Using machine learning to speed up new and upgrade detector studies: a calorimeter case

In this paper, we discuss the way advanced machine learning techniques allow physicists to perform in-depth studies of the realistic operating modes of the detectors during the stage of their design. Proposed approach can be applied to both design concept (CDR) and technical design (TDR) phases of future detectors and existing detectors if upgraded. The machine learning approaches may speed up the verification of the possible detector configurations and will automate the entire detector R\&D, which is often accompanied by a large number of scattered studies. We present the approach of using machine learning for detector R\&D and its optimisation cycle with an emphasis on the project of the electromagnetic calorimeter upgrade for the LHCb detector\cite{lhcls3}. The spatial reconstruction and time of arrival properties for the electromagnetic calorimeter were demonstrated.Comment: Talk presented on CHEP 2019 conferenc

Arrhythmic Mitral Valve Prolapse: New Menaces of the Known Disease

Mitral  valve prolapse  (MVP) has  long  been  the subject  of intense  discussions regarding the prognosis and  follow-up tactics.  In most  cases,  this condition has a benign prognosis. However, recent autopsy and follow-up studies have shown risks of developing  sudden cardiac death (SCD) in some subgroups of patients who have this clinical phenomenon. The proposed  literature review uses the population  of patients with MVP with the highest probability  of developing  life-threatening ventricular tachyarrhythmias. Patients with the presence of a complex  of changes, including  bicuspid  MVP, negative T waves in the inferior and lateral leads on a standard  12-lead electrocardiogram (ECG), and a special anatomical  phenomenon called mitral annular  disjunction  (MAD), are at high  risk of developing  ventricular  ectopias  and VSS.  A reflection  of the high  risk of SCD  in such patients  is the increase of ventricular ectopy according to Holter monitoring. The presence of a bicuspid  MVP and the MAD  phenomenon, which is a separation  of the line of attachment  of the posterior mitral leaflet from the basal inferior wall segment  towards  the atrial wall, determines the presence of a special form of MVP,  the so-called  arrhythmogenic MVP.  Hence,  in most cases MVP has a benign  prognosis. However, patients with the aforementioned ar- rhythmic  MVP  signs  must  be given  particular  attention  and  annual  follow-up including  ECG  control,  Holter  monitoring and  echocardiographic examination of the heart to reduce the risk of ventricular tachyarrhythmias and SCD development

SAFETY OF AMIODARONE USAGE IN PATIENTS WITH WOLFF-PARKINSON-WHITE SYNDROME AND ATRIAL FIBRILLATION

Amiodarone is one of the basic antiarrhytmic drugs for atrial fibrillation treatment. However application of amiodarone in patients with atrial fibrillation and Wolff-Parkinson-White syndrome can induce ventricular fibrillation. Amiodarone usage in these patients should be accompanied by readiness for performance of resuscitation. This is confirmed by clinical case presentation

PROGNOSTIC VALUE OF PATHOLOGIC Q-WAVE AND TIME OF ITS APPEARANCE IN PATIENTS WITH MYOCARDIAL INFARCTION: COMPARISON STUDY

Aim. To evaluate short- and long-term prognosis of myocardial infarction (MI) depending on occurrence of pathologic Q-wave on ECG and time of its appearance.Material and methods. 616 patients with initial ST-elevated MI were included into the study — 254 women and 362 men, aged 62.1±11.2. All patients were split up three groups depending on occurrence of pathologic Q-wave on ECG and time of its appearance. First group consisted of 311 patients with early Q-wave (during first 6 hours from onset of MI symptoms). Second group consisted of 120 patients with late Q-wave (from 6 to 24 hours from onset of MI symptoms). Third group consisted of 185 patients with non-Q-wave MI.Results. The hospital lethality in the patients with early Q-wave was significantly higher than this in patients of the second and the third groups. However, we didn’t reveal significant differences between patients with late Q-wave and patients without Q-wave on ECG. The incidences of cardiac death (sudden death and fatal MI), non-fatal MI and hospitalization because of unstable angina was assessed during next two years. During the follow-up period patients of three groups had similar incidences of the non-fatal MI and hospitalization because of unstable angina. However, incidence of cardiac death was significantly higher in early Q-wave group in comparison with non-Q-wave group.Conclusion. Occurrence of pathologic Q-wave on ECG and time of its appearance should be taken into account to assessed short- and long-term prognosis of MI

Projektowanie rozmieszczenia jednostek straży pożarnej na obszarach zamieszkanych z wykorzystaniem Systemu Informacji Geograficznej

The mathematical model to determine the required number of operational fire departments to protect settlements from fires was described. The authors of the study describe the results of automated GIS design, which is aimed at planning of activities and resource equipment for operational fire departments in settlements. The structure and functionality of the system were presentedW artykule opisano model matematyczny służący do określenia niezbędnej liczby jednostek operacyjnych służby pożarniczej potrzebnych do skutecznej ochrony przeciwpożarowej obszarów zamieszkanych. Przedstawione zostały wyniki zautomatyzowanego Systemu Informacji Geograficznej do planowania działań i określania wyposażenia jednostek operacyjnych służby pożarniczej chroniących obszary zamieszkane. W artykule autorzy prezentują strukturę systemu i jego funkcjonalne możliwości

DIAGNOSTICS AND TREATMENT OF MITRAL VALVE PROLAPSE

The mitral valve prolapse (MVP) is one of the most inconsistent diagnose. In the most cases patients with MVP have the good long-term prognosis, and therapy is aimed at reduction in psychovegetative dysfunction. Careful follow-up and timely cardiosurgical correction should be performed, if necessary, in patients with classical MPV. The choice method in these cases is the mitral valve plasty

Victory Over the Sun

general view, performance at Brooklyn Academy of Art; sets and costumes by Kazimir Malevic