8 research outputs found
Π‘ΡΡΡΠΊΡΡΡΠ½ΡΠ΅ Π²ΠΎΠ·ΡΠ°ΡΡΠ½ΡΠ΅ ΠΏΡΠ΅ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΡ Π½Π΅ΠΉΡΠΎΠ½Π½ΡΡ Π³ΡΡΠΏΠΏΠΈΡΠΎΠ²ΠΎΠΊ ΠΊΠΎΡΡ Π±ΠΎΠ»ΡΡΠΎΠ³ΠΎ ΠΌΠΎΠ·Π³Π° ΠΈ ΠΌΠΎΠ·ΠΆΠ΅ΡΠΊΠ° Ρ Π΄Π΅ΡΠ΅ΠΉ
Objective - the study of age-related changes in neural groups of the cerebral cortex and cerebellar cortex in the process of upward ontogenesis. Material and methods. The work was done on post-mortal material (75 left cerebral hemispheres, 62 cerebellum) obtained from children from birth to 12 years old who died as a result of injuries without damage to the brain. Using computer morphometry on the Nissl stained frontal histological sections of the cerebral cortex taken in layer III of fields 8, 6oΡ and 37ac, as well as in the granular layer of the paramedian lobule of the cerebellar cortex (H VII B), the area of the neural group on the section and the total area of neurons were measured as part of a grouping. Quantitative data analysis was carried out using variation statistics in annual intervals. Results. In children from birth to 12 years, in the dynamics of developmental changes in the microstructure of the cerebral and cerebellar cortical zones associated with visual-spatial perception, 4 stages of quantitative changes in the cluster (ensemble) organization of the cortex are distinguished: I - from birth to the end of 1 year of life, II - from 1 to the end of 2 years, III - from 3 to 5-6 years, IV - from 5-6 to 8-9 years. In the cerebellum cortex, significant changes in the structure of neural clusters are observed by the end of 1 year of life, by 3 and by 5-6 years. Structural changes in neural groups differ in terms and intensity in each of the studied fields. Conclusion. The sizes of neural clusters in the microstructure of the cerebral and cerebellar cortex are informative indicators for identifying the stages of significant age-related transformations in different zones of the human cortical formations in postnatal ontogenesis, and can be recommended for use in comparative anatomical and clinical studies.Π¦Π΅Π»Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ - ΠΈΠ·ΡΡΠ΅Π½ΠΈΠ΅ Π²ΠΎΠ·ΡΠ°ΡΡΠ½ΡΡ
ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΉ Π½Π΅ΠΉΡΠΎΠ½Π½ΡΡ
Π³ΡΡΠΏΠΏΠΈΡΠΎΠ²ΠΎΠΊ (ΠΊΠ»Π°ΡΡΠ΅ΡΠΎΠ²) ΠΊΠΎΡΡ Π±ΠΎΠ»ΡΡΠΎΠ³ΠΎ ΠΌΠΎΠ·Π³Π° ΠΈ ΠΊΠΎΡΡ ΠΌΠΎΠ·ΠΆΠ΅ΡΠΊΠ° ΡΠ΅Π»ΠΎΠ²Π΅ΠΊΠ° Π² ΠΏΡΠΎΡΠ΅ΡΡΠ΅ ΠΎΠ½ΡΠΎΠ³Π΅Π½Π΅Π·Π°. ΠΠ°ΡΠ΅ΡΠΈΠ°Π» ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. Π Π°Π±ΠΎΡΠ° Π²ΡΠΏΠΎΠ»Π½Π΅Π½Π° Π½Π° ΠΏΠΎΡΡΠΌΠΎΡΡΠ°Π»ΡΠ½ΠΎΠΌ ΠΌΠ°ΡΠ΅ΡΠΈΠ°Π»Π΅ (75 Π»Π΅Π²ΡΡ
ΠΏΠΎΠ»ΡΡΠ°ΡΠΈΠΉ Π±ΠΎΠ»ΡΡΠΎΠ³ΠΎ ΠΌΠΎΠ·Π³Π°, 62 ΠΌΠΎΠ·ΠΆΠ΅ΡΠΊΠ°), ΠΏΠΎΠ»ΡΡΠ΅Π½Π½ΠΎΠΌ ΠΎΡ Π΄Π΅ΡΠ΅ΠΉ Π² Π²ΠΎΠ·ΡΠ°ΡΡΠ΅ ΠΎΡ ΡΠΎΠΆΠ΄Π΅Π½ΠΈΡ Π΄ΠΎ 12 Π»Π΅Ρ, ΡΠΌΠ΅ΡΡΠΈΡ
Π² ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ΅ ΡΡΠ°Π²ΠΌ Π±Π΅Π· ΠΏΠΎΠ²ΡΠ΅ΠΆΠ΄Π΅Π½ΠΈΠΉ Π³ΠΎΠ»ΠΎΠ²Π½ΠΎΠ³ΠΎ ΠΌΠΎΠ·Π³Π°. Π‘ ΠΏΠΎΠΌΠΎΡΡΡ ΠΊΠΎΠΌΠΏΡΡΡΠ΅ΡΠ½ΠΎΠΉ ΠΌΠΎΡΡΠΎΠΌΠ΅ΡΡΠΈΠΈ Π½Π° ΠΎΠΊΡΠ°ΡΠ΅Π½Π½ΡΡ
ΠΏΠΎ ΠΠΈΡΡΠ»Ρ ΡΡΠΎΠ½ΡΠ°Π»ΡΠ½ΡΡ
Π³ΠΈΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΡΠ΅Π·Π°Ρ
ΠΊΠΎΡΡ Π±ΠΎΠ»ΡΡΠΎΠ³ΠΎ ΠΌΠΎΠ·Π³Π° Π½Π° ΡΡΠΎΠ²Π½Π΅ ΡΠ»ΠΎΡ III ΠΏΠΎΠ»Π΅ΠΉ 8, 6ΠΎΡ ΠΈ 37Π°Ρ, Π° ΡΠ°ΠΊΠΆΠ΅ Π² Π·Π΅ΡΠ½ΠΈΡΡΠΎΠΌ ΡΠ»ΠΎΠ΅ ΠΏΠ°ΡΠ°ΠΌΠ΅Π΄ΠΈΠ°Π½Π½ΠΎΠΉ Π΄ΠΎΠ»ΡΠΊΠΈ ΠΊΠΎΡΡ ΠΌΠΎΠ·ΠΆΠ΅ΡΠΊΠ° (H VII B) ΠΈΠ·ΠΌΠ΅ΡΡΠ»ΠΈ ΠΏΠ»ΠΎΡΠ°Π΄Ρ Π½Π΅ΠΉΡΠΎΠ½Π½ΠΎΠΉ Π³ΡΡΠΏΠΏΠΈΡΠΎΠ²ΠΊΠΈ Π½Π° ΡΡΠ΅Π·Π΅ ΠΈ ΡΡΠΌΠΌΠ°ΡΠ½ΡΡ ΠΏΠ»ΠΎΡΠ°Π΄Ρ Π½Π΅ΠΉΡΠΎΠ½ΠΎΠ² Π² ΡΠΎΡΡΠ°Π²Π΅ Π³ΡΡΠΏΠΏΠΈΡΠΎΠ²ΠΊΠΈ. ΠΠ½Π°Π»ΠΈΠ· ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΡ
Π΄Π°Π½Π½ΡΡ
ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΠ»ΠΈ Ρ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ΠΌ Π²Π°ΡΠΈΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΉ ΡΡΠ°ΡΠΈΡΡΠΈΠΊΠΈ Π² Π³ΠΎΠ΄ΠΎΠ²ΡΡ
ΠΈΠ½ΡΠ΅ΡΠ²Π°Π»Π°Ρ
. Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. Π£ Π΄Π΅ΡΠ΅ΠΉ ΠΎΡ ΡΠΎΠΆΠ΄Π΅Π½ΠΈΡ Π΄ΠΎ 12 Π»Π΅Ρ Π² Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΠ΅ ΠΏΠΎΡΡΠ½Π°ΡΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΠΌΠΈΠΊΡΠΎΡΡΡΡΠΊΡΡΡΡ Π·ΠΎΠ½ Π½Π΅ΠΎΠΊΠΎΡΡΠ΅ΠΊΡΠ° Π±ΠΎΠ»ΡΡΠΎΠ³ΠΎ ΠΌΠΎΠ·Π³Π°, ΡΠ²ΡΠ·Π°Π½Π½ΡΡ
ΡΠΎ Π·ΡΠΈΡΠ΅Π»ΡΠ½ΠΎ-ΠΏΡΠΎΡΡΡΠ°Π½ΡΡΠ²Π΅Π½Π½ΡΠΌ Π²ΠΎΡΠΏΡΠΈΡΡΠΈΠ΅ΠΌ, Π²ΡΠ΄Π΅Π»Π΅Π½Ρ 4 ΡΡΠ°ΠΏΠ° ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΡ
ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΉ ΠΊΠ»Π°ΡΡΠ΅ΡΠ½ΠΎΠΉ (Π°Π½ΡΠ°ΠΌΠ±Π»Π΅Π²ΠΎΠΉ) ΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΈΠΈ ΠΊΠΎΡΡ: I - ΠΎΡ ΡΠΎΠΆΠ΄Π΅Π½ΠΈΡ Π΄ΠΎ ΠΊΠΎΠ½ΡΠ° 1-Π³ΠΎ Π³ΠΎΠ΄Π° ΠΆΠΈΠ·Π½ΠΈ, II - ΠΎΡ 1-Π³ΠΎ Π΄ΠΎ ΠΊΠΎΠ½ΡΠ° 2-Π³ΠΎ Π³ΠΎΠ΄Π°, III - ΠΎΡ 3 Π΄ΠΎ 5-6 Π»Π΅Ρ, IV - ΠΎΡ 5-6 Π΄ΠΎ 8-9 Π»Π΅Ρ. Π ΠΊΠΎΡΠ΅ ΠΌΠΎΠ·ΠΆΠ΅ΡΠΊΠ° Π·Π½Π°ΡΠΈΠΌΡΠ΅ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΡ Π² ΡΡΡΡΠΊΡΡΡΠ΅ Π½Π΅ΠΉΡΠΎΠ½Π½ΡΡ
ΠΊΠ»Π°ΡΡΠ΅ΡΠΎΠ² ΠΎΡΠΌΠ΅ΡΠ°ΡΡΡΡ ΠΊ ΠΊΠΎΠ½ΡΡ 1-Π³ΠΎ Π³ΠΎΠ΄Π° ΠΆΠΈΠ·Π½ΠΈ, ΠΊ 3 ΠΈ ΠΊ 5-6 Π³ΠΎΠ΄Π°ΠΌ. Π‘ΡΡΡΠΊΡΡΡΠ½ΡΠ΅ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΡ Π½Π΅ΠΉΡΠΎΠ½Π½ΡΡ
Π³ΡΡΠΏΠΏΠΈΡΠΎΠ²ΠΎΠΊ ΠΎΡΠ»ΠΈΡΠ°ΡΡΡΡ ΠΏΠΎ ΡΡΠΎΠΊΠ°ΠΌ ΠΈ ΠΈΠ½ΡΠ΅Π½ΡΠΈΠ²Π½ΠΎΡΡΠΈ Π² ΠΊΠ°ΠΆΠ΄ΠΎΠΌ ΠΈΠ· ΠΈΠ·ΡΡΠ΅Π½Π½ΡΡ
ΠΏΠΎΠ»Π΅ΠΉ. ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. Π Π°Π·ΠΌΠ΅ΡΡ Π½Π΅ΠΉΡΠΎΠ½Π½ΡΡ
ΠΊΠ»Π°ΡΡΠ΅ΡΠΎΠ² ΠΊΠΎΡΠΊΠΎΠ²ΡΡ
ΡΠΎΡΠΌΠ°ΡΠΈΠΉ ΡΠ²Π»ΡΡΡΡΡ ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠ²Π½ΡΠΌΠΈ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΡΠΌΠΈ Π΄Π»Ρ Π²ΡΡΠ²Π»Π΅Π½ΠΈΡ ΡΡΠ°ΠΏΠΎΠ² Π·Π½Π°ΡΠΈΠΌΡΡ
Π²ΠΎΠ·ΡΠ°ΡΡΠ½ΡΡ
ΠΏΡΠ΅ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΠΉ Π² ΡΠ°Π·Π»ΠΈΡΠ½ΡΡ
Π·ΠΎΠ½Π°Ρ
ΠΊΠΎΡΡ Π±ΠΎΠ»ΡΡΠΎΠ³ΠΎ ΠΌΠΎΠ·Π³Π° ΠΈ ΠΌΠΎΠ·ΠΆΠ΅ΡΠΊΠ° ΡΠ΅Π»ΠΎΠ²Π΅ΠΊΠ° Π² ΠΏΠΎΡΡΠ½Π°ΡΠ°Π»ΡΠ½ΠΎΠΌ ΠΎΠ½ΡΠΎΠ³Π΅Π½Π΅Π·Π΅ ΠΈ ΠΌΠΎΠ³ΡΡ Π±ΡΡΡ ΡΠ΅ΠΊΠΎΠΌΠ΅Π½Π΄ΠΎΠ²Π°Π½Ρ Π΄Π»Ρ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΡ Π² ΡΡΠ°Π²Π½ΠΈΡΠ΅Π»ΡΠ½ΠΎ-Π°Π½Π°ΡΠΎΠΌΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΈ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡΡ
On the existence of transition layers of spike type in reaction-diffusion-convection equations
We investigate steady state solutions to a class of systems of reaction-diffusion-convection equations with small diffusion and small convection, and which depend on one space variable. Our main concern is to prove the existence of a solution with an interior layer of spike type for higher order systems without taking into consideration the influence of boundary conditions. To this end we combine two methods of the theory of singular perturbations: the method of integral manifolds and the method of boundary layer functions. (orig.)Available from TIB Hannover: RR 5549(170)+a / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman