The Nature of High Soil Radioactivity in Chinese Province Guangdong

Soil is a basic component of biosphere and its important natural resource. The article deals with the analysis of soil radioactivity in Chinese province Guangdong. In the course of the analysis, it was stated that highly radioactive soil of China had been formed due to deep chemical weathering of highly radioactive potassium granites. High uranium and thorium contents in them are caused by specific conditions of weathering crust formation and subsequent pedogenesis. High dose loads for a man are formed in the development fields of such rock types

The Nature of High Soil Radioactivity in Chinese Province Guangdong

Soil is a basic component of biosphere and its important natural resource. The article deals with the analysis of soil radioactivity in Chinese province Guangdong. In the course of the analysis, it was stated that highly radioactive soil of China had been formed due to deep chemical weathering of highly radioactive potassium granites. High uranium and thorium contents in them are caused by specific conditions of weathering crust formation and subsequent pedogenesis. High dose loads for a man are formed in the development fields of such rock types

Evaluation of Psychophysiological and Hormonal Changes in Acute and Chronic Forms of Central Serous Chorioretinopathy

Aim: to evaluate changes in the parameters of the visual system, psycho-physiological reactions (psychoemotional changes), and hormonal changes in patients with central serous chorioretinopathy and on this basis to develop a conceptual scheme for the activation of pathogenetic mechanisms of the formation of acute and chronic forms of the disease. Material and methods. 40 people with central serous chorioretinopathy and 26 control subjects were examined with the assessment of psychophysiological (psychoemotional) and hormonal changes.Results. The most informative criteria have been identified which determine various forms of the clinical course of central serous chorioretinopathy: the area of damage to the retinal pigment epithelium, psycho-emotional changes (the difficulties of role-playing, dependence on other people in domestic and professional environment, a high degree of reactive and personal anxiety, paranoia and level of distress), violation of the psycho-physiological characteristics of the state of the visual system, changes in hormonal regulation (cortisol, thyroid hormones, dehydroepiandrosterone, melatonin, 17-OH-progesterone, testosterone).Conclusion. The complex of psychophysiological changes that form the basis for the pathogenesis of central serous chorioretinopathy, according to the feedback mechanism, enhances the initial moments of the disease, exacerbates the severity of clinical manifestations and leads to chronicity of the pathological process, causing, thus, the complexity of diagnosis and treatment of central serous chorioretinopathy

Kaposi's sarcoma associated with Wegener’s granulomatosi

A case of Kaposi's sarcoma development in a pt with Wegener's granulomatosis during immunosupres- sive treatment with cyclophosphane and prednisolone

The effects of prolonged oral administration of gold nanoparticles on the morphology of hematopoietic and lymphoid organs

Currently, the usage of gold nanoparticles as photosensitizers and immunomodulators for plasmonic photothermal therapy has attracted a great attention of researches and end-users. In our work, the influence of prolonged peroral administration of gold nanoparticles (GNPs) with different sizes on the morphological changes of hematopoietic and lymphoid organs was investigated. The 24 white outbred male rats weighing 180-220 g were randomly divided into groups and administered orally for 30 days the suspension of gold nanospheres with diameters of 2, 15 and 50 nm at a dosage of 190 μg/kg of animal body weight. To prevent GNPs aggregation in a tissue and enhance biocompatibility, they were functionalized with thiolated polyethylene glycol. The withdrawal of the animals from the experiment and sampling of spleen, lymph nodes and bone marrow tissues for morphological study were performed a day after the last administration. In the spleen the boundary between the red and white pulp was not clearly differ in all experimental groups, lymphoid follicles were significantly increased in size, containing bright germinative centers represented by large blast cells. The stimulation of lymphocyte and myelocytic series of hematopoiesis was recorded at morphological study of the bone marrow. The number of immunoblasts and large lymphocytes was increased in all structural zones of lymph nodes. The more pronounced changes were found in the group with administration of 15 nm nanoparticles. Thus, the morphological changes of cellular components of hematopoietic organs have size-dependent character and indicate the activation of the migration, proliferation and differentiation of immune cells after prolonged oral administration of GNPs

Grain quality indicators and size-dependent fractional composition in winter rye cultivars under the conditions of the Lower Volga region

Background. Grain quality indicators of winter rye cultivars were analyzed in connection with the size-dependent fractional composition of their grain in the Lower Volga environments.Materials and methods. The research material included 22 cultivars developed at various Russian scientific institutions, 3 Belarusian ones, and 3 cultivars bred at the Federal Center of Agriculture Research of the South-East Region. Comparative trials were conducted in 2021–2022 on 13.2 m2 plots in two field replications. The following grain quality indicators were studied: grain test weight, 1000 grain weight, size-dependent fractional composition, Hagberg falling number, amylogram peak height, starch gelatinization temperature, protein content, and rheological properties of the meal/water slurry.Results. Protein content was recorded at a level of 9.98–10.85%, while the starch gelatinization temperature was high due to the June air temperatures higher than the norm. Significant differences among the cultivars were found in the fractional composition of grain: 12 forms were identified with medium viscosity of the meal/water slurry and the fine-grain fraction content up to 30% of the total weight.Conclusions. There is a positive significant correlation between the five studied indicators characterizing the rheological properties of the meal/water slurry made from the grain of winter rye cultivars and the grain fraction composition (0.82*–0.91*)

Анатомо-топографические критерии эффективности непроникающей глубокой склерэктомии

PURPOSE: To assess the anatomical and topographic features of the trabeculo-descemet membrane when forming the outflow pathways of the intraocular fluid after nonpenetrating deep sclerectomy, and also to substantiate the indications and timing of laser descemetopuncture. METHODS: The effectiveness of antihypertensive laser goniopuncture was analyzed in 500 patients with primary open-angle glaucoma. Group 1 consisted of 250 patients (retrospective study), group 2 included 250 patients (prospective study). Clinical groups were comparable by gender, age, glaucoma stage and hypotensive therapy regimen. The follow-up period lasted for 3 years. All patients postoperatively underwent ultrasound biomicroscopy of internal fistula, intrascleral channel and filtering blebs by means of UBM-Hi (Opticon, Italy). The principal difference of the second clinical group was strict adherence to the technology of surgical stage of the operation (the height of the wave function was at least 0.8±0.09 mm), and to laser goniopuncture terms and technology. RESULTS: We determined optimal UBM-criteria of internal fistula: height — 0.8±0.09 mm, thickness — 0.09±0.004 mm. Performing laser goniopuncture 1-1.12 months after the surgery was justified in 100% of cases. In group 1 laser goniopuncture was conducted 3.4±1.9 months after the surgery. Intraocular fluid outflow pathways were functional in 59.6% 1 year after laser goniopuncture as compared to 24.8% after 3 years. In 2 group laser goniopuncture was conducted in 1.12±0.08 months. Absolute surgical success after 12 months amounted to 84.8%, and 60.4%after 3 years of follow-up. CONCLUSION: Regarding penetrating deep sclerectomy as a two-step procedure in all cases, strict implementation of the technology and time intervals between surgical and laser stages allows optimizing the morphogenesis of outflow pathways and increasing the hypotensive effect of the combined intervention. ЦЕЛЬ. Оценить анатомо-топографические особенности трабекуло-десцеметовой мембраны при формировании путей оттока внутриглазной жидкости после непроникающей глубокой склерэктомии (НГСЭ), а также обосновать показания и сроки проведения лазерной десцеметогониопунктуры (ЛДГП). МЕТОДЫ. Проанализирована гипотензивная эффективность НГСЭ у 500 пациентов с первичной открытоугольной глаукомой. 1-я группа включала 250 пациентов (ретроспективное исследование), 2-я группа — 250 пациентов (проспективное исследование). Клинические группы релевантны по полу, возрасту, стадиям глаукомы и режиму местной терапии. Сроки наблюдения — 3 года. Всем пациентам в послеоперационном периоде проводилась ультразвуковая биомикроскопия (УБМ) внутренней фистулы, интрасклерального канала и фильтрационной подушки с оценкой параметрических (высота) и морфометрических (степень эхогенности) показателей. Принципиальным отличием 2-й клинической группы явилось соблюдение технологии хирургического этапа операции (высота ВФ не менее 0,8±0,09 мм), а также сроков и технологии проведения ЛДГП. РЕЗУЛЬТАТЫ. Определены оптимальные УБМ-критерии внутренней фистулы после НГСЭ: высота 0,8±0,09 мм, толщина 0,09±0,004 мм и наличие в ней участка «прерывания» после ЛДГП. Обосновано выполнение ЛДГП в 100% случаев в сроки 1-1,12 месяца после хирургического этапа. В 1-й группе сроки ЛДГП составили 3,4±1,9 месяца, а состоятельные пути оттока ВГЖ определялись в 59,6% через 1 год, в 24,8% через 3 года после НГСЭ. Во 2-й группе сроки ЛДГП составили 1,12±0,08 месяца. Через 12 месяцев полный гипотензивный успех определялся в 84,8%, к 3 годам — в 60,4% случаев. ЗАКЛЮЧЕНИЕ. Позиционирование НГСЭ как двухэтапной процедуры в абсолютном количестве случаев, строгое соблюдение технологии и временного интервала между хирургическим и лазерным этапами позволяют оптимизировать морфогенез путей оттока и повысить полный гипотензивный эффект этих вмешательств.