773 research outputs found

    Two-step contribution to the spin-longitudinal and spin-transverse cross sections of the quasielastic (p,n) reactions

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    The two-step contribution to the spin-longitudinal and the spin-transverse cross sections of ^{12}C,^{40}Ca(p,n) reactions at 494 MeV and 346 MeV is calculated. We use a plane-wave approximation and evaluate the relative contributions from the one-step and the two-step processes. We found that the ratios of the two-step to the one-step processes are larger in the spin-transverse cross sections than in the spin-longitudinal ones. Combining these results with the distorted-wave impulse approximation (DWIA) results we obtained considerable two-step contributions to the spin-longitudinal and the spin-transverse cross sections. The two-step processes are important in accounting for the underestimation of the DWIA results for the spin-longitudinal and the spin-transverse cross sections.Comment: LaTeX 11 pages, 10 figure

    The Rules of Human T Cell Fate in vivo.

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    The processes governing lymphocyte fate (division, differentiation, and death), are typically assumed to be independent of cell age. This assumption has been challenged by a series of elegant studies which clearly show that, for murine cells in vitro, lymphocyte fate is age-dependent and that younger cells (i.e., cells which have recently divided) are less likely to divide or die. Here we investigate whether the same rules determine human T cell fate in vivo. We combined data from in vivo stable isotope labeling in healthy humans with stochastic, agent-based mathematical modeling. We show firstly that the choice of model paradigm has a large impact on parameter estimates obtained using stable isotope labeling i.e., different models fitted to the same data can yield very different estimates of T cell lifespan. Secondly, we found no evidence in humans in vivo to support the model in which younger T cells are less likely to divide or die. This age-dependent model never provided the best description of isotope labeling; this was true for naïve and memory, CD4+ and CD8+ T cells. Furthermore, this age-dependent model also failed to predict an independent data set in which the link between division and death was explored using Annexin V and deuterated glucose. In contrast, the age-independent model provided the best description of both naïve and memory T cell dynamics and was also able to predict the independent dataset

    Magnetooptic properties of self-trapped excitons in cesium halides

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    A model for the electronic structure of self-trapped excitons in Cs halides is proposed. By applying it, reasonable interpretations were obtained for the magnetic circular polarization (MCP) of the 2 intrinsic emissions in CsI, and for the MCP and EPR in CsBr

    Selective breeding and selection mapping using a novel wild-derived heterogeneous stock of mice revealed two closely-linked loci for tameness

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    Tameness is a major behavioral factor for domestication, and can be divided into two potential components: motivation to approach humans (active tameness) and reluctance to avoid humans (passive tameness). We identified genetic loci for active tameness through selective breeding, selection mapping, and association analysis. In previous work using laboratory and wild mouse strains, we found that laboratory strains were predominantly selected for passive tameness but not active tameness during their domestication. To identify genetic regions associated with active tameness, we applied selective breeding over 9 generations for contacting, a behavioural parameter strongly associated with active tameness. The prerequisite for successful selective breeding is high genetic variation in the target population, so we established and used a novel resource, wild-derived heterogeneous stock (WHS) mice from eight wild strains. The mice had genetic variations not present in other outbred mouse populations. Selective breeding of the WHS mice increased the contacting level through the generations. Selection mapping was applied to the selected population using a simulation based on a non-selection model and inferred haplotype data derived from single-nucleotide polymorphisms. We found a genomic signature for selection on chromosome 11 containing two closely linked loci

    Stability Assessment of Regenerated Hierarchical ZSM-48 Zeolite Designed by Post-Synthesis Treatment for Catalytic Cracking of Light Naphtha

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    Hierarchical ZSM-48, a one-dimensional pore system zeolite with the presence of mesopores, was obtained by post-synthesis alkaline and acid treatments. Hierarchical ZSM-48 exhibited excellent hexane cracking activity compared to parent ZSM-48, which can be attributed to better diffusion as a result of the created mesoporosity. Moreover, the post-synthesis treatment allowed for manipulation of the distribution of active sites. Consequently, better stability and higher propylene selectivity were accomplished. The spent catalyst was regenerated by removing the deposited coke from the pores, and the regenerated catalyst was characterized again to investigate the recyclability of the hierarchical structure achieved. Parent ZSM-48 showed the same textural and acidic properties after regeneration, while the structure of the post-treated sample suffered from serious defects. The defects severely decreased the number of active sites as measured by pyridine Fourier transform infrared spectroscopy and caused major structural collapse as observed by scanning electron microscopy and transmission electron microscopy

    Torsion pairs and rigid objects in tubes

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    We classify the torsion pairs in a tube category and show that they are in bijection with maximal rigid objects in the extension of the tube category containing the Pruefer and adic modules. We show that the annulus geometric model for the tube category can be extended to the larger category and interpret torsion pairs, maximal rigid objects and the bijection between them geometrically. We also give a similar geometric description in the case of the linear orientation of a Dynkin quiver of type A.Comment: 25 pages, 13 figures. Paper shortened. Minor errors correcte

    Data-based estimates of the ocean carbon sink variability – First results of the Surface Ocean pCO2 Mapping intercomparison (SOCOM)

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    Using measurements of the surface-ocean CO2 partial pressure (pCO2) and 14 different pCO2 mapping methods recently collated by the Surface Ocean pCO2 Mapping intercomparison (SOCOM) initiative, variations in regional and global sea–air CO2 fluxes are investigated. Though the available mapping methods use widely different approaches, we find relatively consistent estimates of regional pCO2 seasonality, in line with previous estimates. In terms of interannual variability (IAV), all mapping methods estimate the largest variations to occur in the eastern equatorial Pacific. Despite considerable spread in the detailed variations, mapping methods that fit the data more closely also tend to agree more closely with each other in regional averages. Encouragingly, this includes mapping methods belonging to complementary types – taking variability either directly from the pCO2 data or indirectly from driver data via regression. From a weighted ensemble average, we find an IAV amplitude of the global sea–air CO2 flux of 0.31 PgC yr−1 (standard deviation over 1992–2009), which is larger than simulated by biogeochemical process models. From a decadal perspective, the global ocean CO2 uptake is estimated to have gradually increased since about 2000, with little decadal change prior to that. The weighted mean net global ocean CO2 sink estimated by the SOCOM ensemble is −1.75 PgC yr−1 (1992–2009), consistent within uncertainties with estimates from ocean-interior carbon data or atmospheric oxygen trend

    How do microbiota associated with an invasive seaweed vary across scales?

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    Communities are shaped by scale dependent processes. To study the diversity and variation of microbial communities across scales, the invasive and widespread seaweed Agarophyton vermiculophyllum presents a unique opportunity. We characterized pro‐ and eukaryotic communities associated with this holobiont across its known distribution range, which stretches over the northern hemisphere. Our data reveal that community composition and diversity in the holobiont vary at local but also larger geographic scales. While processes acting at the local scale (i.e., within population) are the main structuring drivers of associated microbial communities, changes in community composition also depend on processes acting at larger geographic scales. Interestingly, the largest analysed scale (i.e., native and non‐native ranges) explained variation in the prevalence of predicted functional groups, which could suggest a functional shift in microbiota occurred over the course of the invasion process. While high variability in microbiota at the local scale supports A. vermiculophyllum to be a generalist host, we also identified a number of core taxa. These geographically independent holobiont members imply that cointroduction of specific microbiota may have additionally promoted the invasion process

    Multiband optical variability of the blazar OJ 287 during its outbursts in 2015 -- 2016

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    We present recent optical photometric observations of the blazar OJ 287 taken during September 2015 -- May 2016. Our intense observations of the blazar started in November 2015 and continued until May 2016 and included detection of the large optical outburst in December 2016 that was predicted using the binary black hole model for OJ 287. For our observing campaign, we used a total of 9 ground based optical telescopes of which one is in Japan, one is in India, three are in Bulgaria, one is in Serbia, one is in Georgia, and two are in the USA. These observations were carried out in 102 nights with a total of ~ 1000 image frames in BVRI bands, though the majority were in the R band. We detected a second comparably strong flare in March 2016. In addition, we investigated multi-band flux variations, colour variations, and spectral changes in the blazar on diverse timescales as they are useful in understanding the emission mechanisms. We briefly discuss the possible physical mechanisms most likely responsible for the observed flux, colour and spectral variability.Comment: 11 pages, 6 figures, 4 tables; Accepted for publication in MNRA
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