39 research outputs found
Texture evolution during deep-drawing processes
peer reviewedThis paper presents a constitutive law based on Taylor’s model implemented in our non-linear finite element code LAGAMINE. The yield locus is only locally described and a particular interpolation method has been developed. This local yield locus model uses a discrete
representation of the material’s texture. The interpolation method is presented and a deep-drawing application is simulated in order to show up the influence of the texture evolution during forming processes
Allogeneic Hematopoietic Stem Cell Transplantation After Prior Lung Transplantation for Hereditary Pulmonary Alveolar Proteinosis: A Case Report
Pulmonary alveolar proteinosis (PAP) is a rare, diffuse lung disorder characterized by surfactant accumulation in the small airways due to defective clearance by alveolar macrophages, resulting in impaired gas exchange. Whole lung lavage is the current standard of care treatment for PAP. Lung transplantation is an accepted treatment option when whole lung lavage or other experimental treatment options are ineffective, or in case of extensive pulmonary fibrosis secondary to PAP. A disadvantage of lung transplantation is recurrence of PAP in the transplanted lungs, especially in hereditary PAP. The hereditary form of PAP is an ultra-rare condition caused by genetic mutations in genes encoding for the granulocyte macrophage-colony stimulating factor (GM-CSF) receptor, and intrinsically affects bone marrow derived-monocytes, which differentiate into macrophages in the lung. Consequently, these macrophages typically display disrupted GM-CSF receptor-signaling, causing defective surfactant clearance. Bone marrow/hematopoietic stem cell transplantation may potentially reverse the lung disease in hereditary PAP. In patients with hereditary PAP undergoing lung transplantation, post-lung transplant recurrence of PAP may theoretically be averted by subsequent hematopoietic stem cell transplantation, which results in a graft-versus-disease (PAP) effect, and thus could improve long-term outcome. We describe the successful long-term post-transplant outcome of a unique case of end-stage respiratory failure due to hereditary PAP-induced pulmonary fibrosis, successfully treated by bilateral lung transplantation and subsequent allogeneic hematopoietic stem cell transplantation. Our report supports treatment with serial lung and hematopoietic stem cell transplantation to improve quality of life and prolong survival, without PAP recurrence, in selected patients with end-stage hereditary PAP
Micro-macro analysis of steel sheet behaviour in finite element simulations. Application to deep-drawing process.
peer reviewedThis paper presents a constitutive law based on Taylor’s model implemented in our non-linear finite element code LAGAMINE. The yield locus is only locally described and a particular interpolation method has been developed. This local yield locus model uses a discrete representation of the material’s texture. The interpolation method is presented and a deep-drawing application is simulated in order to show up the influence of the texture
evolution during forming processes
Development of a contact model adapted to incremental forming
peer reviewedThe objective of this article is to present the development of a new method for taking into
account the contact between the tool and the blank during incremental forming. First, the need for such a model is justified. Then, the basic features of the adapted dynamic explicit scheme are presented, followed by the new algorithms proposed and their programming. Finally, some conclusions and perspectives are drawn
Validation of a FEM model coupled with texture applied to deep drawing process
peer reviewedThis paper presents a constitutive law based on the Taylor model implemented in our non linear finite element code LAGAMINE. The yield locus is only locally described and the interpolation method is presented. This local yield locus model uses a discrete representation of the material's texture. The influence of this discrete representation and a deep-drawing simulation are presented
Implementation of a texture based interpolated yield locus in a FEM code
peer reviewedThis paper presents a constitutive law based on Taylor's model implemented in our non linear finite element code LAGAMINE. The yield locus is only described and a particular interpolation method has been developed. This local yield locus model uses a discrete representation of the material's texture. The interpolation method is presented and a deep-drawing application is simulated in order to show up the influence of the texture evolution during forming processes
Influence of steel anisotropy during deep-drawing process
peer reviewedThis paper presents a constitutive law based on Taylor's model implemented in our finite element code LAGAMINE. The yield locus is only locally described and a particular interpolation method has been developed. This local yield locus model uses a discrete representation of the texture. The interpolation method is presented and a deep-drawing application is simulated in order to show up the influence of the texture evolution during forming processes
Modelling of the micro-mechanical behaviour of steel sheets during deep-drawing
peer reviewedThis abstract presents a constitutive law based on Taylor's model implemented in our non-linear finite element code LAGAMINE. The yield locus is only locally described and a particular interpolation method has been developed. This local yield locus model uses a discrete representation of the material's texture. The interpolation method is presented and a deep-drawing application is simulated in order to show up the influence of the texture evolution during forming processes