An Introduction to Silanes and Their Clinical Applications in Dentistry

Purpose: This overview presents a description of organofunctional trialkoxysilane coupling agents (silanes), their chemistry, properties, use, and some of the main clinical experiences in dentistry. Materials and Methods: The main emphasis was on major dental journals that have been reviewed from 1958 up to the latest research news from 2002. A MEDLINE search with the key words “dental silanes” was used. Special silane literature and journals outside dentistry were also cited. Results: The main emphasis is on the use of silanes in prosthetic and restorative dentistry. Clinical relevance was based mainly on either short- or long-term tests. The interpretation of various results is not given, mainly because of controversial observations that may be very difficult to explain. Nevertheless, the majority of the clinical results pointed to silanes playing a significant role in the adhesion process. Silane reaction mechanisms were not entirely understood, and there exist several theories for bonding mechanisms for silanes and substrates. Conclusion: Dental materials offer a continuously challenging forum for silanes, and silanes will play an essential role in material developmen

Bioactive glass induced in vitro apatite formation on composite GBR membranes.

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Proliferation of osteoblast like cells on a new thermoplastic bioactive composite

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Bioactive glass as a bone substitute

The bone-bonding ability as well as the osteconductivity of a bioactive glass was studied. It was established by mechanical testing that bone bonds firmly to the glass within two months in rabbit tibia. During a 3-month implantation period in sheep it was found that cylinders were well integrated in the femur. However, empty control holes were also filled with new bone. In contrast, in the sheep mandibular jaw new bone did not fill holes which were left empty. Holes filled with granules, however, were almost completely filled with new bone. Thus, in addition to its bone-bonding ability, the studied glass also conducts bone growth along its surfaces, i.e. is osteoconductive

Proliferation of osteoblast like cells on a new thermoplastic bioactive composite

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