Significance of intaoperative duplex ultrasonography at the endovascular interventions on the lower limb arteries

The article presents the results of intraoperative duplex ultrasonography (DUS) at the endovascular interventions (EV) in patients with occlusive-stenotic injuries of lower limb arteries. 48 segments of planned endovascular interventions (30 superficial femoral arteries and 18 popliteal arteries) were examined with use of common methods on ultrasound portable devise Unison 2-03 with 7,5 MHz linear sensor at all stages of endovascular treatment. The evaluation of hemodynamic indices of blood flow such as peak systolic velocity (PSV), ending diastolic velocity (Ved), medium, velocity of blood flow (Vm), resistivity index (RI), pulsatility index (PI), systole/diastole ratio (S/D) and. degree of stenosis of femoral-popliteal segment arteries before, during and. after X-ray-endovascular interventions was carried out. At intraoperative ultrasound duplex scanning patients had. significant (р < 0,001) decrease if PSV, Ved, Vm. and. the degree of stenosis in comparison with the results of the research before endovascular interventions. Also we registered significant (р < 0,001) decrease of PSV, Ved, Vm. and. the degree of stenosis in patients at ultrasound duplex scanning after endovascular interventions in comparison with the results of the research before operative treatment. There were no significant differences between those indices at ultrasound duplex scanning during and. after endovascular interventions. It was showed that evaluation of condition of lower extremities arteries during ballon angioplasty and. stenting with use of ultrasound duplex scanning allowed, to plan optimum volume and. to improve the results of endovascular operation in each patient individually. At that restoring of geometry and. artery lumina, accuracy of stent positioning, full compliance of stent diameter and. artery in problem zone, absence of stenosis at all or presence of residual stenosis < 25 % and. restoring of main blood flow without local increases of blood flow velocity were the criteria of successful endovascular interventions on femoral-popliteal segment arteries

Hazardous alcohol consumption is associated with increased levels of B-type natriuretic peptide: evidence from two population-based studies.

Russia has very high mortality from cardiovascular disease (CVD), with evidence that heavy drinking may play a role. To throw further light on this association we have studied the association of alcohol with predictors of CVD risk including B-type natriuretic peptide (BNP). Levels of BNP increase primarily in response to abnormal cardiac chamber wall stretch which can occur both as a result of atherosclerosis as well as due to other types of damage to the myocardium. No previous population-based studies have investigated the association with alcohol. We analysed cross-sectional data on drinking behaviour in 993 men aged 25-60 years from the Izhevsk Family Study 2 (IFS2), conducted in the Russian city of Izhevsk in 2008-2009. Relative to non-drinkers, men who drank hazardously had an odds ratio (OR) of being in the top 20 % of the BNP distribution of 4.66 (95 % CI 2.13, 10.19) adjusted for age, obesity, waist-hip ratio, and smoking. Further adjustment for class of hypertension resulted in only slight attenuation of the effect, suggesting that this effect was not secondary to the influence of alcohol on blood pressure. In contrast hazardous drinking was associated with markedly raised ApoA1 and HDL cholesterol levels, but had little impact on levels of ApoB and LDL cholesterol. Similar but less pronounced associations were found in the Belfast (UK) component of the PRIME study conducted in 1991. These findings suggest that the association of heavy drinking with increased risk of cardiovascular disease may be partly due to alcohol-induced non-atherosclerotic damage to the myocardium