467 research outputs found
Investigating Advances in the Acquisition of Secure Systems Based on Open Architecture, Open Source Software, and Software Product Lines
Naval Postgraduate School Acquisition Research Progra
Parallel block preconditioners for virtual element discretizations of the time-dependent Maxwell equations
The focus of this study is the construction and numerical validation of
parallel block preconditioners for low order virtual element discretizations of
the three-dimensional Maxwell equations. The virtual element method (VEM) is a
recent technology for the numerical approximation of partial differential
equations (PDEs), that generalizes finite elements to polytopal computational
grids. So far, VEM has been extended to several problems described by PDEs, and
recently also to the time-dependent Maxwell equations. When the time
discretization of PDEs is performed implicitly, at each time-step a large-scale
and ill-conditioned linear system must be solved, that, in case of Maxwell
equations, is particularly challenging, because of the presence of both H(div)
and H(curl) discretization spaces. We propose here a parallel preconditioner,
that exploits the Schur complement block factorization of the linear system
matrix and consists of a Jacobi preconditioner for the H(div) block and an
auxiliary space preconditioner for the H(curl) block. Several parallel
numerical tests have been perfomed to study the robustness of the solver with
respect to mesh refinement, shape of polyhedral elements, time step size and
the VEM stabilization parameter.Comment: 21 pages, 10 tables, 4 figure
Dynamical density functional theory analysis of the laning instability in sheared soft matter
Using dynamical density functional theory (DDFT) methods we investigate the laning instability of a sheared colloidal suspension. The nonequilibrium ordering at the laning transition is driven by nonaffine particle motion arising from interparticle interactions. Starting from a DDFT which incorporates the nonaffine motion, we perform a linear stability analysis that enables identification of the regions of parameter space where lanes form. We illustrate our general approach by applying it to a simple one- component fluid of soft penetrable particles
Software Licenses in Context: The Challenge of Heterogeneously-Licensed Systems
The prevailing approach to free/open source software and licenses has been that each system is developed, distributed, and used under the terms of a single license. But it is increasingly common for information systems and other software to be composed with components from a variety of sources, and with a diversity of licenses. This may result in possible license conflicts and organizational liability for failure to fulfill license obligations. Research and practice to date have not kept up with this sea-change in software licensing arising from free/open source software development. System consumers and users consequently rely on ad hoc heuristics (or costly legal advice) to determine which license rights and obligations are in effect, often with less than optimal results; consulting services are offered to identify unknowing unauthorized use of licensed software in information systems; and researchers have shown how the choice of a (single) specific license for a product affects project success and system adoption. Legal scholars have examined how pairs of software licenses conflict but only in simple contexts. We present an approach for understanding and modeling software licenses, as well as for analyzing conflicts among groups of licenses in realistic system contexts, and for guiding the acquisition, integration, or development of systems with free/open source components in such an environment. This work is based on an empirical analysis of representative software licenses and of heterogeneously-licensed systems. Our approach provides guidance for achieving a “best-of-breed” component strategy while obtaining desired license rights in exchange for acceptable obligations
Parallel inexact Newton-Krylov and quasi-Newton solvers for nonlinear elasticity
In this work, we address the implementation and performance of inexact
Newton-Krylov and quasi-Newton algorithms, more specifically the BFGS method,
for the solution of the nonlinear elasticity equations, and compare them to a
standard Newton-Krylov method. This is done through a systematic analysis of
the performance of the solvers with respect to the problem size, the magnitude
of the data and the number of processors in both almost incompressible and
incompressible mechanics. We consider three test cases: Cook's membrane
(static, almost incompressible), a twist test (static, incompressible) and a
cardiac model (complex material, time dependent, almost incompressible). Our
results suggest that quasi-Newton methods should be preferred for compressible
mechanics, whereas inexact Newton-Krylov methods should be preferred for
incompressible problems. We show that these claims are also backed up by the
convergence analysis of the methods. In any case, all methods present adequate
performance, and provide a significant speed-up over the standard Newton-Krylov
method, with a CPU time reduction exceeding 50% in the best cases
Cadmium-Induced Disruption in 24-h Expression of Clock and Redox Enzyme Genes in Rat Medial Basal Hypothalamus: Prevention by Melatonin
In a previous study we reported that a low daily p.o. dose of cadmium (Cd) disrupted the circadian expression of clock and redox enzyme genes in rat medial basal hypothalamus (MBH). To assess whether melatonin could counteract Cd activity, male Wistar rats (45 days of age) received CdCl2 (5 ppm) and melatonin (3 μg/mL) or vehicle (0.015% ethanol) in drinking water. Groups of animals receiving melatonin or vehicle alone were also included. After 1 month, MBH mRNA levels were measured by real-time PCR analysis at six time intervals in a 24-h cycle. In control MBH Bmal1 expression peaked at early scotophase, Per1 expression at late afternoon, and Per2 and Cry2 expression at mid-scotophase, whereas neither Clock nor Cry1 expression showed significant 24-h variations. This pattern was significantly disrupted (Clock, Bmal1) or changed in phase (Per1, Per2, Cry2) by CdCl2 while melatonin counteracted the changes brought about by Cd on Per1 expression only. In animals receiving melatonin alone the 24-h pattern of MBH Per2 and Cry2 expression was disrupted. CdCl2 disrupted the 24-h rhythmicity of Cu/Zn- and Mn-superoxide dismutase (SOD), nitric oxide synthase (NOS)-1, NOS-2, heme oxygenase (HO)-1, and HO-2 gene expression, most of the effects being counteracted by melatonin. In particular, the co-administration of melatonin and CdCl2 increased Cu/Zn-SOD gene expression and decreased that of glutathione peroxidase (GPx), glutathione reductase (GSR), and HO-2. In animals receiving melatonin alone, significant increases in mean Cu/Zn and Mn-SOD gene expression, and decreases in that of GPx, GSR, NOS-1, NOS-2, HO-1, and HO-2, were found. The results indicate that the interfering effect of melatonin on the activity of a low dose of CdCl2 on MBH clock and redox enzyme genes is mainly exerted at the level of redox enzyme gene expression
Quasicrystal formation in binary soft matter mixtures
Using a strategy that may be applied in theory or in experiments, we identify the regime in which a model binary soft matter mixture forms quasicrystals. The system is described using classical density functional theory combined with integral equation theory. Quasicrystal formation requires particle ordering with two characteristic length scales in certain particular ratios. How the length scales are related to the form of the pair interactions is reasonably well understood for one-component systems, but less is known for mixtures. In our model mixture of big and small colloids confined to an interface, the two length scales stem from the range of the interactions between pairs of big particles and from the cross big-small interactions, respectively. The small-small length scale is not significant. Our strategy for finding quasicrystals involves tuning locations of maxima in the dispersion relation, or equivalently in the liquid state partial static structure factors
COVID-19 lockdown and self-perceived changes of food choice, waste, impulse buying and their determinants in italy: Quaranteat, a cross-sectional study
Data about self-perceived food choice (FC) changes and their determinants during COVID-19 lockdowns are limited. This study investigated how the Italian lockdown affected self-perceived food purchases (FP), occurrence of impulse buying (IB), household food waste production (HFWP) and their determinants. A web-based cross-sectional survey was distributed in May 2020, collecting an opportunistic sample of the Italian population. A total of 1865 (70% females) people were enrolled, the median age was 29 (IQR 16.0). Most of the sample increased overall FP (53.4%), food consumption (43.4%), reduced HFWP (53.7%) and halved the prevalence of IB (20.9%) compared to the period before the lockdown (42.5%). Baking ingredients, fresh vegetables, fresh fruit and chocolate had the largest sales increase by individuals, while bakery products, fresh fish and salted snacks purchases highly decreased. Increased FP was associated with the occurrence of IB (adjOR 2.48, p p = 0.003). Multivariable logistic regressions revealed occurrence of IB was associated with low perceived dietary quality (adjOR 2.22, p p p p p = 0.002). The Italian lockdown highly affected FC behaviours, leading to positive and sustainable habits towards food purchase and consumption. Public health interventions are needed to keep these new positive effects and avoid negative consequences in case of future lockdowns
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