On Critical Relative Distance of DNA Codes for Additive Stem Similarity

We consider DNA codes based on the nearest-neighbor (stem) similarity model which adequately reflects the "hybridization potential" of two DNA sequences. Our aim is to present a survey of bounds on the rate of DNA codes with respect to a thermodynamically motivated similarity measure called an additive stem similarity. These results yield a method to analyze and compare known samples of the nearest neighbor "thermodynamic weights" associated to stacked pairs that occurred in DNA secondary structures.Comment: 5 or 6 pages (compiler-dependable), 0 figures, submitted to 2010 IEEE International Symposium on Information Theory (ISIT 2010), uses IEEEtran.cl

Rx plays multiple roles in eye development

The homeobox was first identified as a common feature of Drosophila genes that control pattern formation during embryogenesis. These genes have been implicated in the regional specialization of the developing brain, spinal cord and other body structures. Homeobox gene families are highly conserved and encode DNA-binding regulatory proteins. Certain members of the homeobox gene family, including Pax6, Chx10, Lhx2, Otx2, Six3 and Six6, are crucial for development of the eye. A new family of retinal homeobox genes, Rx, is expressed early in embryogenesis in retinal stem cells. This expression pattern, along with results of overexpression and gene deletion studies, is consistent with a role for Rx in retinal stem cell specification and proliferation. In this dissertation, studies of the Rx expression in adult organisms reveal that Rx is abundantly expressed in human and mouse adult neural retina. A number of patients with anophthalmia and microphthalmia were screened and it was found that these conditions are associated with mutations in the Rx gene. The data generated in the first two projects raise a question about a role of Rx at different stages of eye development. To address this problem, a conditional allele of Rx gene was generated. This allele retains normal Rx activity but is a subject to inactivation by Cre recombinase. Using Cre recombinase under a control of forebrain-specific promoter (Foxg1 promoter), Rx conditional inactivation is achieved. Conditional animals (Rx-Foxg1-Cre) lack eyes and optic nerves but otherwise appear to be perfectly normal, making them an ideal model for anophthalmia as seen in the patient population. Analysis of Rx-Foxg1-Cre mice indicate that Rx is critical not only for the initial steps of eye development but also for axial patterning, since both, dorso-ventral and proximo-distal markers are affected

Problems of implementing e-learning in Russia

The article examines the legal grounds for using e-learning in the educational process at the university. An attempt was made to analyze readiness of universities to use elements of e-learning, as well as to identify the main problems of the implementation of e-learning in higher education in Russia.В статье рассматриваются правовые основания применения электронного обучения в образовательном процессе в вузе. Предпринята попытка дать анализ готовности вузов к применению элементов электронного обучения, а также выявить основные проблемы внедрения электронного обучения в вузах России

To the problem of the material encouragement of the labor of pedagogical workers secondary vocational education

Рассматриваются вопросы материального стимулирования труда педагогических работников организаций СПО. Дается анализ реального состояния оплаты труда с приведением результатов социологического исследования по рассматриваемой проблемеIn the article questions of the material encouragement of the labor of the pedagogical workers of organizations SPO are examined. Is carried out the analysis of the real state of the remuneration for labor with bringing of the results of a sociological study on the problem in questio

To the determination of the concept of the agreement about the formation

In the article is examined the problem of the determination of concept the agreement about the formation on the basis of the analysis of normative lawful reports and the author’s determination of the concept of the agreement about the formation is proposedРассматривается проблема определения понятия договора об образовании на основе анализа нормативных правовых актов и предлагается авторское определение понятия договора об образовани

Legal aspects of secondary vocational school teachers’ motivation to efficiency improvement

The paper discusses the methods of secondary vocational school teachers’ stimulation. We describe both monetary benefits (effective labor contract, pay increase after performance review, and bonuses) and perquisites (diplomas and honorary degrees). The topicality of this research is determined by the absence of highly-qualified teachers; this fact draws attention to the system of secondary vocational teachers’ training. The paper scrutinizes implementation of effective employment contracts in secondary vocational institutions; it also analyzes the role of such contract in pay increase. The problems of implementation of such contracts, as well as the sources of these problems, are discussed. The paper concludes that the real effect of the analyzed contract is poor. Special attention is paid to performance reviews, which are one of the ways to upgrade teacher’s qualification and consequently get higher salary. The drawbacks in the system of performance reviews of teachers are outlined, which may cause effectiveness decreaseВ статье рассматриваются методы стимулирования труда педагогических работников системы среднего профессионального образования (СПО). Рассмотрены как материальные стимулы (заключение эффективного контракта, повышение заработной платы по итогам аттестации, премирование), так и нематериальные (поощрения работников почетными грамотами, присуждение почетных званий). Актуальность исследования определена проблемой необеспеченности экономики квалифицированными рабочими кадрами, что повысило внимание к системе подготовки рабочих кадров и кадровому обеспечению организаций СПО. Проведен анализ практики внедрения эффективных контрактов с педагогами СПО, исследуется влияние данного контракта на размер заработной платы. Поднимается вопрос о существующих проблемах внедрения эффективного контракта, обозначены причины этих проблем. Обосновывается вывод о не достижении реальной эффективности рассматриваемых контракто

Legal foundation of the requirements to secondary vocational institution teachers

The need of the Russian economy for highly-qualified staff raises the question of prospective employees training at secondary vocational institutions that are respon-sible for it. The paper analyzes laws and regulations that determine qualification characteristics and requirements to secondary vocational institution teachers; it reveals the problems and offers their solution. A sociological survey was held to prove the conclusions made by the authorsПотребности российской экономики в высококвалифицированных рабочих кадрах актуализировали вопрос кадрового обеспечения образовательных организаций среднего профессионального образования, осуществляющих подготовку рабочих кадров. В статье проведен анализ действующих нормативных правовых актов в части установления квалификационных характеристик и требований к педагогическим работникам СПО, выявлены проблемы, предложены пути их решения, для аргументации использованы результаты проведенного социологического исследовани

Occupational mobility: conditions for success

The article discusses some requisites of success of occupational mobility: level of education in formal and substantive aspects, personal and business skills, self-development. Particular attention is paid to the educational component. The main reasons for the decline of its quality are identifiedРассмотрены некоторые обязательные условия успешности профессиональной мобильности: уровень образования в формальном и содержательном аспектах, личные и деловые качества, саморазвитие. Особое внимание уделено образовательной составляющей. Выделены основные причины снижения качества образовани

Lawful aspects of prekarization of the labor of the scientific-pedagogical workers

In the article the state of the working attitudes of scientific-pedagogical workers is analyzed. Are established the signs of prekarization of workers in these relations. Are examined some lawful aspects of the reasons of prekarization of the labor of the category of workers in question.В статье анализируется состояние трудовых отношений научно-педагогических работников. Установлены признаки прекаризации работников в этих отношениях. Рассмотрены некоторые правовые аспекты причин прекаризации труда рассматриваемой категории работников