408 research outputs found
Entanglement distillation by adiabatic passage in coupled quantum dots
Adiabatic passage of two correlated electrons in three coupled quantum dots
is shown to provide a robust and controlled way of distilling, transporting and
detecting spin entanglement, as well as of measuring the rate of spin
disentanglement. Employing tunable interdot coupling the scheme creates, from
an unentangled two-electron state, a superposition of spatially separated
singlet and triplet states. A single measurement of a dot population (charge)
collapses the wave function to either of these states, realizing entanglement
to charge conversion. The scheme is robust, with the efficiency close to 100%,
for a large range of realistic spectral parameters.Comment: 5 pages, 4 figure
Atom interferometry with trapped Bose-Einstein condensates: Impact of atom-atom interactions
Interferometry with ultracold atoms promises the possibility of ultraprecise
and ultrasensitive measurements in many fields of physics, and is the basis of
our most precise atomic clocks. Key to a high sensitivity is the possibility to
achieve long measurement times and precise readout. Ultra cold atoms can be
precisely manipulated at the quantum level, held for very long times in traps,
and would therefore be an ideal setting for interferometry. In this paper we
discuss how the non-linearities from atom-atom interactions on one hand allow
to efficiently produce squeezed states for enhanced readout, but on the other
hand result in phase diffusion which limits the phase accumulation time. We
find that low dimensional geometries are favorable, with two-dimensional (2D)
settings giving the smallest contribution of phase diffusion caused by
atom-atom interactions. Even for time sequences generated by optimal control
the achievable minimal detectable interaction energy is on
the order of 0.001 times the chemical potential of the BEC in the trap. From
there we have to conclude that for more precise measurements with atom
interferometers more sophisticated strategies, or turning off the interaction
induced dephasing during the phase accumulation stage, will be necessary.Comment: 28 pages, 13 figures, extended and correcte
Mach-Zehnder interferometry with interacting trapped Bose-Einstein condensates
We theoretically analyze a Mach-Zehnder interferometer with trapped
condensates, and find that it is surprisingly stable against the nonlinearity
induced by inter-particle interactions. The phase sensitivity, which we study
for number squeezed input states, can overcome the shot noise limit and be
increased up to the Heisenberg limit provided that a Bayesian or
Maximum-Likelihood phase estimation strategy is used. We finally demonstrate
robustness of the Mach-Zehnder interferometer in presence of interactions
against condensate oscillations and a realistic atom counting error.Comment: 4 pages, 5 figures, minor revision
Exploiting exciton-exciton interactions in semiconductor quantum dots for quantum-information processing
We propose an all-optical implementation of quantum-information processing in
semiconductor quantum dots, where electron-hole excitations (excitons) serve as
the computational degrees of freedom (qubits). We show that the strong dot
confinement leads to an overall enhancement of Coulomb correlations and to a
strong renormalization of the excitonic states, which can be exploited for
performing conditional and unconditional qubit operations.Comment: 5 pages revtex, 2 encapsulated postscript figures. Accepted for
publication in Phys. Rev. B (Rapid Communication
Optical excitations of a self assembled artificial ion
By use of magneto-photoluminescence spectroscopy we demonstrate bias
controlled single-electron charging of a single quantum dot. Neutral, single,
and double charged excitons are identified in the optical spectra. At high
magnetic fields one Zeeman component of the single charged exciton is found to
be quenched, which is attributed to the competing effects of tunneling and
spin-flip processes. Our experimental data are in good agreement with
theoretical model calculations for situations where the spatial extent of the
hole wave functions is smaller as compared to the electron wave functions.Comment: to be published in Physical Review B (rapid communication
Phase Estimation from Atom Position Measurements
We study the measurement of the position of atoms as a means to estimate the
relative phase between two Bose-Einstein condensates. First, we consider
atoms released from a double-well trap, forming an interference pattern, and
show that a simple least-squares fit to the density gives a shot-noise limited
sensitivity. The shot-noise limit can instead be overcome by using correlation
functions of order or larger. The measurement of the
-order correlation function allows to estimate the relative phase
at the Heisenberg limit. Phase estimation through the measurement of the
center-of-mass of the interference pattern can also provide sub-shot-noise
sensitivity. Finally, we study the effect of the overlap between the two clouds
on the phase estimation, when Mach-Zehnder interferometry is performed in a
double-well.Comment: 20 pages, 6 figure
Optimal control of number squeezing in trapped Bose-Einstein condensates
We theoretically analyze atom interferometry based on trapped ultracold
atoms, and employ optimal control theory in order to optimize number squeezing
and condensate trapping. In our simulations, we consider a setup where the
confinement potential is transformed from a single to a double well, which
allows to split the condensate. To avoid in the ensuing phase-accumulation
stage of the interferometer dephasing due to the nonlinear atom-atom
interactions, the atom number fluctuations between the two wells should be
sufficiently low. We show that low number fluctuations (high number squeezing)
can be obtained by optimized splitting protocols. Two types of solutions are
found: in the Josephson regime we find an oscillatory tunnel control and a
parametric amplification of number squeezing, while in the Fock regime
squeezing is obtained solely due to the nonlinear coupling, which is
transformed to number squeezing by peaked tunnel pulses. We study splitting and
squeezing within the frameworks of a generic two-mode model, which allows us to
study the basic physical mechanisms, and the multi-configurational time
dependent Hartree for bosons method, which allows for a microscopic modeling of
the splitting dynamics in realistic experiments. Both models give similar
results, thus highlighting the general nature of these two solution schemes. We
finally analyze our results in the context of atom interferometry.Comment: 17 pages, 21 figures, minor correction
Biliary Bicarbonate Secretion Constitutes a Protective Mechanism against Bile Acid-Induced Injury in Man
Background: Cholangiocytes expose a striking resistance against bile acids: while other cell types, such as hepatocytes, are susceptible to bile acid-induced toxicity and apoptosis already at micromolar concentrations, cholangiocytes are continuously exposed to millimolar concentrations as present in bile. We present a hypothesis suggesting that biliary secretion of HCO(3)(-) in man serves to protect cholangiocytes against bile acid-induced damage by fostering the deprotonation of apolar bile acids to more polar bile salts. Here, we tested if bile acid-induced toxicity is pH-dependent and if anion exchanger 2 (AE2) protects against bile acid-induced damage. Methods: A human cholangiocyte cell line was exposed to chenodeoxycholate (CDC), or its glycine conjugate, from 0.5 mM to 2.0 mM at pH 7.4, 7.1, 6.7 or 6.4, or after knockdown of AE2. Cell viability and apoptosis were determined by WST and caspase-3/-7 assays, respectively. Results: Glycochenodeoxycholate (GCDC) uptake in cholangiocytes is pH-dependent. Furthermore, CDC and GCDC (pK(a) 4-5) induce cholangiocyte toxicity in a pH-dependent manner: 0.5 mM CDC and 1 mM GCDC at pH 7.4 had no effect on cell viability, but at pH 6.4 decreased viability by >80% and increased caspase activity almost 10- and 30-fold, respectively. Acidification alone had no effect. AE2 knockdown led to 3- and 2-fold enhanced apoptosis induced by 0.75 mM CDC or 2 mM GCDC at pH 7.4. Discussion: These data support our hypothesis of a biliary HCO(3)(-) umbrella serving to protect human cholangiocytes against bile acid-induced injury. AE2 is a key contributor to this protective mechanism. The development and progression of cholangiopathies, such as primary biliary cirrhosis, may be a consequence of genetic and acquired functional defects of genes involved in maintaining the biliary HCO(3)(-) umbrella. Copyright (C) 2011 S. Karger AG, Base
Spin flip lifetimes in superconducting atom chips: BCS versus Eliashberg theory
We investigate theoretically the magnetic spin-flip transitions of neutral
atoms trapped near a superconducting slab. Our calculations are based on a
quantum-theoretical treatment of electromagnetic radiation near dielectric and
metallic bodies. Specific results are given for rubidium atoms near a niobium
superconductor. At the low frequencies typical of the atomic transitions, we
find that BCS theory greatly overestimates coherence effects, which are much
less pronounced when quasiparticle lifetime effects are included through
Eliashberg theory. At 4.2 K, the typical atomic spin lifetime is found to be
larger than a thousand seconds, even for atom-superconductor distances of one
micrometer. This constitutes a large enhancement in comparison with normal
metals.Comment: 10 pages, 4 figure
Molecular mechanism of decision-making in glycosaminoglycan biosynthesis
Two major glycosaminoglycan types, heparan sulfate (HS) and chondroitin sulfate (CS), control many aspects of development and physiology in a type-specific manner. HS and CS are attached to core proteins via a common linker tetrasaccharide, but differ in their polymer backbones. How core proteins are specifically modified with HS or CS has been an enduring mystery. By reconstituting glycosaminoglycan biosynthesis in vitro, we establish that the CS-initiating N-acetylgalactosaminyltransferase CSGALNACT2 modifies all glycopeptide substrates equally, whereas the HS-initiating N-acetylglucosaminyltransferase EXTL3 is selective. Structure-function analysis reveals that acidic residues in the glycopeptide substrate and a basic exosite in EXTL3 are critical for specifying HS biosynthesis. Linker phosphorylation by the xylose kinase FAM20B accelerates linker synthesis and initiation of both HS and CS, but has no effect on the subsequent polymerisation of the backbone. Our results demonstrate that modification with CS occurs by default and must be overridden by EXTL3 to produce HS
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