Les Algues Indicatrices De L'eutrophisation Et De La Contamination De La Lagune De Korba (Cap Bon Tunisie)

The concentrations of heavy metals (Fe, Zn, Pb and Mn) were determined in two green algae (Enteromorpha intestinalis and Chaetomorpha Linium) collected from April 2012 to February 2013 in nine stations characterized by the abundance of these algae throughout the year. Determination of Pb, Mn and Zn was carried out by graphite furnace atomic absorption spectrometer while Fe by flame atomic absorption spectrometer (using the Thermo Scientific ICE 3300 AA Spectrometer). An evaluation of the degree of eutrophication is made through the physicochemical study of 31 samples in the surface water. The results underline that Korba is an eutrophic lagoon. The heavy metal concentrations in the water samples decreased in the sequence of Fe >Zn > Mn > Pb, while in Chaetomorpha Linium, Enteromorpha intestinalis and sediment exhibited the same pattern across the sites: Fe >Mn> Zn >Pb. The results show that metal accumulation capacity in both macro-algae varies according to the season and depends on the species. By comparison with other studies in the world, the levels found in the algae of Korba lagoon are relatively high except Mn. Chaetomorpha Linium could be used as an excellent indicator for heavy metals accumulation in Korba lagoon

Efficient synthesis of imino-1,3-thiazinan-4-one promoted by acetonitrile electrogenerated base and computational stadies with CB1 and 11 βHSD1 molecules

The publication was prepared with the support of the PFUR Program “5–100”

Synthesis of Two Novel Copper (II) Complexes as Potential Inhibitors of HIV-1 Protease Enzyme: Experimental and Theoretical Investigations

In this study, we report the synthesis of two new copper complexes: [Cu(C$_{11}$H$_{7}$O$_{2}$)(SCN)(C$_{10}$H$_{8}$N$_{2}$)], denoted as (C-1), and [Cu(C$_{11}$H$_{7}$O$_{2}$) (C$_{12}$H$_{8}$N$_{2}$) Cl]·H$_{2}$O, denoted as (C-2). They are based on 2,2′-bipyridine or 1,10-phenanthroline and 2-hydroxy-1-naphtaldehyde ligands. The obtained complexes were characterized by FT-IR, UV-visible spectroscopy, and single-crystal X-ray diffraction analysis. Molecular docking was employed to predict the binding mode involved in the interaction between the two synthetic copper (II) complexes and HIV-1 protease enzyme. The X-ray structural analysis revealed that the crystal structures of both complexes are mainly stabilized by several intra- and intermolecular hydrogen bonds. The fingerprint plots associated with the Hirshfeld surfaces of both complexes clearly show that H···H interactions provide the largest contributions. According to the docking results, the synthesized complexes exhibit promising features which enable them to be bound to the HIV-protease enzyme

Detection of QTLs for seedling characteristics in barley (Hordeum vulgare L.) grown under hydroponic culture condition

Abstract Background Seedling characteristics play significant roles in the growth and development of barley (Hordeum vulgare L.), including stable stand establishment, water and nutrients uptake, biotic resistance and abiotic stresses, and can influence yield and quality. However, the genetic mechanisms underlying seedling characteristics in barley are largely unknown and little research has been done. In the present work, 21 seedling-related characteristics are assessed in a barley double haploid (DH) population, grown under hydroponic conditions. Of them, leaf age (LAG), shoot height (SH), maximum root length (MRL), main root number (MRN) and seedling fresh weight (SFW) were investigated at the 13th, 20th, 27th, and 34th day after germination. The objectives were to identify quantitative trait loci (QTLs) underlying these seedling characteristics using a high-density linkage map and to reveal the QTL expression pattern by comparing the QTLs among four different seedling growth stages. Results A total of 70 QTLs were distributed over all chromosomes except 4H, and, individually, accounted for 5.01%–77.78% of phenotypic variation. Out of the 70 detected QTLs, 23 showed a major effect on 14 seedling-related characteristics. Ten co-localized chromosomal regions on 2H (five regions), 3H (two regions) and 7H (three regions) involved 39 QTLs (55.71%), each simultaneously influenced more than one trait. Meanwhile, 9 co-localized genomic regions involving 22 QTLs for five seedling characteristics (LAG, SH, MRL, MRN and SFW) at the 13th, 20th, 27th and 34th day-old seedling were common for two or more growth stages of seedling. QTL in the vicinity of Vrs1 locus on chromosome 2H with the favorable alleles from Huadamai 6 was found to have the largest main effects on multiple seedling-related traits. Conclusions Six QTL cluster regions associated with 16 seedling-related characteristics were observed on chromosome 2H, 3H and 7H. The majority of the 29 regions identified for five seedling characteristics were selectively expressed at different developmental stages. The genetic effects of 9 consecutive expression regions displayed different developmental influences at different developmental stages. These findings enhanced our understanding of a genetic basis underlying seedling characteristics in barley. Some QTLs detected here could be used for marker-assisted selection (MAS) in barley breeding