57 research outputs found
Effects of guanidine on synaptic transmission in the spinal cord of the frog
The effects of guanidine on motoneurons of the isolated frog spinal cord were studied by adding the drug to the solution bathing the cord during intracellular recording. Guanidine (5·10–4 M) did not alter the membrane potential of motoneurons.
The main effect was a marked increase of the amplitudes and frequencies of small spontaneously occurring inhibitory postsynaptic potentials. The hyperpolarizing component of postsynaptic potentials evoked by stimulation of dorsal roots was also enhanced by guanidine. Higher concentrations of guanidine (5·10–3 M) resulted in a very large and irreversible increase of the small spontaneously occurring inhibitory potentials, which now appeared in a regular, rhythmic pattern.
The effects of guanidine could easily be blocked by increasing the magnesium ions (15 mM) in the bath solution.
These results indicate that guanidine facilitates the release of an inhibitory transmitter in afferent terminals of the frog spinal cord either by a direct action on these terminals or indirectly by an action on nerve endings impinging on inhibitory interneurons
Superfluid to Mott insulator transition in one, two, and three dimensions
We have created one-, two-, and three-dimensional quantum gases and study the
superfluid to Mott insulator transition. Measurements of the transition using
Bragg spectroscopy show that the excitation spectra of the low-dimensional
superfluids differ significantly from the three-dimensional case
The Long-Term Care System in Germany
This document provides an overview of the long-term care system, the number and develop-ment of beneficiaries and the long-term care policy in Germany. The report is part of the first stage of the European project ANCIEN (Assessing Needs of Care in European Nations), commissioned by the European Commission under the Seventh Framework Programme (FP7). The first part of the project aims to facilitate structured comparison of the long-term care systems and policies in European Nations. Thus, this report is one of comparable reports provided for most European countries
Long-Term Effects of Diabetes Prevention: Evaluation of the M.O.B.I.L.I.S. Program for Obese Persons
Zur Differenzierung von Plasma- und Myelomzellen des Menschen Kombinierte plani- und zytophotometrische Messungen
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