433 research outputs found

    A Renormalization Group Approach to Relativistic Cosmology

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    We discuss the averaging hypothesis tacitly assumed in standard cosmology. Our approach is implemented in a "3+1" formalism and invokes the coarse graining arguments, provided and supported by the real-space Renormalization Group (RG) methods. Block variables are introduced and the recursion relations written down explicitly enabling us to characterize the corresponding RG flow. To leading order, the RG flow is provided by the Ricci-Hamilton equations studied in connection with the geometry of three-manifolds. The properties of the Ricci-Hamilton flow make it possible to study a critical behaviour of cosmological models. This criticality is discussed and it is argued that it may be related to the formation of sheet-like structures in the universe. We provide an explicit expression for the renormalized Hubble constant and for the scale dependence of the matter distribution. It is shown that the Hubble constant is affected by non-trivial scale dependent shear terms, while the spatial anisotropy of the metric influences significantly the scale-dependence of the matter distribution.Comment: 57 pages, LaTeX, 15 pictures available on request from the Author

    Expansion du pin d'Alep. Rôle des processus allélopathiques dans la dynamique successionnelle.

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    L'objet de cet article est de montrer quel peut être le rôle des processus allélopathiques dans le cas d'espèces ligneuses constituant des éléments majeurs des successions secondaires en région méditerranéenne. Les études confirment les propriétés allélopathiques du pin d'Alep, propriétés qu'il faut nuancer en fonction des stades dynamiques et en fonction des sources d'allélochimiques (pluviolessivats ou exsudats racinaires). Enfin la mise en évidence de phénomènes d'autotoxicité amène une réflexion sur les régulations de la dynamique populationnelle de ce pin et sur ses conséquences sur la succession végétale

    About curvature, conformal metrics and warped products

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    We consider the curvature of a family of warped products of two pseduo-Riemannian manifolds (B,gB)(B,g_B) and (F,gF)(F,g_F) furnished with metrics of the form c2gBw2gFc^{2}g_B \oplus w^2 g_F and, in particular, of the type w2μgBw2gFw^{2 \mu}g_B \oplus w^2 g_F, where c,w ⁣:B(0,)c, w \colon B \to (0,\infty) are smooth functions and μ\mu is a real parameter. We obtain suitable expressions for the Ricci tensor and scalar curvature of such products that allow us to establish results about the existence of Einstein or constant scalar curvature structures in these categories. If (B,gB)(B,g_B) is Riemannian, the latter question involves nonlinear elliptic partial differential equations with concave-convex nonlinearities and singular partial differential equations of the Lichnerowicz-York type among others.Comment: 32 pages, 3 figure

    Surveillance of multiple congenital anomalies; searching for new associations

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    \ua9 2023, The Author(s).Many human teratogens are associated with a spectrum of congenital anomalies rather than a single defect, and therefore the identification of congenital anomalies occurring together more frequently than expected may improve the detection of teratogens. Thirty-two EUROCAT congenital anomaly registries covering 6,599,765 births provided 123,566 cases with one or more major congenital anomalies (excluding chromosomal and genetic syndromes) for the birth years 2008–2016. The EUROCAT multiple congenital anomaly algorithm identified 8804 cases with two or more major congenital anomalies in different organ systems, that were not recognized as part of a syndrome or sequence. For each pair of anomalies, the odds of a case having both anomalies relative to having only one anomaly was calculated and the p value was estimated using a two-sided Fisher’s exact test. The Benjamini–Hochberg procedure adjusted p values to control the false discovery rate and pairs of anomalies with adjusted p values < 0.05 were identified. A total of 1386 combinations of two anomalies were analyzed. Out of the 31 statistically significant positive associations identified, 20 were found to be known associations or sequences already described in the literature and 11 were considered “potential new associations” by the EUROCAT Coding and Classification Committee. After a review of the literature and a detailed examination of the individual cases with the anomaly pairs, six pairs remained classified as new associations. In summary, systematically searching for congenital anomalies occurring together more frequently than expected using the EUROCAT database is worthwhile and has identified six new associations that merit further investigation

    Prevalence of Esophageal Atresia among 18 International Birth Defects Surveillance Programs

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    BACKGROUND: The prevalence of esophageal atresia (EA) has been shown to vary across different geographical settings. Investigation of geographical differences may provide an insight into the underlying etiology of EA. METHODS: The study population comprised infants diagnosed with EA during 1998 to 2007 from 18 of the 46 birth defects surveillance programs, members of the International Clearinghouse for Birth Defects Surveillance and Research. Total prevalence per 10,000 births for EA was defined as the total number of cases in live births, stillbirths, and elective termination of pregnancy for fetal anomaly (ETOPFA) divided by the total number of all births in the population. RESULTS: Among the participating programs, a total of 2943 cases of EA were diagnosed with an average prevalence of 2.44 (95% confidence interval [CI], 2.352.53) per 10,000 births, ranging between 1.77 and 3.68 per 10,000 births. Of all infants diagnosed with EA, 2761 (93.8%) were live births, 82 (2.8%) stillbirths, 89 (3.0%) ETOPFA, and 11 (0.4%) had unknown outcomes. The majority of cases (2020, 68.6%), had a reported EA with fistula, 749 (25.5%) were without fistula, and 174 (5.9%) were registered with an unspecified code. CONCLUSIONS: On average, EA affected 1 in 4099 births (95% CI, 1 in 39544251 births) with prevalence varying across different geographical settings, but relatively consistent over time and comparable between surveillance programs. Findings suggest that differences in the prevalence observed among programs are likely to be attributable to variability in population ethnic compositions or issues in reporting or registration procedures of EA, rather than a real risk occurrence difference. Birth Defects Research (Part A), 2012. (c) 2012 Wiley Periodicals, Inc

    Transcriptome sequencing of three Pseudo-nitzschia species reveals comparable gene sets and the presence of Nitric Oxide Synthase genes in diatoms

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    Diatoms are among the most diverse eukaryotic microorganisms on Earth, they are responsible for a large fraction of primary production in the oceans and can be found in different habitats. Pseudo-nitzschia are marine planktonic diatoms responsible for blooms in coastal and oceanic waters. We analyzed the transcriptome of three species, Pseudo-nitzschia arenysensis, Pseudo-nitzschia delicatissima and Pseudo-nitzschia multistriata, with different levels of genetic relatedness. These species have a worldwide distribution and the last one produces the neurotoxin domoic acid. We were able to annotate about 80% of the sequences in each transcriptome and the analysis of the relative functional annotations allowed comparison of the main metabolic pathways, pathways involved in the biosynthesis of isoprenoids (MAV and MEP pathways), and pathways putatively involved in domoic acid synthesis. The search for homologous transcripts among the target species and other congeneric species resulted in the discovery of a sequence annotated as Nitric Oxide Synthase (NOS), found uniquely in Pseudo-nitzschia multistriata. The predicted protein product contained all the domains of the canonical metazoan sequence. Putative NOS sequences were found in other available diatom datasets, supporting a role for nitric oxide as signaling molecule in this group of microalgae

    Excitonic recombination dynamics in shallow quantum wells

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    We report a comprehensive study of carrier-recombination dynamics in shallow AlxGa1-xAs/GaAs quantum wells. At low crystal temperature (2 K), the excitonic radiative recombination time is shown to be strongly enhanced in shallow quantum wells with x>0.01, consistently with a model that takes into account the thermal equilibrium between the three-dimensional exciton gas of the barrier and the two-dimensional exciton gas, which are closer in energy as x decreases. Furthermore, we demonstrate the existence of a thermally activated escape mechanism due to the low effective barrier height in these structures. The nonradiative recombination is shown to dominate the carrier dynamics for temperatures as low as 10 K for x≈0.01. Our experimental observations are analyzed using three different variational exciton calculations. In particular, we study the crossover from the two-dimensional to the three-dimensional behavior of the exciton, which occurs for x as low as 0.01 and affects mainly the oscillator strength, whereas the transition energies in shallow quantum wells can be calculated, to a large extent, using the same approximations as for conventional quantum wells. The peculiar behavior of the oscillator strength at the crossover to the weak confinement regime is obtained by expansion in a large basis
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