Susceptibility of Yeast-Like Fungi to a New Antifungal Agent, LY 121019

LY 121019, a new antifungal antibiotic agent, was tested for activity against 200 clinical isolates of Candida and other yeast-like fungi. LY 121019 had its greatest inhibitory effect on C. albicans , and C. tropicalis. C. glabrata and most other Candida species were not as sensitive. Cryptococcus and other yeast-like fungi, with the exception of a few strains, were not susceptible to LY 121019. Zusammenfassung :  LY 121019, ein neues Antimyzetikum, wurde auf seine AktivitÄt gegen 200 klinische Isolate von Candida und anderen, hefeÄhnlichen Pilzen untersucht. LY 121019 hat seine grÖßte Hemmwirkung gegen C. albicans und C. tropicalis. C. glabrata und die meisten anderen Candida -Arten waren nicht so empfindlich. Cryptococcus und andere, hefeÄhnliche Pilze waren, mit Ausnahme weniger StÄmme, nicht fÜr LY 121019 empfindlich.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73892/1/j.1439-0507.1988.tb04426.x.pd

CMBMeTest: Generation of Test Suites Using Model-Based Testing Plus Constraint Programming and Metamorphic Testing

Various software testing techniques have been shown to be successful in producing high-quality test suites for software where the code is not accessible (black-box approach). Nevertheless, no method has been found to guide combining some of these in a general way. In this study, a test suite generation method for black-box software called CMBMeTest was created to respond to these challenges. It employs several coupled software testing techniques, namely, model-based testing (MBT), constraint programming (CP), and metamorphic testing (MT). CMBMeTest provides step-by-step instructions for using the information available (such as program specifications, inputs and outputs) to create an initial test suite that covers the model obtained, using a combination of MBT and CP (referred to as MBT+CP). Furthermore, using the metamorphic relations (MRs) of MT, a better test suite was produced from that initial test suite. The method allows particular stages to be iterated to improve the results by building new models and new MRs. A comprehensive case study was conducted, employing CMBMeTest to produce encouraging results. Mutation testing was used to evaluate the test suite, and the first round produced a high mutation score. A more detailed model was used to repeat the process, with similar outcomes.25 página

Applying the data envelopment analysis method for evaluating the efficiency of the complex system operations in fuel and energy companies

This work proposes the Data Envelopment Analysis method (DEA) as a tool for evaluating the efficiency of the complex systems operations on the example of fuel and energy companies. It is also presented a comparative analysis of different methods for evaluating the efficiency of the complex systems operations. The output-oriented DEA model is used in the research. The task with one input and two outputs is solved. In order to test the method, a complex system was chosen – the heat supply system for the heat and power plants on the left bank of Krasnoyarsk. The calculations were made using four heat and power plants in Krasnoyarsk

The Effect of Intrinsic and Extrinsic Motivation on Employee Performance at 21cineplex, Manado

Entertainment is a form of activity that holds the attention and interest of audience, or gives pleasure and delight. One of the entertainment parts is cinema. Cinema, or motion picture, is the art of moving images or a visual medium that tells stories and exposes reality. Today there is a lot of young generation in Indonesia goes to cinemas for watching movie and hangout. Considering Manado people who are movie goers and willing to spend their money in cinemas. Those showing cinemas are one of profitable business in Manado. One of the important factors that make this business increase is a good service from the employee of cinemas. This research use causal type of research where it will investigate the effect of extrinsic and intrinsic motivation on employee performance at Cinemas (Studio 21, and Theater XXI) in Manado. This research used Saturating sampling method. This research used population as the data sources to make an appropriate result of data.This research found the effect of Intrinsic and Extrinsic Motivation on Employee Performance at 21Cineplex, Manado. In this case Extrinsic Motivation is more important than Intrinsic Motivation. So the result is Extrinsic Motivation become the best starategy to boost employee performance at 21Cineplex, Manado, which is they give bonus, sallary, promotion, and other things that conected with Extrinsic Motivation

Propuesta metodológica para la implementación de una arquitectura orientada a servicios en entornos de Sistemas de Fabricación Distribuida

Los Sistemas de Fabricación de Siguiente Generación, concebidos por la organización IMS (Intelligent Manufacturing Systems), cubrirán la demanda de un mercado cada vez más cambiante y exigente, reuniendo de forma dinámica las funciones de múltiples sistemas internos y externos a la propia empresa de fabricación en lo que conocemos por una empresa extendida. Sin embargo, resulta difícil estructurar estos sistemas para conseguir la flexibilidad deseada y la interoperabilidad con los de las demás organizaciones. Además, un defecto en el sistema tendría un fuerte impacto: afectaría no sólo a la empresa propietaria del sistema, sino también a sus colaboradores. Por estas razones, creemos que una buena decisión sería emplear una arquitectura orientada a servicios diseñada siguiendo una metodología que adopte los servicios como concepto central, en vez de como un detalle de implementación. Para que la arquitectura sea fiable en su conjunto, tendrá que ayudar a localizar errores antes de que sucedan en un entorno de producción. En este artículo proponemos el uso de técnicas de pruebas específicas para este tipo de sistemas, realizamos una comparación de las metodologías existentes para el desarrollo de arquitecturas orientadas a servicios y esbozamos una serie de extensiones sobre una de las existentes para integrar técnicas de prueba.As envisioned by the IMS (Intelligent Manufacturing Systems), Next Generation Manufacturing Systems will satisfy the needs of an increasingly fast-paced and demanding market by dynamically integrating systems from inside and outside the manufacturing firm itself into a so-called extended enterprise. However, organizing these systems to ensure the maximum flexibility and interoperability with those from other organizations is difficult. Additionally, a defect in the system would have a great impact: it would affect not only its owner, but also its partners. For these reasons, we argue that a service-oriented architecture (SOA) would be a good candidate. It should be designed following a methodology where services play a central role, instead of being an implementation detail. In order for the architecture to be reliable enough as a whole, the methodology will need to help find errors before they arise in a production environment. In this paper we propose using SOA-specific testing techniques, compare some of the existing SOA methodologies and outline several extensions upon one of them to integrate testing techniques

Evaluating the efficiency of heat and power systems by the data envelopment analysis method

The article describes the Data Envelopment Analysis (DEA) method and the main features of its application. The main problems of heat and power systems are described, which are addressed by the DEA method of efficiency assessment presented in the article. The approbation of this method is presented at the objects of the centralized municipal heat supply system of the fuel and energy complex: boiler houses and heat and power plants. 9 objects were analyzed according to four input indicators: available heat capacity, installed heat capacity, heat consumption for own needs, fuel consumption. Also, the efficiency of the system was evaluated according to two output indicators: the release of thermal energy to the grid and the mass of the emission. As a result of the analysis and calculations made, it was revealed that 5 objects have the maximum possible efficiency indicator equal to 1, that is, they function as efficiently as possible. 4 objects of the centralized municipal heat supply system have an efficiency indicator less than 1. Accordingly, improvements are required for the operation of the above Decision-Making Units (DMU)s. These objects have deviations in terms of the inputs and outputs of the actual data and those obtained using the DEA method. Based on the calculations obtained for these 4 objects, the article provides recommendations for changing the quantitative values of their input and output indicators. For example, for object number 2, it is recommended to reduce the installed heat capacity in the grid by 72.57%, without changing the available heat capacity and fuel consumption. Reduce the heat consumption for your own needs by 69.383%. In addition, it is recommended to increase the supply of thermal energy to the grid by 6,034%, and reduce the mass of emission by 11.5%. Specific measures have also been developed to modernize the studied objects in order to achieve the recommended indicators of inputs and outputs. The research results presented in the article are of scientific and practical interest and can be used to improve the efficiency of heat and power systems facilities. © 2021, World Scientific and Engineering Academy and Society. All rights reserve

Fast 3D surface reconstruction by unambiguous compound phase coding

Phase shift methods have proven to be very robust and accurate for photometric 3D reconstruction. One problem of these approaches is the existence of ambiguities arising from the periodicity of the fringe patterns. While several techniques for disambiguation exist, all of them require the projection of a significant number of additional patterns. For instance, a global Gray coding sequence or several supplemental sinusoidal patterns of different periods are commonly used to complement the basic phase shift technique. In this paper we propose a new pattern strategy to reduce the total number of patterns projected by encoding multiple phases into a single sequence. This is obtained by mixing multiple equal-amplitude sinusoidal signals, which can be efficiently computed using inverse Fourier transformation. The initial phase for each fringe is then recovered independently through Fourier analysis and the unique projected coordinate is computed from the phase vectors using the disambiguation approach based on multiple periods fringes proposed by Lilienblum and Michaelis[6]. With respect to competing approaches, our method is simpler and requires fewer structured light patterns, thus reducing the measurement time, while retaining high level of accuracy. ©2009 IEEE

Class mutation operators for C++ object-oriented systems

Mutation testing is a fault injection testing technique around which a great variety of studies and tools for different programming languages have been developed. Nevertheless, the mutation testing research with respect to C++ is pending. This paper proposes a set of class mutation operators related to this language and its particular object-oriented (OO) features. In addition, an implementation technique to apply mutation testing based on the traversal of the abstract syntax tree (AST) is presented. Finally, an experiment is conducted to study the operator behaviour with different C++ programs, suggesting their usefulness in the creation of complete test suites. The analysis includes a Web service (WS) library, one of the domains where this technique can prove useful, considering its challenging testing phase and that C++ is still a reference language for critical distributed systems WS