2 research outputs found
Ohtahara syndrome - early infantile epileptic encephalopathy with characteristic pattern on electroencephalograph - "suppression burst"
Rana epileptiÄka encefalopatija ili Ohtahara sindrom (OS) jedan je od najranijih oblika dobno ovisne encefalopatije, koja se javlja u prva tri mjeseca života, a obilježena je uÄestalim toniÄkim spazmima, suppression burst (S-B) zapisom u EEG-u i tvrdokornoÅ”Äu na terapiju antiepilepticima. Cilj naÅ”eg rada je opisati kliniÄku sliku, EEG osobitosti, etiologiju napadaja te karakteristiÄan prijelaz u druge oblike epileptiÄkih sindroma. Opisali smo devetero djece s Ohtahara sindromom. NajuÄestaliji uzrok bile su kortikalne razvojne anomalije mozga, a tip napadaja toniÄki spazmi. Gotovo u sve djece bio je prisutan S-B zapis u EEG-u. Pratili smo i evaluaciju u druge sindrome: Westov sindrom (WS) i Lenox-Gastautov sindrom (L-GS). Ohtahara sindrom je encefalopatija rane djeÄje dobi s karakteristiÄnom etiologijom i kliniÄkom slikom te specifiÄnim suppression-burst zapisom (S-B) u EEG-u, razliÄitim odstupanjima u neurorazvojnom ishodu te zahtijeva posebne i detaljne pretrage.Ohtahara syndrome (OS) is the earliest type of infantile epileptic encephalopathy, the age of onset is during the first three months of age. It is characterized by frequent tonic spasms, suppression- burst pattern in electroencephalograph (EEG) recording and resistance to drug treatment. The aim of this study is to evaluate clinical symptoms, EEG characteristics, etiology and transition into other epileptic syndromes. We describe 9 children with OS. The most common cause of OS were anomalies of the cortical development and the most common type of seizures tonic spasms. The EEG pattern of OS was a suppression burst (S-B) pattern in all children. Follow-up during infancy showed that OS evolved into West syndrome (WS) and Lenox Gastaut syndrome (L-GS). OS is early epileptic encephalopathy with a characteristic clinic picture, heterogeneic etiology, characteristic EEG pattern of suppression ā burst, and different neurologic outcome requiering special and detailed investigation
Ohtahara syndrome - early infantile epileptic encephalopathy with characteristic pattern on electroencephalograph - "suppression burst"
Rana epileptiÄka encefalopatija ili Ohtahara sindrom (OS) jedan je od najranijih oblika dobno ovisne encefalopatije, koja se javlja u prva tri mjeseca života, a obilježena je uÄestalim toniÄkim spazmima, suppression burst (S-B) zapisom u EEG-u i tvrdokornoÅ”Äu na terapiju antiepilepticima. Cilj naÅ”eg rada je opisati kliniÄku sliku, EEG osobitosti, etiologiju napadaja te karakteristiÄan prijelaz u druge oblike epileptiÄkih sindroma. Opisali smo devetero djece s Ohtahara sindromom. NajuÄestaliji uzrok bile su kortikalne razvojne anomalije mozga, a tip napadaja toniÄki spazmi. Gotovo u sve djece bio je prisutan S-B zapis u EEG-u. Pratili smo i evaluaciju u druge sindrome: Westov sindrom (WS) i Lenox-Gastautov sindrom (L-GS). Ohtahara sindrom je encefalopatija rane djeÄje dobi s karakteristiÄnom etiologijom i kliniÄkom slikom te specifiÄnim suppression-burst zapisom (S-B) u EEG-u, razliÄitim odstupanjima u neurorazvojnom ishodu te zahtijeva posebne i detaljne pretrage.Ohtahara syndrome (OS) is the earliest type of infantile epileptic encephalopathy, the age of onset is during the first three months of age. It is characterized by frequent tonic spasms, suppression- burst pattern in electroencephalograph (EEG) recording and resistance to drug treatment. The aim of this study is to evaluate clinical symptoms, EEG characteristics, etiology and transition into other epileptic syndromes. We describe 9 children with OS. The most common cause of OS were anomalies of the cortical development and the most common type of seizures tonic spasms. The EEG pattern of OS was a suppression burst (S-B) pattern in all children. Follow-up during infancy showed that OS evolved into West syndrome (WS) and Lenox Gastaut syndrome (L-GS). OS is early epileptic encephalopathy with a characteristic clinic picture, heterogeneic etiology, characteristic EEG pattern of suppression ā burst, and different neurologic outcome requiering special and detailed investigation