Inhomogeneous Neutrino Degeneracy and Big Bang Nucleosynthesis

We examine Big Bang nucleosynthesis (BBN) in the case of inhomogenous neutrino degeneracy, in the limit where the fluctuations are sufficiently small on large length scales that the present-day element abundances are homogeneous. We consider two representive cases: degeneracy of the electron neutrino alone, and equal chemical potentials for all three neutrinos. We use a linear programming method to constrain an arbitrary distribution of the chemical potentials. For the current set of (highly-restrictive) limits on the primordial element abundances, homogeneous neutrino degeneracy barely changes the allowed range of the baryon-to-photon ratio. Inhomogeneous degeneracy allows for little change in the lower bound on the baryon-to-photon ratio, but the upper bound in this case can be as large as 1.1 \times 10^{-8} (only electron neutrino degeneracy) or 1.0 \times 10^{-9} (equal degeneracies for all three neutrinos). For the case of inhomogeneous neutrino degeneracy, we show that there is no BBN upper bound on the neutrino energy density, which is bounded in this case only by limits from structure formation and the cosmic microwave background.Comment: 6 pages, no figure

Big Bang Nucleosynthesis with Gaussian Inhomogeneous Neutrino Degeneracy

We consider the effect of inhomogeneous neutrino degeneracy on Big Bang nucleosynthesis for the case where the distribution of neutrino chemical potentials is given by a Gaussian. The chemical potential fluctuations are taken to be isocurvature, so that only inhomogeneities in the electron chemical potential are relevant. Then the final element abundances are a function only of the baryon-photon ratio $\eta$, the effective number of additional neutrinos $\Delta N_\nu$, the mean electron neutrino degeneracy parameter $\bar \xi$, and the rms fluctuation of the degeneracy parameter, $\sigma_\xi$. We find that for fixed $\eta$, $\Delta N_\nu$, and $\bar \xi$, the abundances of helium-4, deuterium, and lithium-7 are, in general, increasing functions of $\sigma_\xi$. Hence, the effect of adding a Gaussian distribution for the electron neutrino degeneracy parameter is to decrease the allowed range for $\eta$. We show that this result can be generalized to a wide variety of distributions for $\xi$.Comment: 9 pages, 3 figures, added discussion of neutrino oscillations, altered presentation of figure

Large lepton asymmetry from Q-balls

We propose a scenario which can explain large lepton asymmetry and small baryon asymmetry simultaneously. Large lepton asymmetry is generated through Affleck-Dine (AD) mechanism and almost all the produced lepton numbers are absorbed into Q-balls (L-balls). If the lifetime of the L-balls is longer than the onset of electroweak phase transition but shorter than the epoch of big bang nucleosynthesis (BBN), the large lepton asymmetry in the L-balls is protected from sphaleron effects. On the other hand, small (negative) lepton numbers are evaporated from the L-balls due to thermal effects, which are converted into the observed small baryon asymmetry by virtue of sphaleron effects. Large and positive lepton asymmetry of electron type is often requested from BBN. In our scenario, choosing an appropriate flat direction in the minimal supersymmetric standard model (MSSM), we can produce positive lepton asymmetry of electron type but totally negative lepton asymmetry.Comment: 10 pages, 3 figures, ReVTeX

Electroweak phase diagram at finite lepton number density

We study the thermodynamics of the electroweak theory at a finite lepton number density. The phase diagram of the theory is calculated by relating the full 4-dimensional theory to a 3-dimensional effective theory which has been previously solved using nonperturbative methods. It is seen that the critical temperature increases and the value of the Higgs boson mass at which the first order phase transition line ends decreases with increasing leptonic chemical potential.Comment: 16 pages, 14 figures, RevTex4, v2: references added, minor corrections, v3: small changes, references added, published in Phys. Rev.

A methodology for determining amino-acid substitution matrices from set covers

We introduce a new methodology for the determination of amino-acid substitution matrices for use in the alignment of proteins. The new methodology is based on a pre-existing set cover on the set of residues and on the undirected graph that describes residue exchangeability given the set cover. For fixed functional forms indicating how to obtain edge weights from the set cover and, after that, substitution-matrix elements from weighted distances on the graph, the resulting substitution matrix can be checked for performance against some known set of reference alignments and for given gap costs. Finding the appropriate functional forms and gap costs can then be formulated as an optimization problem that seeks to maximize the performance of the substitution matrix on the reference alignment set. We give computational results on the BAliBASE suite using a genetic algorithm for optimization. Our results indicate that it is possible to obtain substitution matrices whose performance is either comparable to or surpasses that of several others, depending on the particular scenario under consideration

Do neutrino flavor oscillations forbid large lepton asymmetry of the universe ?

It is shown that hypothetical neutrino-majoron coupling can suppress neutrino flavor oscillations in the early universe, in contrast to the usual weak interaction case. This reopens a window for a noticeable cosmological lepton asymmetry which is forbidden for the large mixing angle solution in the case of standard interactions of neutrinos.Comment: 23pages, 7 figures, the version accepted to Nuclear Physics B; a few explanatory comments and one reference are adde

Deep sequencing of the vaginal microbiota of women with HIV

Background:Women living with HIV and co-infected with bacterial vaginosis (BV) are at higher risk for transmitting HIV to a partner or newborn. It is poorly understood which bacterial communities constitute BV or the normal vaginal microbiota among this population and how the microbiota associated with BV responds to antibiotic treatment. Methods and Findings: The vaginal microbiota of 132 HIV positive Tanzanian women, including 39 who received metronidazole treatment for BV, were profiled using Illumina to sequence the V6 region of the 16S rRNA gene. Of note, Gardnerella vaginalis and Lactobacillus iners were detected in each sample constituting core members of the vaginal microbiota. Eight major clusters were detected with relatively uniform microbiota compositions. Two clusters dominated by L. iners or L. crispatus were strongly associated with a normal microbiota. The L. crispatus dominated microbiota were associated with low pH, but when L. crispatus was not present, a large fraction of L. iners was required to predict a low pH. Four clusters were strongly associated with BV, and were dominated by Prevotella bivia, Lachnospiraceae, or a mixture of different species. Metronidazole treatment reduced the microbial diversity and perturbed the BV-associated microbiota, but rarely resulted in the establishment of a lactobacilli-dominated microbiota. Conclusions: Illumina based microbial profiling enabled high though-put analyses of microbial samples at a high phylogenetic resolution. The vaginal microbiota among women living with HIV in Sub-Saharan Africa constitutes several profiles associated with a normal microbiota or BV. Recurrence of BV frequently constitutes a different BV-associated profile than before antibiotic treatment

BBN bounds on active-sterile neutrino mixing

Nucleosynthesis restrictions on mixing of active neutrinos with possible sterile ones are obtained with the account of experimentally determined mixing between all active neutrinos. The earlier derived bounds, valid in the absence of active-active mixing, are reanalyzed and significant difference is found in the resonance case. The results are obtained both analytically and numerically by solution of complete system of integro-differential kinetic equations. A good agreement between analytical and numerical approaches is demonstrated. A role of possibly large cosmological lepton asymmetry is discussed.Comment: 38 pages, 10 figure

Transient domain walls and lepton asymmetry in the Left-Right symmetric model

It is shown that the dynamics of domain walls in Left-Right symmetric models, separating respective regions of unbroken SU(2)_L and SU(2)_R in the early universe, can give rise to baryogenesis via leptogenesis. Neutrinos have a spatially varying complex mass matrix due to CP-violating scalar condensates in the domain wall. The motion of the wall through the plasma generates a flux of lepton number across the wall which is converted to a lepton asymmetry by helicity-flipping scatterings. Subsequent processing of the lepton excess by sphalerons results in the observed baryon asymmetry, for a range of parameters in Left-Right symmetric models.Comment: v2 version accepted for publication in Phys. Rev. D. Discussion in Introduction and Conclusion sharpened. Equation (12) corrected. 16 pages, 3 figure files, RevTeX4 styl

Panspermia, Past and Present: Astrophysical and Biophysical Conditions for the Dissemination of Life in Space

Astronomically, there are viable mechanisms for distributing organic material throughout the Milky Way. Biologically, the destructive effects of ultraviolet light and cosmic rays means that the majority of organisms arrive broken and dead on a new world. The likelihood of conventional forms of panspermia must therefore be considered low. However, the information content of dam-aged biological molecules might serve to seed new life (necropanspermia).Comment: Accepted for publication in Space Science Review