7 research outputs found
Comparative genomic hybridization detects many recurrent imbalances in central nervous system primitive neuroectodermal tumours in children
A series of 23 children with primitive neuroectodermal tumours (PNET) were analysed with comparative genomic hybridization (CGH). Multiple chromosomal imbalances have been detected in 20 patients. The most frequently involved chromosome was chromosome 17, with a gain of 17q (11 cases) and loss of 17p (eight cases). Further recurrent copy number changes were detected. Extra copies of chromosome 7 were present in nine patients and gains of 1q were detected in six patients. A moderate genomic amplification was detected in one patient, involving two sites on 3p and the whole 12p. Losses were more frequent, and especially involved the chromosomes 11 (nine cases), 10q (eight cases), 8 (six cases), X (six patients) and 3 (five cases), and part of chromosome 9 (five cases). These recurrent chromosomal changes may highlight locations of novel genes with an important role in the development and/or progression of PNET. © 1999 Cancer Research Campaig
Ultrafast spin dynamics of an individual CoPt
We have studied the ultrafast magneto-optical response of
CoPt3 ferromagnetic nanodots with diameters ranging from 0.2 to 1Â ÎĽm. Our experiments combine an accurate temporal resolution using
femtosecond laser pulses and a high spatial resolution (300Â nm)
obtained with a reflective confocal Kerr microscope. Our experimental
approach allows exploring the dynamics of the magnetization of magnetic
nanostructures over a broad temporal scale ranging from 100Â fs to 1Â ns. We
report the corresponding relaxation behavior of the electrons and the spins
initially excited with a large excess energy above the Fermi level