632 research outputs found
L'esecuzione nei contratti di appalto di opere pubbliche
Viene decritta la normativa relativa alla gestione del contratto d'appalto pubblico a sèguito delle riforme operate dal III Decreto correttivo e dal Decreto di recepimento della cd. Direttiva Ricorsi
On the dynamical behavior of the ABC model
We consider the ABC dynamics, with equal density of the three species, on the
discrete ring with sites. In this case, the process is reversible with
respect to a Gibbs measure with a mean field interaction that undergoes a
second order phase transition. We analyze the relaxation time of the dynamics
and show that at high temperature it grows at most as while it grows at
least as at low temperature
The effects of robotic assistance on upper limb spatial muscle synergies in healthy people during planar upper-limb training
Background Robotic rehabilitation is a commonly adopted technique used to restore motor functionality of neurological patients. However, despite promising results were achieved, the effects of human-robot interaction on human motor control and the recovery mechanisms induced with robot assistance can be further investigated even on healthy subjects before translating to clinical practice. In this study, we adopt a standard paradigm for upper-limb rehabilitation (a planar device with assistive control) with linear and challenging curvilinear trajectories to investigate the effect of the assistance in human-robot interaction in healthy people. Methods Ten healthy subjects were instructed to perform a large set of radial and curvilinear movements in two interaction modes: 1) free movement (subjects hold the robot handle with no assistance) and 2) assisted movement (with a force tunnel assistance paradigm). Kinematics and EMGs from representative upper-limb muscles were recorded to extract phasic muscle synergies. The free and assisted interaction modes were compared assessing the level of assistance, error, and muscle synergy comparison between the two interaction modes. Results It was found that in free movement error magnitude is higher than with assistance, proving that task complexity required assistance also on healthy controls. Moreover, curvilinear tasks require more assistance than standard radial paths and error is higher. Interestingly, while assistance improved task performance, we found only a slight modification of phasic synergies when comparing assisted and free movement. Conclusions We found that on healthy people, the effect of assistance was significant on task performance, but limited on muscle synergies. The findings of this study can find applications for assessing human-robot interaction and to design training to maximize motor recovery
Systematic perturbation approach for a dynamical scaling law in a kinetically constrained spin model
The dynamical behaviours of a kinetically constrained spin model
(Fredrickson-Andersen model) on a Bethe lattice are investigated by a
perturbation analysis that provides exact final states above the nonergodic
transition point. It is observed that the time-dependent solutions of the
derived dynamical systems obtained by the perturbation analysis become
systematically closer to the results obtained by Monte Carlo simulations as the
order of a perturbation series is increased. This systematic perturbation
analysis also clarifies the existence of a dynamical scaling law, which
provides a implication for a universal relation between a size scale and a time
scale near the nonergodic transition.Comment: 17 pages, 7 figures, v2; results have been refined, v3; A figure has
been modified, v4; results have been more refine
Lezioni di Legislazione delle Opere Pubbliche
La pubblicazione raccoglie le lezioni universitarie tenute da Cancrini e Capuzza nella facoltà di Igegneria: descrive gli istituti fondamentali della normativa dopo l'entrata in vigore del D.Lsg. n. 163/2006, alla luce delle Direttive dell'U.E. n. 17 e n. 18 del 2004
Exclusion processes with degenerate rates: convergence to equilibrium and tagged particle
Stochastic lattice gases with degenerate rates, namely conservative particle
systems where the exchange rates vanish for some configurations, have been
introduced as simplified models for glassy dynamics. We introduce two
particular models and consider them in a finite volume of size in
contact with particle reservoirs at the boundary. We prove that, as for
non--degenerate rates, the inverse of the spectral gap and the logarithmic
Sobolev constant grow as . It is also shown how one can obtain, via a
scaling limit from the logarithmic Sobolev inequality, the exponential decay of
a macroscopic entropy associated to a degenerate parabolic differential
equation (porous media equation). We analyze finally the tagged particle
displacement for the stationary process in infinite volume. In dimension larger
than two we prove that, in the diffusive scaling limit, it converges to a
Brownian motion with non--degenerate diffusion coefficient.Comment: 25 pages, 3 figure
Consanguinity and polygenic diseases: a model for antibody deficiencies
Primary immunodeficiencies represent a heterogeneous group of disorders of the immune system, predisposing to various types of infections. Among them, common variable immunodeficiency is the most common symptomatic antibody deficiency. It includes several different forms characterized by defects in the terminal stage of B lymphocyte differentiation, leading to markedly reduced immunoglobulin serum levels and increased susceptibility to bacterial infections. The clinical phenotype is complex, including autoimmunity, granulomatous inflammation, lymphoproliferative disorders and malignancies. Rare autosomal recessive mutations in a number of single genes have recently been reported. However, the underlying genetic defects remain unknown in the majority of cases. In order to seek new genes responsible for the disease, we studied a consanguineous Italian family through exome sequencing combined with homozygosity mapping. Six missense homozygous variants passed our filtering selection and at least two of them were associated with some aspects of the pathological phenotype. Our data remark the complexity of immune system disorders and emphasize the difficulty to understand the significance of genetic results and their correlation with the disease phenotype
Dog filariosis in the Lazio region (Central Italy): first report on the presence of Dirofilaria repens
BACKGROUND: Epidemiological investigations were carried out in the Lazio Region to assess the status of canine filariosis and to evaluate the actual risk for veterinary and medical public health. METHODS: Since August 2001 to June 2003, a total of 972 canine blood samples, collected in public kennels and from private owners animals of the 5 Provinces of the Region, were tested. The presence of filarial parasites was evaluated by microscopy and bio-molecular techniques; the species identification was performed by means of the same diagnostic tools. RESULTS: A total of 17/972 (1.75%; 95%CI 1.06%–2.85%) blood samples were parasitized by D. repens,13 out them drawn by dogs resident in the Province of Roma, and 4 in the other provinces. Multivariate analysis was performed in order to evaluate the association between filariosis and risk factors. The origin from coastal territories seems to be a significant risk factor to acquire the infection. CONCLUSION: This is the first report of canine filariosis in the Lazio Region, where D. repens was before reported only in foxes. The risk of human zoonotic infection is stressed, and the absence of other filarial species is discusse
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