Direct, high resolution, four‐dimensional measurements of the fine scale structure of Sc≫1 molecular mixing in turbulent flows

Results from highly resolved, four‐dimensional measurements of the fine structure of the fully space‐ and time‐varying Sc≫1 conserved scalar field and the associated scalar energy dissipation rate field in a turbulent flow are presented. The resolution achieved in all three spatial dimensions and in time reaches down to the local strain‐limited molecular diffusion scale in the flow, allowing all three components of the instantaneous scalar gradient vector field ∇ζ(x,t) and their time evolution at every point in the data space to be directly evaluated. Results are presented in the form of fine structure maps of the instantaneous dissipation field loge ∇ζ⋅∇ζ(x,t) in several spatially adjacent data planes within an individual three‐dimensional spatial data volume, as well as in several temporally successive data planes from a sequence of such three‐dimensional data volumes. The degree of anisotopy in the underlying scalar gradient field is characterized in terms of the joint distribution β(ϑ,φ) of spherical orientation angles. The probability density of true scalar energy dissipation rates is presented and compared with the distributions that would result from lower‐dimensional measurements of the scalar gradient vector. From this the ‘‘spottiness’’ of the scalar dissipation field is directly quantified by determining the true fraction of the total dissipation that occurs in any given volume fraction of the flow.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/70449/2/PFADEB-3-5-1115-1.pd

Four-dimensional laser induced fluorescence study of the structure of molecular mixing in turbulent flows

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/77075/1/AIAA-1994-820-515.pd

A scalar imaging velocimetry technique for fully resolved four‐dimensional vector velocity field measurements in turbulent flows

This paper presents an experimental technique for obtaining fully resolved measurements of the vector velocity field u(x,t) throughout a four‐dimensional spatiotemporal region in a turbulent flow. The method uses fully resolved four‐dimensional scalar field imaging measurements in turbulent flows [Phys. Fluids A 3, 1115 (1991)] to extract the underlying velocity field from the exact conserved scalar transport equation. A procedure for accomplishing this is described, and results from a series of test cases are presented. These involve synthetically generated scalar fields as well as actual measured turbulent flow scalar fields advected numerically by various imposed flow fields. The imposed velocity fields are exactly known, allowing a careful validation of the technique and its potential accuracy. Results obtained from a zeroth iteration of the technique are found to be very close to the exact underlying vector velocity field. Further results show that successive iterations bring the velocity field from the zeroth iteration even closer to the exact result. It is also shown that the comparatively dense velocity field information that this technique provides is well suited for accurate extraction of the more dynamically insightful strain rate and vorticity fields ϵ(x,t) and ω(x,t).Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/69930/2/PFADEB-4-10-2191-1.pd

Discipline-Specific Compared to Generic Training of Teachers in Higher Education

A recurrent theme arising in the higher education sector is the suitability and effectiveness of generic versus discipline-specific training of university teachers, who are often recruited based on their disciplinary specialties to become teachers in higher education. We compared two groups of participants who had undergone training using a generic post-graduate certificate in higher education (PGCertGeneric) versus a discipline-specific course in veterinary education (PGCertVetEd). The study was conducted using a survey that allowed comparison of participants who completed PGCertGeneric (n=21) with PGCertVetEd (n=22). Results indicated that participants from both PGCertGeneric and PGCertVetEd considered teaching to be satisfying and important to their careers, valued the teaching observation component of the course, and identified similar training needs. However, the participants of the PGCertVetEd felt that the course made them better teachers, valued the relevance of the components taught, understood course design better, were encouraged to do further courses/reading in teaching and learning, changed their teaching as a result of the course, and were less stressed about teaching as compared to the PGCertGeneric participants (p<.05). It is likely that the PGCertVetEd, which was designed and developed by veterinarians with a wider understanding of the veterinary sector, helped the participants perceive the training course as suited to their needs

Statin use is associated with fewer periodontal lesions: A retrospective study

<p>Abstract</p> <p>Background</p> <p>Inflammatory processes are considered to participate in the development of cardiovascular disease (CVD). Statins have been used successfully in the prevention and treatment of coronary heart disease. Chronic periodontitis has been suggested to contribute to CVD. The aim of this study was to examine the association of statin use and clinical markers of chronic periodontitis.</p> <p>Methods</p> <p>Periodontal probing pocket depth (PPD) values were collected from dental records of 100 consecutive adult patients referred to a university dental clinic for treatment of advanced chronic periodontitis. A novel index, Periodontal Inflammatory Burden Index (PIBI), was derived from the PPD values to estimate systemic effects of periodontitis.</p> <p>Results</p> <p>Periodontitis patients taking statins had a 37% lower number of pathological periodontal pockets than those without statin medication (P = 0.00043). PIBI, which combines and unifies the data on PPD, was 40% smaller in statin using patients than in patients without statin (P = 0.00069). PIBI of subjects on simvastatin and atorvastatin both differed significantly from patients without statin and were on the same level. The subjects' number of teeth had no effect on the results</p> <p>Conclusion</p> <p>Patients on statin medication exhibit fewer signs of periodontal inflammatory injury than subjects without the statin regimen. PIBI provides a tool for monitoring inflammatory load of chronic periodontitis. The apparent beneficial effects of statins may in part be mediated by their pleiotropic anti-inflammatory effect on periodontal tissue.</p

Ancestry reported by white adults with cutaneous melanoma and control subjects in central Alabama

BACKGROUND: We sought to evaluate the hypothesis that the high incidence of cutaneous melanoma in white persons in central Alabama is associated with a predominance of Irish and Scots descent. METHODS: Frequencies of country of ancestry reports were tabulated. The reports were also converted to scores that reflect proportional countries of ancestry in individuals. Using the scores, we computed aggregate country of ancestry indices as estimates of group ancestry composition. HLA-DRB1*04 allele frequencies and relationships to countries of ancestry were compared in probands and controls. Results were compared to those of European populations with HLA-DRB1*04 frequencies. RESULTS: Ninety evaluable adult white cutaneous melanoma probands and 324 adult white controls reported countries of ancestry of their grandparents. The respective frequencies of Ireland, and Scotland and "British Isles" reported countries of ancestry were significantly greater in probands than in controls. The respective frequencies of Wales, France, Italy and Poland were significantly greater in controls. 16.7% of melanoma probands and 23.8% of controls reported "Native American" ancestry; the corresponding "Native American" country of ancestry index was not significantly different in probands and controls. The frequency of HLA-DRB1*04 was significantly greater in probands, but was not significantly associated with individual or aggregate countries of ancestry. The frequency of DRB1*04 observed in Alabama was compared to DRB1*04 frequencies reported from England, Wales, Ireland, Orkney Island, France, Germany, and Australia. CONCLUSION: White adults with cutaneous melanoma in central Alabama have a predominance of Irish, Scots, and "British Isles" ancestry and HLA-DRB1*04 that likely contributes to their high incidence of cutaneous melanoma