Main marketing trends in the Russian cinema market in the current realities

The article examines current marketing trends in Russian cinema and film industry, which have emerged in the 21st century in Russian cinema and international federation of film societies. The aim of the study is to define the directions of marketing strategies for enlarging the target audience and extracting the maximum possible profit from cinematographic business. Based on key works on marketing and their own observations, the authors investigated the concept and essence of marketing, its content and specifics. Various ways of increasing the audience of cinemas and customer loyalty programmes were analysed. The main societal trends, which influence the creation of cinematographic images in contemporary cinematography, were identified, and the factors of modern society development and their correlation with the world of cinematography, including the degree of their influence, were pointed out. The results of the study can serve as a basis for evaluating the effectiveness of marketing strategies

Морфофенотипический предиктор развития висцерального ожирения у больных шизофренией, получающих антипсихотическую терапию

Objective: revealing the role of morphophenotypic indices in the development of visceral obesity in patients with schizophrenia receiving quetiapine and risperidone therapy.Materials and methods. 56 indoor patients with schizophrenia who received quetiapine (n = 23) or risperidone (n = 33) at medium doses were examined. Included persons were from 18 to 65 years old with at least a 1 year history of disease, the condition of which met the criteria of schizophrenia according to ICD-10. The Basis map of sociodemographic and clinical-dynamic signs for patients with schizophrenia was filled in, PANSS in the adapted Russian version – SCI-PANSS, noninvasive bioimpedancemetry, measurement of growth, transversethoracic, biacromial and bicrystal diameter, with calculation of body mass indexes, Tanner and Rees – Eysenk and definition of integral morphophenotypic indicators were carried out. Statistical processing was performed using Student’s t-test with a preliminary estimate of Pearson’s χ2 normal distribution, the Mann – Whitney U test to compare independent samples, the Spearman correlation analysis, the two-sided Fisher test.Results. There were no significant differences in both subgroups in terms of bioimpedancemetry. The correlation between the level of visceral fat and the Rees – Eysenk index in patients receiving risperidone was a moderate inverse: the greater the value of the Rees – Eysenk index, the lower the level of visceral fat (r = –0.73381, t = –4.70833, p = 0.00015). The correlation between the Tanner index and the level of visceral fat in the quetiapine subgroup was strong: the larger the Tanner index, the higher the visceral fat level (r = 0.7763, t = 4.08481, p = 0.00181); in the risperidone subgroup, there was an average direct correlation (r = 0.48133, t = 2.39356, p = 0.02716).Conclusion. The magnitude of the Rees – Eysenk index of schizophrenic patients can be considered among other factors in the management of risperidone in individuals with asthenic physique. The determination of the Tanner index at the beginning of treatment can play the role of a prognostic factor in the development of visceral obesity in patients with schizophrenia in the planned use as a basic therapy for quetiapine.Цель – выявление роли морфофенотипических показателей в развитии висцерального ожирения у больных шизофренией, получающих терапию кветиапином и рисперидоном.Материалы и методы. Обследованы 56 стационарных пациентов с шизофренией, принимавших кветиапин (n = 23) или рисперидон (n = 33) в средних дозах. Включались лица 18–65 лет с давностью катамнеза заболевания не менее 1 года, состояние которых соответствовало критериям шизофрении по МКБ-10. Применялись Базисная карта социо-демографических и клинико-динамических признаков для больных шизофренией, PANSS в адаптированной русской версии – SCI-PANSS. Проводились неинвазивная биоимпедансометрия, измерение роста, поперечно-грудного, биакромиального и бикристального диаметра, вычисление индексов массы тела, Tanner и Rees – Eysenk и определялись интегральные морфофенотипические показатели. Статистическую обработку проводили с использованием t-критерия Стьюдента с предварительной оценкой нормального распределения, χ2 Пирсона, U-критерия Манна – Уитни для сравнения независимых выборок, корреляционного анализа Спирмена (r), двустороннего критерия Фишера.Результаты. Не выявлено достоверных различий в обеих подгруппах по показателям биоимпедансометрии. Корреляция между уровнем висцерального жира и индексом Rees –Eysenk у пациентов, получавших рисперидон, была умеренной обратной: чем больше величина индекса Rees – Eysenk, тем ниже уровень висцерального жира (r = –0,73381; t = –4,70833; p = 0,00015). Корреляция между величиной индекса Tanner и уровнем висцерального жира в группе кветиапина была сильной прямой: чем больше индекс Tanner, тем выше уровень висцерального жира (r = 0,77633; t = 4,08481; p = 0,00181); в группе рисперидона наблюдалась средняя прямая корреляция (r = 0,48133; t = 2,39356; p = 0,02716).Заключение. Величина индекса Rees – Eysenk больных шизофренией может рассматриваться среди других факторов при решении применения рисперидона у лиц с астеническим телосложением. Определение показателей индекса Tanner в начале лечения может играть роль прогностического фактора развития висцерального ожирения у больных шизофренией при планируемом использовании в качестве базисной терапии кветиапина

Половые различия в клинических особенностях антипсихотикиндуцированной гиперпролактинемии у больных шизофренией

The goal was to identify gender differences in the clinical features of antipsychotic-induced hyperprolactinemia in patients with schizophrenia.Materials and methods. 98 patients from the Department of Endogenous Disorders of the Research Institute of Mental Health Clinic in Tomsk were examined. Persons aged 18–50 were included with followup treatment for at least 1 year, whose condition corresponded to the ICD-10 schizophrenia criteria. Prolactin levels were determined by ELISA using the PRL Test System reagent kit (MonobindInc., USA). The base map of sociodemographic and clinical-dynamic features for patients with schizophrenia was used. Statistical processing of data was performed using the Statistica 12.0 software package. Mann–Whitney U test, Pearson’s χ² criterion, including Yates correction, and Fisher’s two-sided test were used for comparing small samples.Results. The average serum concentration of prolactin in women was 52.4 ± 39.1 ng/ml, in men it was 26.7 ± 19.7 ng/ml. Hyperprolactinemia was detected in 23 (47.9%) women and 25 (50%) men. Among women with hyperprolactinemia, statistically significant “Weight Gain” and “Headache” parameters were more common (p = 0.044 and p = 0.005, respectively). Men with hyperprolactinemia had higher BMI rates (p = 0.0066). For the rest of the UKU paragraphs, no significant differences were found in both men and women. Men presented fewer complaints and were less willing to discuss sexual dysfunction.Conclusion. Antipsychotic-induced hyperprolactinemia in patients with schizophrenia does not always have a full range of specific clinical manifestations and needs careful examination of patients with account of gender characteristics, as well as regular monitoring of the prolactin level in the serum of patients. Цель – выявление половых различий в клинических особенностях антипсихотик-индуцированной гиперпролактинемии у больных шизофренией.Материалы и методы. Обследованы 98 больных из отделения эндогенных расстройств клиники НИИ психического здоровья г. Томска. Включались лица 18–50 лет с давностью катамнеза заболевания не менее 1 года, состояние которых соответствовало критериям шизофрении по МКБ-10. Определение пролактина проводили иммуноферментным методом с использованием набора реагентов PRL Test System (Monobind Inc., США). Применялись Базисная карта социодемографических и клиникодинамических признаков для больных шизофренией, шкала UKU в адаптированной русской версии. Статистическую обработку проводили с использованием пакета программ Statistica 12.0. Применяли непараметрический U-критерий Манна – Уитни, χ² Пирсона, в том числе с учетом поправки Йейтса, для сравнения малых выборок был использован двухсторонний критерий Фишера.Результаты. Средние показатели концентрации пролактина в сыворотке крови у женщин зафиксированы на уровне (52,4 ± 39,1) нг/мл, у мужчин – (26,7 ± 19,7) нг/мл. Гиперпролактинемия была выявлена у 23 (47,9%) женщин и 25 (50%) мужчин. У женщин с гиперпролактинемией статистически значимо чаще встречались показатели «прибавка в весе» и «головная боль» (р = 0,044 и р = 0,005 соответственно), у мужчин с гиперпролактинемией – более высокие показатели индекса массы тела (p = 0,0066). По остальным пунктам UKU значимых различий не выявлено как у мужчин, так и у женщин. Мужчины предъявляли меньшее количество жалоб и были менее доступны для обсуждения сексуальной дисфункции.Заключение. Антипсихотик-индуцированная гиперпролактинемия у больных шизофренией не всегда проявляется полным спектром специфических клинических симптомов и нуждается в тщательном обследовании пациентов с учетом пола, а также в регулярном мониторинге уровня пролактина в сыворотке крови больных.

Tuberculosis Incidence in Prisons: A Systematic Review

A systematic review by Iacopo Baussano and colleagues synthesizes published research to show that improved tuberculosis (TB) control in prisons could significantly reduce the burden of TB both inside and outside prisons

Ethics of the application of artificial intelligence in human resource management

The article reveals the main ethical problems and contradictions associated with the use of artificial intelligence. The paper reveals the concept of “artificial intelligence”. The authors analyse two areas of ethical problems of artificial intelligence: fundamental ideas about the ethics of artificial intelligent systems and the creation of ethical norms.The paper investigates the work of world organizations on the development of ethical standards for the use of artificial intelligence: the Institute of Electrical and Electronics Engineers and UNESCO. The study analyses the main difficulties in the implementation of artificial intelligent systems: the attitude of employees to the use of robots in production activities and the automation of processes that affect their work functions and work organization; ethical issues related to retraining and re-certification of employees in connection with the introduction of new software products and robots; ethical issues in reducing staff as a result of the introduction of artificial intelligence and automation of production and business processes; ethical problems of the processing of personal data of employees, including assessments of their psychological and physical condition, personal qualities and character traits, values  and beliefs by specialized programs based on artificial intelligence, as well as tracking the work of employees; ethical contradictions when using special devices and tracking technologies in robotic technology and modern software products, which also extend to the employees interacting with them

The research of moisture forms in the baking yeast by the thermogravimetric analysis method

The thermogravimetry method is one of the few absolute methods of analysis, that makes it one of the most accurate methods. In this research, thermogravimetric analysis of baking yeast (Saccharomyces cerevisiae) was carried out. It allowed to identify temperature zones, which correspond to dripping with various link energy, as well as to predict operating parameters of the process of dehumidification and to choose their most effective dehydration method. The studies were conducted in the laboratory of the collective use center "Control and management of energy efficient projects" of the "Voronezh state university of engineering technologies" on the simultaneous thermal analysis device STA 449 F3 model (NETZSCH, Germany). The device records the change in a substance mass and the difference of the heat flow inside the crucible containing the sample and the crucible containing the standard analyte. The analyzer's working principle is based on continuous recording of the dependence of the material mass on time or temperature and its being heated to the selected temperature program in a specified gas atmosphere. The release or absorption of heat by the sample due to phase transitions or chemical reactions is recorded simultaneously. The study was performed in the following modes: the pressure is atmospheric, the maximum temperature is 588 K, the rate of temperature change is 5 K/min. The experiments were performed in aluminum crucibles with a total weight of 12 mg. The software NETZSCH Proteus was used for processing of the obtained TG and DTG curves. The analysis of the obtained data allowed to identify periods of water dehydration and solids transformation by thermal effect on baking yeast, and to identify temperature zones, which correspond to the release of moisture with different link form and energy

Sexual differences in the clinical features of antipsychotic-induced hyperprolactinemia in patients with schizophrenia

The goal was to identify gender differences in the clinical features of antipsychotic-induced hyperprolactinemia in patients with schizophrenia.Materials and methods. 98 patients from the Department of Endogenous Disorders of the Research Institute of Mental Health Clinic in Tomsk were examined. Persons aged 18–50 were included with followup treatment for at least 1 year, whose condition corresponded to the ICD-10 schizophrenia criteria. Prolactin levels were determined by ELISA using the PRL Test System reagent kit (MonobindInc., USA). The base map of sociodemographic and clinical-dynamic features for patients with schizophrenia was used. Statistical processing of data was performed using the Statistica 12.0 software package. Mann–Whitney U test, Pearson’s χ² criterion, including Yates correction, and Fisher’s two-sided test were used for comparing small samples.Results. The average serum concentration of prolactin in women was 52.4 ± 39.1 ng/ml, in men it was 26.7 ± 19.7 ng/ml. Hyperprolactinemia was detected in 23 (47.9%) women and 25 (50%) men. Among women with hyperprolactinemia, statistically significant “Weight Gain” and “Headache” parameters were more common (p = 0.044 and p = 0.005, respectively). Men with hyperprolactinemia had higher BMI rates (p = 0.0066). For the rest of the UKU paragraphs, no significant differences were found in both men and women. Men presented fewer complaints and were less willing to discuss sexual dysfunction.Conclusion. Antipsychotic-induced hyperprolactinemia in patients with schizophrenia does not always have a full range of specific clinical manifestations and needs careful examination of patients with account of gender characteristics, as well as regular monitoring of the prolactin level in the serum of patients