59 research outputs found
Analytical solutions for the electric field and dielectrophoretic force in a dielectrophoretic focusing electrode structure
The analysis of the movement of particles in a nonuniform field requires accurate knowledge of theelectric field distribution. In this letter, the Schwarz–Christoffel mapping method is used to analytically solve the electric field distribution in a dielectrophoretic focusing electrode structure.The analytical result for the electric field distribution is validated by comparison with numericalsimulations using the finite element method. The electric field solution is used to calculate the dielectrophoretic force on a particle in the syste
DNA deaminases: AIDing hormones in immunity and cancer
It is well established that hormones can cause cancer, much less known is how they induce this change in our somatic cells. This review highlights the recent finding that estrogen can exert its DNA-damaging potential by directly activating DNA deaminases. This recently discovered class of proteins deaminate cytosine to uracil in DNA, and are essential enzymes in the immune system. The enhanced production of a given DNA deaminase, induced by estrogen, can lead not only to a more active immune response, but also to an increase in mutations and oncogenic translocations. Identifying the direct molecular link between estrogen and a mutation event provides us with new targets for studying and possibly inhibiting the pathological side-effects of estrogen
Analytical solutions of ac electrokinetics in interdigitated electrode arrays: Electric field, dielectrophoretic and traveling-wave dielectrophoretic forces
Analysis of the movement of particles in a nonuniform field requires accurate knowledge of the electric field distribution in the system. This paper describes a method for analytically solving the electric field distribution above interdigitated electrode arrays used for dielectrophoresis (DEP) and traveling wave dielectrophoresis (twDEP), using the Schwarz-Christoffel mapping method. The electric field solutions are used to calculate the dielectrophoretic force in both cases, and the traveling wave dielectrophoretic force and the electrorotational torque for the twDEP case. This method requires no approximations and can take into account the Neumann boundary condition used to represent an insulating lid and lower substrate. The analytical results of the electric field distributions are validated for different geometries by comparison with numerical simulations using the finite element method
Conformal mapping: methods and applications
Beginning with a brief survey of some basic mathematical concepts, this graduate-level text proceeds to discussions of a selection of mapping functions, numerical methods and mathematical models, nonplanar fields and nonuniform media, static fields in electricity and magnetism, and transmission lines and waveguides. Other topics include vibrating membranes and acoustics, transverse vibrations and buckling of plates, stresses and strains in an elastic medium, steady state heat conduction in doubly connected regions, transient heat transfer in isotropic and anisotropic media, and fluid flow. Revision of 1991 ed. 247 figures. 38 tables. Appendices
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