−HeLa cells. Importantly, modification of the MSN with HTPPB is shown to promote efficient delivery to mitochondria. To the best of our knowledge, it is one of the first successful examples of noncovalent surface modification of the MSNs with lipophilic phosphonium cation that improves targeted delivery of loads to mitochondria
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