105 research outputs found
More on Massive 3D Supergravity
Completing earlier work on three dimensional (3D) N=1 supergravity with
curvature-squared terms, we construct the general supergravity extension of
cosmological massive gravity theories. We expand about supersymmetric anti-de
Sitter vacua, finding the conditions for bulk unitarity and the critical points
in parameter space at which the spectrum changes. We discuss implications for
the dual conformal field theory.Comment: v1 : 53 pages, 1 figure; v2 : significantly shortened, 42 p., version
published in Class. Quant. Gra
Holographic two-point functions for 4d log-gravity
We compute holographic one- and two-point functions of critical
higher-curvature gravity in four dimensions. The two most important operators
are the stress tensor and its logarithmic partner, sourced by ordinary massless
and by logarithmic non-normalisable gravitons, respectively. In addition, the
logarithmic gravitons source two ordinary operators, one with spin-one and one
with spin-zero. The one-point function of the stress tensor vanishes for all
Einstein solutions, but has a non-zero contribution from logarithmic gravitons.
The two-point functions of all operators match the expectations from a
three-dimensional logarithmic conformal field theory.Comment: 35 pages; v2: typos corrected, added reference; v3: shorter
introduction, minor changes in the text in section 3, added reference;
published versio
Correlated conformation and charge transport in multiwall carbon nanotube - conducting polymer nanocomposites
The strikingly different charge transport behaviors in nanocomposites of
multiwall carbon nanotubes (MWNTs) and conducting polymer polyethylene
dioxythiophene - polystyrene sulfonic acid (PEDOT-PSS) at low temperatures are
explained by probing their conformational properties using small angle X-ray
scattering (SAXS). The SAXS studies indicate assembly of elongated PEDOT-PSS
globules on the walls of nanotubes, coating them partially thereby limiting the
interaction between the nanotubes in the polymer matrix. This results in a
charge transport governed mainly by small polarons in the conducting polymer
despite the presence of metallic MWNTs. At T > 4 K, hopping of the charge
carriers following 1D-VRH is evident which also gives rise to a positive
magnetoresistance (MR) with an enhanced localization length (~ 5 nm) due to the
presence of MWNTs. However, at T < 4 K, the observation of an unconventional
positive temperature coefficient of resistivity (TCR) is attributed to small
polaron tunnelling. The exceptionally large negative MR observed in this
temperature regime is conjectured to be due to the presence of quasi-1D MWNTs
that can aid in lowering the tunnelling barrier across the nanotube - polymer
boundary resulting in large delocalization.Comment: Accepted J. Phys.: Condens. Matte
Long non-coding RNAs modulate tumor microenvironment to promote metastasis: novel avenue for therapeutic intervention
Cancer is a devastating disease and the primary cause of morbidity and mortality worldwide, with cancer metastasis responsible for 90% of cancer-related deaths. Cancer metastasis is a multistep process characterized by spreading of cancer cells from the primary tumor and acquiring molecular and phenotypic changes that enable them to expand and colonize in distant organs. Despite recent advancements, the underlying molecular mechanism(s) of cancer metastasis is limited and requires further exploration. In addition to genetic alterations, epigenetic changes have been demonstrated to play an important role in the development of cancer metastasis. Long non-coding RNAs (lncRNAs) are considered one of the most critical epigenetic regulators. By regulating signaling pathways and acting as decoys, guides, and scaffolds, they modulate key molecules in every step of cancer metastasis such as dissemination of carcinoma cells, intravascular transit, and metastatic colonization. Gaining a good knowledge of the detailed molecular basis underlying lncRNAs regulating cancer metastasis may provide previously unknown therapeutic and diagnostic lncRNAs for patients with metastatic disease. In this review, we concentrate on the molecular mechanisms underlying lncRNAs in the regulation of cancer metastasis, the cross-talk with metabolic reprogramming, modulating cancer cell anoikis resistance, influencing metastatic microenvironment, and the interaction with pre-metastatic niche formation. In addition, we also discuss the clinical utility and therapeutic potential of lncRNAs for cancer treatment. Finally, we also represent areas for future research in this rapidly developing field
Treating implicit trauma: a quasi-experimental study comparing the EMDR Therapy Standard Protocol with a ‘Blind 2 Therapist’ version within a trauma capacity building project in Northern Iraq
Psychological trauma is a silent epidemic which presents as a global public health issue, often in the form of post- traumatic stress disorder (PTSD). Eye Movement Desensitisation and Reprocessing (EMDR) Therapy is an empirically supported treatment intervention for PTSD and has been used as part of trauma-capacity building, particularly in low- and middle-income countries (LMIC). For some survivor’s, their trauma experiences cannot be spoken of: they may be alluded to, suggested and though not directly expressed. There are several factors as to why these implicit trauma experiences are ‘unspoken’, for example, when the trauma involves a deep-rooted sense of shame or guilt, a distorted sense of over-responsibility or when to speak of the trauma engenders fear of retribution, reprisal and consequence. This paper will explore the effectiveness of using two protocol variations of EMDR Therapy—standard versus a ‘Blind 2 Therapist’ protocol version as part of a quasi-experimental study which took place in Northern Iraq. The study contains two projects and subsequently tested several hypotheses regarding safety, effectiveness, efficiency and relevance of the ‘Blind 2 Therapist’ protocol within EMDR Therapy. Results indicated support for the B2T protocol intervention with various trauma populations including Yezidi survivors of Islamic State of Iraq and the Levant (ISIL)—also known as Daesh
Physicochemical Characteristics and Droplet Impact Dynamics of Superhydrophobic Carbon Nanotube Arrays
Interaction between prenatal pesticide exposure and a common polymorphism in the PON1 gene on DNA methylation in genes associated with cardio-metabolic disease risk—an exploratory study
- …