Asymptotically isometric copies of c0 in Musielak-Orlicz spaces

Criteria in order that a Musielak-Orlicz function space Lφ as well as Musielak-Orlicz sequence space lφ contains an asymptotically isometric copy of c0 are given. These results extend some results of [Y.A. Cui, H. Hudzik, G. Lewicki, Order asymptotically isometric copies of c0 in the subspaces of order continuous elements in Orlicz spaces, Journal of Convex Analysis 21 (2014)] to Musielak-Orlicz spaces

Nutraceuticals and enteric glial cells

Until recently, glia were considered to be a structural support for neurons, however further investigations showed that glial cells are equally as important as neurons. Among many different types of glia, enteric glial cells (EGCs) found in the gastrointestinal tract, have been significantly underestimated, but proved to play an essential role in neuroprotection, immune system modulation and many other functions. They are also said to be remarkably altered in different physiopathological conditions. A nutraceutical is defined as any food substance or part of a food that provides medical or health benefits, including prevention and treatment of the disease. Following the description of these interesting peripheral glial cells and highlighting their role in physiological and pathological changes, this article reviews all the studies on the effects of nutraceuticals as modulators of their functions. Currently there are only a few studies available concerning the effects of nutraceuticals on EGCs. Most of them evaluated molecules with antioxidant properties in systemic conditions, whereas only a few studies have been performed using models of gastrointestinal disorders. Despite the scarcity of studies on the topic, all agree that nutraceuticals have the potential to be an interesting alternative in the prevention and/or treatment of enteric gliopathies (of systemic or local etiology) and their associated gastrointestinal conditions.This research was funded by Ministerio de Ciencia, Innovación y Universidades, grant number PID2019-111510RB-I00 to RA and by National Science Center–SONATA 15 (number UMO- 2019/35/D/NZ7/02830 to M