Crosslinking in the complex treatment of corneal ulceration and corneal grafting

Purpose: to study the impact of crosslinking (CL) on the healing of corneal ulcers of various etiologies. Materials and methods. Treatment results of 15 patients with corneal and transplant ulcers by CL and its combination with other surgical interventions were analyzed. Results. For the first time three options of combined treatment of corneal ulcers were proposed: 1) CL as an independent method; 2) CL combined with transplantation of amniotic membrane (ТАМ) and temporary tarsorrhaphy; 3) corneal grafting combined with CL. The main diagnostic technique of treatment result evaluation was OCT of the anterior segment of the eye. Results. CL was found to contribute to the cleaning of the bottom and the edges of the ulcer surface, to promote the resorption of the hypopyon and the edema, leads to rapid healing of the ulcer and the reduction of the corneal syndrome and increases visual acuity. Conclusion. The obtained data indicate the need for further study of the impact of CL on the healing process of corneal and transplant ulcers. For citations: Chentsova E.V., Verigo E.N., Makarov P.V., Khazamova A.I. Crosslinking in the complex treatment of corneal ulceration and corneal grafting. Russian ophthalmological journal. 2017; 10 (3): 93-100. doi: 10.21516/2072-0076-2017-10-3-93-100 (in Russian)