Percutaneous nephrolithotripsy: the algorithm of actions in identifying bleeding from renal vessels

Bleeding, developing as a result of damage to the renal vessels, is a serious complication of surgical treatment of kidney stones. The ineffectiveness of conservative therapy is an indicator of superselective vascular embolization kidneys. The use of the technique demonstrates high efficiency of elimination of bleeding the patient in the postoperative period after NLP.Кровотечение, развивающееся в результате повреждения почечных сосудов при перкутанной нефролитотрипсии, является серьезным осложнением оперативного лечения мочекаменной болезни. Неэффективность гемостатической терапии является показанием для проведения суперселективной змболизации почечных сосудов. Использование данной методики демонстрирует высокую эффективность устранения кровотечения в послеоперационном периоде у пациентов с данным осложнением

Application superselective embolization of renal vessels with bleeding after PNL in patients with urolithiasis

Bleeding, developing as a result of damage to the renal vessels, is a serious complication of surgical treatment of kidney stones. The ineffectiveness of conservative therapy is an indicator of superselective vascular embolization kidneys. The use of the technique demonstrates high efficiency of elimination of bleeding the patient in the postoperative period after NLP.Кровотечение, развивающееся в результате повреждения почечных сосудов при перкутанной нефролитотрипсии, является серьезным осложнением оперативного лечения мочекаменной болезни. Неэффективность гемостатической терапии является показанием для проведения суперселективной эмболизации почечных сосудов. Использование данной методики демонстрирует высокую эффективность устранения кровотечения в послеоперационном периоде у пациентов с данным осложнением

Pinolide, a New Nonenolide Produced by Didymella pinodes, the Causal Agent of Ascochyta Blight on Pisum sativum

An aggressive isolate of Didymella pinodes isolated from pea (Pisum sativum) produced four different metabolites in vitro. The metabolites isolated from the culture filtrates were characterized by spectroscopic and optical methods. A new nonenolide, named pinolide, was isolated and characterized as (2S*,7R*,8S*,5E,9R*)-2,7,8-trihydroxy-9-propy1-5-nonen-9-olide. Pinolidoxin, the main toxin produced by D. pinodes, was also isolated together with two other closely related nonenolides, identified as herbarumin II and 2-epi-herbarumin II. Herbarumin II and 2-epi-herbarumin II have been previously isolated from the fungi Phoma herbarum and Paraphaeosphaeria recurvifoliae, respectively, but described here to be isolated for the first time from D. pinodes. When tested on leaves of the host plant and other legumes and weeds, pinolidoxin was phytotoxic in all of the plant species, whereas the other three nonenolides did not produce any symptoms. The importance of the stereochemistry of the hydroxy group at C-7 on phytotoxicity also is discussed