Air pollution and health indicators in a rapidly developing industrial port in the Sultanate of Oman

Background and Aims: Sohar Industrial Port (Sultanate of Oman), started to operate in 2006, containing many industries that may adversely contribute to the air quality and hence to the health status of the residents in its proximity. The study aim is to assess the health effects of air quality of the population living in the residential area around the industrial port. Methods: Health data for the area were obtained between January 1st 2006 and December 31st 2011 from the Ministry of Health, Oman. Exposure to air pollution was classified into exposure zones according to mixture methods such as, proximity, dispersion models and wind roses. Four exposure zones were developed, from High, Intermediate, Sohar city and Control zones. Age and gender standardized rates were calculated for respiratory, cardiovascular and allergic diseases in each exposure zone. Results: The crude rate ratios of respiratory diseases in the high, the intermediate and Sohar city were (1.91, 95% CI, 1.87, 1.95), (1.18, 95% CI, 1.15, 1.21) and (0.18, 95% CI, 0.18,0.19), respectively. For dermatitis, these rates were (2.16, 95% CI, 1.91,2.45) for the high exposure zone, (1.05, 95% CI, 0.91, 1.23) for the intermediate zone and (0.20, 95% CI, 0.17,0.23) for Sohar city. In addition, the high exposure zone showed an increasing yearly trend of the incidence rate from 2007 to 2009 in both respiratory diseases and dermatitis. Conclusion: Evidence of adverse health effects was found in the high and intermediate exposure zones. More rigorous modeling is underway, which will involve other diseases and confounders

The Level of Psychological Anxiety of the Coronavirus Pandemic among Omani, Bahraini and Residents Families and their Relationship to some Demographic Variables

هدفت الدراسة الحالية إلى تحديد مستوى القلق النفسي تجاه فيروس كورونا (COVID-19) لدى الأسر العُمانية والأسر البحرينية والمقيمين، وتحديد فروق مستوى القلق تجاه فيروس كورونا تعزى للجنس والمؤهل العلمي والعمر وطبيعة العمل. وتكونت عينة الدراسة من 2107 مستجيبًا تم اختيارهم بالطريقة العشوائية. وتم استخدام استبانة للقلق من إعداد الباحثات. وقد أظهرت النتائج أن مستوى القلق جاء متوسطًا، كما أظهرت النتائج عدم وجود فروق في مستوى القلق بين الأسر العمانية والبحرينية، بينما كان مستوى القلق مرتفعًا لدى المقيمين مقارنة بالمواطنين في كلا الدولتين. وأظهرت النتائج أن الإناث هن الأكثر قلقًا من الذكور. وحسب العمر فقد كان الذين أعمارهم أكثر من 40 سنة أقل قلقًا من غيرهم. وقد اتضح أن أصحاب المؤهل العلمي المتدنِ (الثانوي وأقل) أكثر قلقًا من ذوي المؤهلات التعليمية العليا. وحسب طبيعة العمل فقد اتضح أن العاطلين عن العمل أكثر قلقًا من العاملين والمتقاعدين. وقدمت الدراسة مجموعة من التوصيات.This study aimed to identify the level of psychological anxiety about the Corona Virus (COVID-19) among Omani, Bahraini and Residents families, and to identify if there are differences in the level of anxiety due to gender, qualification, age, and job title. The study sample consisted of 2107 respondents, which were selected randomly. An anxiety questionnaire that was developed by the researchers was used as the main research tool. The results showed that the level of anxiety was moderate. The study also showed no differences in the level of anxiety between Omani and Bahraini families, while the level of anxiety was high among residents compared to citizens in both countries. The results indicated that females a have higher level of anxiety than males do. In addition, respondents who were above 40 years have lower anxiety than others. As for qualification, the study showed that respondents who have a secondary level qualification (or less) are feeling anxious more than those with higher qualifications. Finally, the unemployed respondents were found to be more anxious than those who have jobs and the retirees. This study suggested a number of recommendations

Crystal structure of 2-(adamantan-1-yl)-5-(3,5-dinitrophenyl)-1,3,4-oxadiazole, C18H18N4O5

C18H18N4O5, monoclinic, P21/c (no. 14), a = 11.7553(8) Å, b = 6.4876(4) Å, c = 22.3442(15) Å, β = 91.263(7)°, V = 1703.64(19) Å3, Z = 4, Rgt (F) = 0.0531, wRref (F 2) = 0.1376, T = 160 K. CCDC no.: 2173380 The molecular structure is shown in the figure. Table 1 contains crystallographic data and Table 2 contains the list of the atoms including atomic coordinates and displacement parameters

Crystal structure of 2-({[5-(adamantan-2-yl)-2-sulfanylidene-1,3,4-oxadiazolidin-3-yl]methyl}amino)benzonitrile, C20H22N4OS

C20H22N4OS, triclinic, P (1) over bar (no. 2), a = 6.8528(3) angstrom, b = 11.3498(5) angstrom, c = 13.3896(9) angstrom, alpha = 114.083(5)degrees, beta = 104.326(4)degrees, gamma = 90.369(3)degrees, V = 914.38(9) angstrom(3), Z = 2, R-gt(F) = 0.0844, wR(ref)(F-2) = 0.2217, T = 160 K

Crystal structure of 4-ethyl-2-{[(4-nitrophenyl)methyl]sulfanyl}-6-oxo-1,6-dihydropyrimidine-5-carbonitrile, C14H12N4O3S

C14H12N4O3S, monoclinic, P21/n (no. 14), a = 12.2777(3) Å, b = 9.4312(2) Å, c = 12.9412(2) Å, β = 107.945(2)°, V = 1425.61(5) Å3, Z = 4, R gt (F) = 0.0305, wR ref (F 2) = 0.0837, T = 160 K. CCDC no.: 2059188 The molecular structure is shown in the figure. Table 1 contains crystallographic data and Table 2 contains the list of the atoms including atomic coordinates and displacement parameters

Crystal structure of 4-chloro-<i>N</i>′-[(1<i>E</i>)-pyridin-3-ylmethylidene]benzohydrazide, C₁₃H₁₀ClN₃O

C13H10ClN3O, monoclinic, P21/c (no. 14), a = 19.0933(2) Å, b = 23.0910(3) Å, c = 10.6831(2) Å, β = 90.064(1)°, V = 4710.00(12) Å3, Z = 16, R gt (F) = 0.0411, wR ref (F 2) = 0.1081, T = 160 K. CCDC no.: 223377

Crystal structure of N-ethyl-4-[3-(trifluoromethyl)-phenyl]piperazine-1-carbothioamide, C14H18F3N3S

C14H18F3N3S, monoclinic, P2(1)/c (no. 14), a = 4.61919(4) angstrom, b = 29.1507(3) angstrom, c = 11.27803(10) angstrom, beta = 94.4768(8)degrees, V = 1513.99(3) angstrom(3), Z = 4, R- gt (F) = 0.0588, wR( ref )(F-2) = 0.1579, T = 160 K

Crystal structure of 4-chloro-<i>N</i>′-[(1<i>E</i>)-(2-nitrophenyl)methylidene]benzohydrazide, C₁₄H₁₀ClN₃O₃

C14H10ClN3O3, triclinic, P1 (no. 1), alpha = 4.8813(2) angstrom, b = 6.7806(2) angstrom, c = 10.3135(2) angstrom, alpha = 98.101( 2)degrees, ss = 94.174( 2)degrees,gamma= 97.612( 3)degrees, V = 333.515(18) angstrom(3), Z = 1, R-gt(F) = 0.0270, wR(ref) (F-2 )= 0.0743, T = 160 K

Tocotrienol-Rich Fraction from Palm Oil Prevents Oxidative Damage in Diabetic Rats

Objectives: This study was carried out to determine the effects of tocotrienol-rich fraction (TRF) (200 mg/Kg) on biomarkers of oxidative stress on erythrocyte membranes and leukocyte deoxyribonucleic acid (DNA) damage in streptozotocin (STZ)-induced diabetic rats. Methods: Male rats (n = 40) were divided randomly into four groups of 10: a normal group; a normal group with TRF; a diabetic group, and a diabetic group with TRF. Following four weeks of treatment, fasting blood glucose (FBG) levels, oxidative stress markers and the antioxidant status of the erythrocytes were measured. Results: FBG levels for the STZ-induced diabetic rats were significantly increased (P &lt;0.001) when compared to the normal group and erythrocyte malondialdehyde levels were also significantly higher (P &lt;0.0001) in this group. Decreased levels of reduced glutathione and increased levels of oxidised glutathione (P &lt;0.001) were observed in STZ-induced diabetic rats when compared to the control group and diabetic group with TRF. The results of the superoxide dismutase and glutathione peroxidase activities were significantly lower in the STZ-induced diabetic rats than in the normal group (P &lt;0.001). The levels of DNA damage, measured by the tail length and tail moment of the leukocyte, were significantly higher in STZ-induced diabetic (P &lt;0.0001). TRF supplementation managed to normalise the level of DNA damage in diabetic rats treated with TRF. Conclusion: Daily supplementation with 200 mg/Kg of TRF for four weeks was found to reduce levels of oxidative stress markers by inhibiting lipid peroxidation and increasing the levels of antioxidant status in a prevention trial for STZ-induced diabetic rats

Synthesis and Biological Evaluation of Indole-2-Carboxamides with Potent Apoptotic Antiproliferative Activity as EGFR/CDK2 Dual Inhibitors

Funding Information: This work was funded by Princess Nourah bint Abdulrahman University Researchers Supporting Project Number (PNURSP2022R3), Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.Peer reviewedPublisher PD