Electromechanical Quantum Simulators

Digital quantum simulators are among the most appealing applications of a quantum computer. Here we propose a universal, scalable, and integrated quantum computing platform based on tunable nonlinear electromechanical nano-oscillators. It is shown that very high operational fidelities for single and two qubits gates can be achieved in a minimal architecture, where qubits are encoded in the anharmonic vibrational modes of mechanical nanoresonators, whose effective coupling is mediated by virtual fluctuations of an intermediate superconducting artificial atom. An effective scheme to induce large single-phonon nonlinearities in nano-electromechanical devices is explicitly discussed, thus opening the route to experimental investigation in this direction. Finally, we explicitly show the very high fidelities that can be reached for the digital quantum simulation of model Hamiltonians, by using realistic experimental parameters in state-of-the art devices, and considering the transverse field Ising model as a paradigmatic example.Comment: 14 pages, 8 figure

A basic introduction to ultrastable optical cavities for laser stabilization

We give a simple introduction to the properties and use of ultrastable optical cavities, which are increasingly common in atomic and molecular physics laboratories for stabilizing the frequency of lasers to linewidths at the kHz level or below. Although the physics of Fabry-Perot interferometers is part of standard optics curricula, the specificities of ultrastable optical cavities, such as their high finesse, fixed length, and the need to operate under vacuum, can make their use appear relatively challenging to newcomers. Our aim in this work is to bridge the gap between generic knowledge about Fabry-Perot resonators and the specialized literature about ultrastable cavities. The intended audience includes students setting up an ultrastable cavity in a research laboratory for the first time and instructors designing advanced laboratory courses on optics and laser stabilization techniques.Comment: 10 pages, 8 figures, tutorial article to appear in Am. J . Phy

Transport of Atom Packets in a Train of Ioffe-Pritchard Traps

We demonstrate transport and evaporative cooling of several atomic clouds in a chain of magnetic Ioffe-Pritchard traps moving at a low speed ($<1$~m/s). The trapping scheme relies on the use of a magnetic guide for transverse confinement and of magnets fixed on a conveyor belt for longitudinal trapping. This experiment introduces a new approach for parallelizing the production of Bose-Einstein condensates as well as for the realization of a continuous atom laser

The visible touch: in planta visualization of protein-protein interactions by fluorophore-based methods

Non-invasive fluorophore-based protein interaction assays like fluorescence resonance energy transfer (FRET) and bimolecular fluorescence complementation (BiFC, also referred to as "split YFP") have been proven invaluable tools to study protein-protein interactions in living cells. Both methods are now frequently used in the plant sciences and are likely to develop into standard techniques for the identification, verification and in-depth analysis of polypeptide interactions. In this review, we address the individual strengths and weaknesses of both approaches and provide an outlook about new directions and possible future developments for both techniques

Quantum simulation of the Anderson Hamiltonian with an array of coupled nanoresonators: delocalization and thermalization effects

The possibility of using nanoelectromechanical systems as a simulation tool for quantum many-body effects is explored. It is demonstrated that an array of electrostatically coupled nanoresonators can effectively simulate the Bose-Hubbard model without interactions, corresponding in the single-phonon regime to the Anderson tight-binding model. Employing a density matrix formalism for the system coupled to a bosonic thermal bath, we study the interplay between disorder and thermalization, focusing on the delocalization process. It is found that the phonon population remains localized for a long time at low enough temperatures; with increasing temperatures the localization is rapidly lost due to thermal pumping of excitations into the array, producing in the equilibrium a fully thermalized system. Finally, we consider a possible experimental design to measure the phonon population in the array by means of a superconducting transmon qubit coupled to individual nanoresonators. We also consider the possibility of using the proposed quantum simulator for realizing continuous-time quantum walks.Comment: Replaced with new improved version. To appear in EPJ Q

Comparison of the efficacy of administering a combination of ezetimibe plus fenofibrate versus atorvastatin monotherapy in the treatment of dyslipidemia

<p>Abstract</p> <p>Background</p> <p>This trial compares the efficacy of administering a combination of ezetimibe plus fenofibrate as an alternative to statin monotherapy for the treatment of dyslipidemia. In this randomized, unblinded crossover study, 43 patients with documented hypercholesterolemia requiring pharmacotherapy were randomized to receive six weeks of either a combination of 10 mg of ezetimibe plus 160 mg of fenofibrate (combination) or 10 mg of atorvastatin monotherapy (atorvastatin). The primary endpoint was the percentage reduction of low-density lipoprotein cholesterol (LDL-C).</p> <p>Results</p> <p>LDL-C decreased by 34.6% with the combination therapy versus 36.7% with atorvastatin monotherapy. The difference between the two groups was not statistically significant (p = 0.46). Both study interventions provided similar improvements in total cholesterol (-25.1% with combination versus -24.6% with atorvastatin, p = 0.806) and high-density lipoproteins (+10.0% with combination versus +8.9% with atorvastatin, p = 0.778). Combination therapy showed a trend towards a greater reduction in triglycerides (-25.4% with combination versus -14.5% with atorvastatin, p = 0.079), although there was no significant difference between the two study interventions in terms of the improvement in the TC:HDL ratio (-29.0% with combination versus -28.7% with atorvastatin, p = 0.904).</p> <p>Conclusions</p> <p>The combination of ezetimibe plus fenofibrate appeared to produce nearly identical alterations in serum lipoprotein levels when compared to monotherapy with 10 mg of atorvastatin. Daily treatment with the combination of ezetimibe plus fenofibrate is an acceptable alternative to atorvastatin for the treatment of dyslipidemia in patients who are intolerant of statins.</p

Scissors mode of trapped dipolar gases

We study the scissors modes of dipolar boson and fermion gases trapped in a spherically symmetric potential. We use the harmonic oscillator states to solve the time-dependent Gross-Pitaevskii equation for bosons and the time-dependent Hartree-Fock equation for fermions. It is pointed out that the scissors modes of bosons and fermions can be of quite different nature

Strong coupling between single-electron tunneling and nano-mechanical motion

Nanoscale resonators that oscillate at high frequencies are useful in many measurement applications. We studied a high-quality mechanical resonator made from a suspended carbon nanotube driven into motion by applying a periodic radio frequency potential using a nearby antenna. Single-electron charge fluctuations created periodic modulations of the mechanical resonance frequency. A quality factor exceeding 10^5 allows the detection of a shift in resonance frequency caused by the addition of a single-electron charge on the nanotube. Additional evidence for the strong coupling of mechanical motion and electron tunneling is provided by an energy transfer to the electrons causing mechanical damping and unusual nonlinear behavior. We also discovered that a direct current through the nanotube spontaneously drives the mechanical resonator, exerting a force that is coherent with the high-frequency resonant mechanical motion.Comment: Main text 12 pages, 4 Figures, Supplement 13 pages, 6 Figure

Collective Electronic Excitation Coupling between Planar Optical Lattices using Ewald's Method

Using Ewald's summation method we investigate collective electronic excitations (excitons) of ultracold atoms in parallel planar optical lattices including long range interactions. The exciton dispersion relation can then be suitably rewritten and efficiently calculated for long range resonance dipole-dipole interactions. Such in-plane excitons resonantly couple for two identical optical lattices, with an energy transfer strength decreasing exponentially with the distance between the lattices. This allows a restriction of the transfer to neighboring planes and gives rise to excitons delocalized between the lattices. In general equivalent results will hold for any planar system containing lattice layers of optically active and dipolar materials.Comment: 6 pages, and 7 figure