THE ELABORATION OF MODEL OF ACUTE PERIODONTITIS IN THE EXPERIMENT ON RATS

In connection with the search for new treatments of acute odontogenic inflammatory diseases, the elaboration of easily reproducible, accurate models of this disease in rats is actual. In the experiment on rats, the model of acute apical periodontitis followed by histopathological research was reproduced. The computer radiovisiography was held on the 5th day. The sampling of jaw with an involved tooth was carried out on the 21st day of the experiment. On the computer radioviziogramme and obtained histological blocks the pattern of acute purulent periodontitis were verified. On the 21st day of our experiment in the adjacent to the tooth bone a clear pattern of osteomyelitis was revealed. The experimental model that was investigated is easily replicable, pathologically verified. Its course is accompanied by the elaboration of complications in the form of acute odontogenic osteomyelitis