Sexual Minority Women and Alcohol: Intersections between drinking, relational contexts, stress, and coping

Few studies explore sexual-minority women\u27s experiences and perceptions of alcohol. Qualitative interviews were conducted with six sexual-minority women who reported having sought help for alcohol problems in the past and six who did not. Themes emerged in two broad areas: (1) stressors that contributed to heavy or problem drinking and (2) factors that enhanced coping and reduced both stress and problem use. Alcohol use across groups was framed in terms of social context (e.g., bar patronage), stress management, and addiction. The findings of the study underscore the importance of considering the role of alcohol in managing stress as well as coping factors that may inform social service interventions

SUPERVISED CANCER REHABILITATION: APPLICATIONS FOR UTILIZING EXISTING CARDIOPULMONARY REHABILITATION FACILITIES FOR CANCER PATIENTS AND SURVIVORS

Currently, the NIH reports there are approximately 18 million Americans with a history of cancer. Cancer statistics are projected to rise to 22.1 million by 2030. In addition to cancer, cardiovascular diseases are globally the leading causes of mortality and morbidity. The body of research in this area clearly demonstrates that greater amounts of physical activity correspond with a lower risk of cancer recurrence and all-cause mortality, including cardiovascular disease (CVD). Exercise rehabilitation success in cancer patients, both during and after treatment, is limited by several barriers, including the lack of facilities, trained personnel and financial resources. In response to this medical need, it seems logical for oncology patients to be able to utilize current cardiac rehabilitation models. Cardio-oncology rehabilitation is a multi-component exercise-based intervention. Current projections suggest that few adjustments to current cardiac rehabilitation models would be needed to address the oncology rehabilitation model, although strategic differences to be addressed include addressing the adverse effects from certain chemotherapies, surgical interventions and lymphedema. Secondary to this narrative, there exists a bidirectional relationship between these two leading chronic diseases: in that cardiovascular diseases increase the likelihood of getting cancer and vice versa. Accordingly, use of cardiac facilities may extend the benefits of exercise beyond therapeutic applications to cancer, in that potential concerns related to CVD could also be addressed. Based on this rationale, the purpose of this professional paper will explore the utilization of existing staff and equipment currently being used in cardiopulmonary rehabilitation (CPR) field and how that can be utilized concomitantly with oncology rehabilitation populations

Media(ted) fabrications: How the science-media symbiosis helped ‘sell’ cord banking

This paper considers the problematic role of the science–media symbiosis in the dissemination of misleading and emotionally manipulative information regarding services offered by CordBank, New Zealand's only umbilical cord blood banking facility. As this case study illustrates, the growing reliance of health and science reporters on the knowledge capital of medical specialists, biogenetic researchers, and scientists potentially enhances the ability of ‘expert’ sources to set the agenda for media representations of emerging medical and scientific developments, and may undermine the editorial independence of journalists and editors, many of whom in this case failed to critically evaluate deeply problematic claims regarding the current and future benefits of cord banking. Heavy reliance on established media frames of anecdotal personalization and technoboosterism also reinforced a proscience journalistic culture in which claims by key sources were uncritically reiterated and amplified, with journalistic assessments of the value of cord banking emphasizing potential benefits for individual consumers. It is argued that use of these media frames potentially detracts from due consideration of the broader social, ethical, legal, and health implications of emerging biomedical developments, along with the professional, personal, and increasingly also financial interests at stake in their public promotion, given the growing commercialization of biogenetic technologies

A spatially explicit model for tropical tree diversity patterns

A complex two-parameter model resembling the classical voter model is introduced to describe macroecological properties of tropical tree communities. Monte-Carlo type computer simulations are performed on the model, investigating species abundances and the spatial distribution of individuals and species. Simulation results are critically compared with the experimental data obtained from a tree census on a 50 hectares area of the Barro Colorado Island (BCI), Panama. The model parameters are optimized for reproducing quantitatively the experimental results from the BCI dataset.Comment: 8 pages, 12 figure

A seed-diffusion model for tropical tree diversity patterns

Diversity patterns of tree species in a tropical forest community are approached by a simple lattice model and investigated by Monte Carlo simulations using a backtracking method. Our spatially explicit neutral model is based on a simple statistical physics process, namely the diffusion of seeds. The model has three parameters: the speciation rate, the size of the meta-community in which the studied tree-community is embedded, and the average surviving time of the seeds. By extensive computer simulations we aim the reproduction of relevant statistical measures derived from the experimental data of the Barro Colorado Island tree census in year 1995. The first two parameters of the model are fixed to known values, characteristic of the studied community, thus obtaining a model with only one freely adjustable parameter. As a result of this, the average number of species in the considered territory, the relative species abundance distribution, the species-area relationship and the spatial auto-correlation function of the individuals in abundant species are simultaneously fitted with only one parameter which is the average surviving time of the seeds.Comment: 12 pages, 5 figure

Functional Traits of Tropical Trees and Lianas Explain Spatial Structure across Multiple Scales

Dispersal and density dependence are major determinants of spatial structure, population dynamics and coexistence for tropical forest plants. However, because these two processes can jointly influence spatial structure at similar scales, analysing spatial patterns to separate and quantify them is often difficult. Species functional traits can be useful indicators of dispersal and density dependence. However, few methods exist for linking functional traits to quantitative estimates of these processes that can be compared across multiple species. We analysed static spatial patterns of woody plant populations in the 50 ha Forest Dynamics Plot on Barro Colorado Island, Panama with methods that distinguished scale‐specific differences in species aggregation. We then tested how these differences related to seven functional traits: growth form, dispersal syndrome, tree canopy layer, adult stature, seed mass, wood density and shade tolerance. Next, we fit analytically tractable spatial moment models to the observed spatial structure of species characterized by similar trait values, which allowed us to estimate relationships of functional traits with the spatial scale of dispersal, and the spatial scale and intensity of negative density dependence. Our results confirm that lianas are more aggregated than trees, and exhibit increased aggregation within canopy gaps. For trees, increased seed mass, wood density and shade tolerance were associated with less intense negative density dependence, while higher canopy layers and increased stature were associated with decreased aggregation and better dispersal. Spatial structure for trees was also strongly determined by dispersal syndrome. Averaged across all spatial scales, zoochory was more effective than wind dispersal, which was more effective than explosive dispersal. However, at intermediate scales, zoochory was associated with more aggregation than wind dispersal, potentially because of differences in short‐distance dispersal and the intensity of negative density dependence. Synthesis. We develop new tools for identifying significant associations between functional traits and spatial structure, and for linking these associations to quantitative estimates of dispersal scale and the strength and scale of density dependence. Our results help clarify how these processes influence woody plant species on Barro Colorado, and demonstrate how these tools can be applied to other sites and systems

Angiotensin-converting enzyme activity and inhibition in dogs with cardiac disease and an angiotensin-converting enzyme polymorphism

OBJECTIVE The objective of this study was to evaluate angiotensin-converting enzyme (ACE) activity in dogs and with and without an ACE polymorphism in the canine ACE gene, before and after treatment with an ACE inhibitor. METHODS Thirty-one dogs (20 wild-type, 11 ACE polymorphism) with heart disease were evaluated with ACE activity measurement and systolic blood pressure before and after administration of an ACE inhibitor (enalapril). RESULTS Median pre-treatment ACE activity was significantly lower for ACE polymorphism dogs than for dogs with the wild-type sequence ( P=0.007). After two weeks of an ACE inhibitor, ACE activity was significantly reduced for both genotypes (wild-type, P<0.0001; ACE polymorphism P=0.03); mean post-therapy ACE activity was no different between the groups. CONCLUSION An ACE polymorphism is associated with lower levels of ACE activity. Dogs with the polymorphism still experience suppression of ACE activity in response to an ACE inhibitor. It is possible that the genetic status and ACE activity of dogs may impact the response of dogs with this variant to an ACE inhibitor

Metaphors in search of a target: the curious case of epigenetics

Carrying out research in genetics and genomics and communicating about them would not be possible without metaphors such as "information," "code," "letter" or "book." Genetic and genomic metaphors have remained relatively stable for a long time but are now beginning to shift in the context of synthetic biology and epigenetics. This article charts the emergence of metaphors in the context of epigenetics, first through collecting some examples of metaphors in scientific and popular writing and second through a systematic analysis of metaphors used in two UK broadsheets. Findings show that while source domains for metaphors can be identified, such as our knowledge of electrical switches or of bookmarks, it is difficult to pinpoint target domains for such metaphors. This may be indicative both of struggles over what epigenetics means for scientists (natural and social) and of difficulties associated with talking about this, as yet, young field in the popular press