Characteristic of water of the Lena River and health of the population of the Republic of Sakha (Yakutia)

In the article results of sanitary epidemiological characteristics of water of the Lena River, including on indicators of parasitic safety and physiological full value are analysed. It is established that the adverse effect of water of a water source on health of the population is connected with its physiological inferiority which is caused by the low maintenance of a number of biologically active elements. The received value of factor of "utility of water» in 47 times below recommended value

PARENTERAL VIRAL HEPATITISES IN THE IRKUTSK REGION

From all group of infectious pathology viral hepatitises, from which the most priority are the parenteral hepatitises B and С, are essential for health of mankind, also the Irkutsk region isn’t an exception. The aim of the study: to assess an epidemiological situation in sharp and chronic forms of the viral hepatitises B and С in the territory of the Irkutsk region for the long-term period. Materials and methods. The retrospective analysis of an epidemiological situation on viral hepatitises B and C in Russia, Siberian Federal District and in the Irkutsk region for 2008–2016 is carried out. Results. The expressed decrease in incidence of acute viral hepatitis B is noted, at a chronic form of this disease rates of decrease had less expressed character that can be connected with carrying out by mass vaccinal prevention. The carried-out ranged distribution of territories for all forms of viral hepatitis B and viral hepatitis C in the Irkutsk region has allowed to reveal territories of risk. Conclusion. Parenteral viral hepatitises (sharp and chronic forms) are widespread in the territory of the Irkutsk region. From 43 administrative territories of the area, 24 belong to unsuccessful on incidences from which five are to territories of high epidemiological risk: cities of Irkutsk, Angarsk and Ust-Ilimsk and also Katangsky and Shelekhovsky districts

Chronic Hepatitis С in Siberian Federal District: Analysis of a Case Rate and Evolution of Genotypes of the Originator

Introduction.The chronic hepatitis C is essential for health care of the Siberian federal district in the territory of which now the incidence of the specified pathology significantly exceeds similar indicators across the Russian Federation. Materials and methods. The retrospective analysis of an epidemiological situation onе the chronic hepatitis C in the Siberian federal district for 2006–2015 included case rate assessment with use of official statistical materials. For integrated assessment of an epidemiological situation indicators of a case rate of the chronic hepatitis C and statistical criteria are used: a standard deviation and rate of a gain of a case rate and also an algorithm of calculation of an integrated indicator in the form of presentation coefficient. A genotypical variety of a virus of hepatitis C (HCV) during 2001‒2017 was studied according to the Irkutsk regional clinical consulting and diagnostic center on the basis of the analysis of 13236 PCR-positive blood samples of the sick. The chronic hepatitis C living in the territory of the Irkutsk region. Results and discussion. Assessment of the movement of a case rate of the chronic hepatitis C for the surveyed long-term period on the federal districts of Russia from the West on the East taped its body height in the designated direction. Complex assessment of indicators of a case rate in the administrative territories which are a part of the Siberian federal district in some cases significantly differs from its standard estimates and the most safe territories the Republic of Buryatia and the Omsk region. The Republic of Tyva moved from the first to the eighth rank place. Integrated approach of studying of the key epidemiological indicators allows to carry out deeper comparative assessment of the situation. In distribution of the main genotypes of HCV significant depression of the first and augmentation of the third of genotypes of the chronic hepatitis C originator is observed in recent years.Conclusions. 1 Siberian federal district is the territory of risk for chronic hepatitis C. 2 The generalized case rate indicator reflects implications of epidemic process more objectively. 3 The offered methodical approach, besides a case rate, can be used for profound assessment and other indicators. 4 Processes of globalization and social conditions promote evolution in distribution of the main genotypes of HCV