Characteristics of contralateral carcinomas in patients with differentiated thyroid cancer larger than 1 cm

Purpose: Traditionally, total thyroidectomy has been advocated for patients with tumors larger than 1 cm. However, according to the ATA and NCCN guidelines (2015, USA), patients with tumors up to 4 cm are now eligible for lobectomy. A rationale for adhering to total thyroidectomy might be the presence of contralateral carcinomas. The purpose of this study was to describe the characteristics of contralateral carcinomas in patients with differentiated thyroid cancer (DTC) larger than 1 cm. Methods: A retrospective study was performed including patients from 17 centers in 5 countries. Adults diagnosed with DTC stage T1b-T3 N0-1a M0 who all underwent a total thyroidectomy were included. The primary endpoint was the presence of a contralateral carcinoma. Results: A total of 1

Characteristics of contralateral carcinomas in patients with differentiated thyroid cancer larger than 1 cm

textabstractPurpose: Traditionally, total thyroidectomy has been advocated for patients with tumors larger than 1 cm. However, according to the ATA and NCCN guidelines (2015, USA), patients with tumors up to 4 cm are now eligible for lobectomy. A rationale for adhering to total thyroidectomy might be the presence of contralateral carcinomas. The purpose of this study was to describe the characteristics of contralateral carcinomas in patients with differentiated thyroid cancer (DTC) larger than 1 cm. Methods: A retrospective study was performed including patients from 17 centers in 5 countries. Adults diagnosed with DTC stage T1b-T3 N0-1a M0 who all underwent a total thyroidectomy were included. The primary endpoint was the presence of a contralateral carcinoma. Results: A total of 1313 patients were included, of whom 426 (32 %) had a contralateral carcinoma. The contralateral carcinomas consisted of 288 (67 %) papillary thyroid carcinomas (PTC), 124 (30 %) follicular variant of a papillary thyroid carcinoma (FvPTC), 5 (1 %) follicular thyroid carcinomas (FTC), and 3 (1 %) Hürthle cell carcinomas (HTC). Ipsilateral multifocality was strongly associated with the presence of contralateral carcinomas (OR 2.62). Of all contralateral carcinomas, 82 % were ≤10 mm and of those 99 % were PTC or FvPTC. Even if the primary tumor was a FTC or HTC, the contralateral carcinoma was (Fv)PTC in 92 % of cases. Conclusions: This international multicenter study performed on patients with DTC larger than 1 cm shows that contralateral carcinomas occur in one third of patients and, independently of primary tumor subtype, predominantly consist of microPTC

Instagram and relationships: An analysis using focus groups

Using the focus group methodology, this thesis investigated Instagram’s impact on Knapp’s (1978) relational model, which conceptualized romantic relationships as occurring in stages. In particular, the purpose of this thesis was to gain insight on the ways that young adults (18–25) utilized Instagram’s affordances during the stages of romantic relationships. The focus groups elicited eight themes that provided insights on the motivations and behaviors of individuals who use Instagram’s affordances during romantic relationship processes. These themes included: 1) information seeking, 2) reciprocal idiosyncratic “Like,” 3) unequivocal comment, 4) significant first picture, 5) expected profile engagement, 6) reciprocal photo sharing, 7) jealousy provoking behaviors, and 8) supplemental termination behavior. The first four themes showed that Instagram’s affordances play a large role in the coming together stages of romantic relationships. The next two themes indicated that Instagram’s affordances play a large role in relationship maintenance. Finally, the last two themes indicated that Instagram’s affordances play a moderate role in the coming apart stages of relationships. The uses and gratifications theory was used to explain the findings

Interfacial instability of two inviscid fluid layers under quasi-periodic oscillations

We investigate the effect of horizontal quasi-periodic oscillations on the stability of two immiscible fluids of different densities. The two fluid layers are confined in a cavity of infinite extension in the horizontal directions. We show in the inviscid theory that the linear stability analysis leads to the quasi-periodic Mathieu equation, with damping, which describes the evolution of the interfacial amplitude. Thus, we examine the effect of horizontal quasi-periodic vibration, with two incommensurate frequencies, on the stability of the interface. The numerical study shows the existence of two types of instability: the Kelvin-Helmholtz instability and the quasi-periodic resonances. The numerical results show also that an increase of the frequency ratio has a distabilizing effect on the Kelvin-Helmholtz instability and curves converge towards those of the periodic case

Interfacial instability in a time-periodic rotating Hele-Shaw Cell

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Instability of a viscous interface under horizontal quasi-periodic oscillation

We study the linear stability of two superposed layers of viscous, immiscible fluids of different densities. The whole system is subject to horizontal quasi-periodic oscillation with two incommensurates frequencies ω1 and ω2. The spectral method and Floquet’s theory combined with Runge-Kutta method are used to solve numericelly the linear problem. We analyse the influence of the frequencies ratio$\omega = {{{\omega _1}} \over {{\omega _2}}}$, on the mariginal stability. The numerical solution shows that the quasi-periodic excitation has a stabilizing or a destabilizing effect on the Kelvin-Helmholtz instability as well as in the parametric resonances depending on the frequency ratio and the amplitudes ratio $\alpha = {{{\alpha _2}} \over {{\alpha _1}}}$